Search Results - "Hurwitz, C A"

Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995) by SILVERMAN, L. B, DECLERCK, L, SCHORIN, M. A, LIPTON, J. M, COHEN, H. J, SALLAN, S. E, GELBER, R. D, DALTON, V. Kimball, ASSELIN, B. L, BARR, R. D, CLAVELL, L. A, HURWITZ, C. A, MOGHRABI, A, SAMSON, Y

“…The Dana-Farber Cancer Institute (DFCI) ALL consortium has been conducting clinical trials in childhood acute lymphoblastic leukemia (ALL) since 1981. The…”
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Experience With 2-Chlorodeoxyadenosine in Previously Untreated Children With Newly Diagnosed Acute Myeloid Leukemia and Myelodysplastic Diseases by KRANCE, R. A, HURWITZ, C. A, BLAKLEY, R. L, RIBEIRO, R. C, HEAD, D. R, RAIMONDI, S. C, BEHM, F. G, CREWS, K. R, SRIVASTAVA, D. K, MAHMOUD, H, ROBERTS, W. M, TONG, X

“…To develop more effective chemotherapy regimens for childhood acute myelogenous leukemia (AML). Between June 1991 and December 1996, we administered the…”
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Substituting dexamethasone for prednisone complicates remission induction in children with acute lymphoblastic leukemia by Hurwitz, Craig A., Silverman, Lewis B., Schorin, Marshall A., Clavell, Luis A., Dalton, Virginia K., Glick, Kathleen M., Gelber, Richard D., Sallan, Stephen E.

“…BACKGROUND The authors report the occurrence of fatal or near‐fatal sepsis in 16 of 38 children with newly diagnosed acute lymphoblastic leukemia (ALL) treated…”
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Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation by Sandoval, C, Pui, C H, Bowman, L C, Heaton, D, Hurwitz, C A, Raimondi, S C, Behm, F G, Head, D R

“…Patient records were reviewed to identify cases of secondary acute myeloid leukemia (AML) with clinical and cytogenetic features characteristic of classic…”
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Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumors by Sonnichsen, D S, Hurwitz, C A, Pratt, C B, Shuster, J J, Relling, M V

“…Our aim was to evaluate the pharmacokinetics and pharmacodynamics of paclitaxel (Taxol; Bristol-Myers Squibb Co, Princeton, NJ) in children, and to determine…”
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Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone by WABER, D. P, CARPENTIERI, S. C, KLAR, N, SILVERMAN, L. B, SCHWENN, M, HURWITZ, C. A, MULLENIX, P. J, TARBELL, N. J, SALLAN, S. E

“…The cognitive sequelae of treatment for childhood acute lymphoblastic leukemia (ALL) were compared in a group of patients who received dexamethasone during the…”
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A Phase I Trial of Bryostatin-1 in Children with Refractory Solid Tumors: A Pediatric Oncology Group Study by WEITMAN, S, LANGEVIN, A.-M, BERKOW, R. L, THOMAS, P. J, HURWITZ, C. A, KRAFT, A. S, DUBOWY, R. L, SMITH, D. L, BERNSTEIN, M

“…Bryostatin-1, a macrocyclic lactone, appears to elicit a wide range of biological responses including modulation of protein kinase C (PKC). PKC, one of the…”
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Tretinoin toxicity in children with acute promyelocytic leukaemia by Mahmoud, H H, Hurwitz, C A, Roberts, W M, Santana, V M, Ribeiro, R C, Krance, R A

“…Tretinoin is effective in acute promyelocytic leukaemia in adults. Data about its efficacy and safety in children are limited. We have treated 9 children with…”
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Phase I trial of paclitaxel in children with refractory solid tumors: a Pediatric Oncology Group Study by Hurwitz, C A, Relling, M V, Weitman, S D, Ravindranath, Y, Vietti, T J, Strother, D R, Ragab, A H, Pratt, C B

“…A phase I study was performed to describe the principal toxicities and identify the maximum-tolerated dose (MTD) of Taxol (paclitaxel; Bristol-Myers Squibb Co,…”
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Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01 by Silverman, Lewis B., Gelber, Richard D., Dalton, Virginia Kimball, Asselin, Barbara L., Barr, Ronald D., Clavell, Luis A., Hurwitz, Craig A., Moghrabi, Albert, Samson, Yvan, Schorin, Marshall A., Arkin, Steven, Declerck, Lieven, Cohen, Harvey J., Sallan, Stephen E.

