Search Results - "Hurtig, Mark B"
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Rotator cuff repair: a review of surgical techniques, animal models, and new technologies under development
Published in Journal of shoulder and elbow surgery (01-12-2016)“…Rotator cuff tears are the most common musculoskeletal injury occurring in the shoulder. Current surgical repair fails to heal in 20% to 95% of patients,…”
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2
Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair
Published in Journal of orthopaedic research (01-09-2009)“…Meniscus injury is a frequently encountered clinical orthopedic issue and is epidemiologically correlated to osteoarthritis. The development of new treatments…”
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3
Chitosan–Platelet-Rich Plasma Implants Improve Rotator Cuff Repair in a Large Animal Model: Pivotal Study
Published in Pharmaceutics (18-11-2021)“…The purpose of this study was to assess the safety and efficacy of chitosan–platelet-rich plasma (PRP) hybrid implants used as an adjunct to surgical rotator…”
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4
Culturing Articular Cartilage Explants in the Presence of Autologous Adipose Tissue Modifies Their Inflammatory Response to Lipopolysaccharide
Published in Mediators of inflammation (12-11-2020)“…The purpose of the current study was to explore the effect of autologous adipose tissue on cartilage responses to lipopolysaccharide (LPS). We hypothesized…”