“…The Dana-Farber Cancer Institute (DFCI) acute lymphoblastic leukemia (ALL) Consortium Protocol 91-01 was designed to improve the outcome of children with newly…”
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Asynchronous Antigen Expression in B Lineage Acute Lymphoblastic Leukemia by Hurwitz, Craig A., Loken, Michael R., Graham, Michael L., Karp, Judith E., Borowitz, Michael J., Pullen, D. Jeanette, Civin, Curt I.

“…Cell surface phenotypes of 113 B lineage acute lymphocytic leukemia (ALL) cases, defined by the presence of HLA-DR and at least one B-cell-specific antigen…”
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Parenteral nutrition associated with increased infection rate in children with cancer by Christensen, M L, Hancock, M L, Gattuso, J, Hurwitz, C A, Smith, C, McCormick, J, Mirro, Jr, J

“…Recent meta-analyses of published controlled studies concluded that adult patients with cancer randomly assigned to receive parenteral nutrition had higher…”
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Diffuse alveolar hemorrhage associated with Mycoplasma hominis respiratory tract infection in a bone marrow transplant recipient by Kane, J R, Shenep, J L, Krance, R A, Hurwitz, C A

“…An 18-year-old woman developed respiratory distress and diffuse pulmonary infiltrates after allogeneic bone marrow transplantation. Bronchoalveolar lavage…”
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Complete hematologic remissions induced by 2-chlorodeoxyadenosine in children with newly diagnosed acute myeloid leukemia by SANTANA, V. M, HURWITZ, C. A, BLAKLEY, R. L, CROM, W. R, XIAOLONG LUO, ROBERTS, W. M, RIBEIRO, R, HAZEM MAHMOUD, KRANCE, R. A

“…The majority of children with acute myeloid leukemia (AML) who are treated exclusively with chemotherapy die of progressive disease. Improvement in outcome…”
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N-CAM (CD56) expression by CD34+ malignant myeloblasts has implications for minimal residual disease detection in acute myeloid leukemia by Coustan-Smith, E, Behm, F G, Hurwitz, C A, Rivera, G K, Campana, D

“…The molecules detected by CD34 and CD56 monoclonal antibodies are simultaneously expressed in approximately 20% of childhood acute myeloid leukemia (AML)…”
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Clinical significance of CD10 expression in childhood acute lymphoblastic leukemia by Pui, C H, Rivera, G K, Hancock, M L, Raimondi, S C, Sandlund, J T, Mahmoud, H H, Ribeiro, R C, Furman, W L, Hurwitz, C A, Crist, W M

“…The independent significance of CD10 expression in childhood acute lymphoblastic leukemia (ALL) is uncertain because most studies have not adjusted for other…”
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Invasive fungal disease in pediatric acute leukemia patients with fever and neutropenia during induction chemotherapy: a multivariate analysis of risk factors by Wiley, J M, Smith, N, Leventhal, B G, Graham, M L, Strauss, L C, Hurwitz, C A, Modlin, J, Mellits, D, Baumgardner, R, Corden, B J

“…We evaluated the courses of 115 consecutive cases of pediatric acute leukemia treated with induction chemotherapy. Seventy-two patients developed fever…”
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Treatment of patients with acute myelogenous leukemia: review of clinical trials of the past decade by Hurwitz, C A, Mounce, K G, Grier, H E

“…We discuss the history and progress of treatment for acute myelogenous leukemia (AML) in children as it has evolved over the past decade. We review the results…”
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XomaZyme-CD5 immunotoxin in conjunction with partial T cell depletion for prevention of graft rejection and graft-versus-host disease after bone marrow transplantation from matched unrelated donors by Koehler, M, Hurwitz, C A, Krance, R A, Coustan-Smith, E, Williams, L L, Santana, V, Ribeiro, R C, Brenner, M K, Heslop, H E

“…Patients who receive bone marrow transplants from unrelated donors have a high incidence of graft-versus-host disease (GVHD). If the donor marrow is first T…”
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Flow cytometric detection of rare normal human marrow cells with immunophenotypes characteristic of acute lymphoblastic leukemia cells by Hurwitz, C A, Gore, S D, Stone, K D, Civin, C I

“…Rare subpopulations of normal marrow B lymphoid cells expressing immunophenotypes typically found in B-lineage acute lymphoblastic leukaemias (ALL) were sought…”
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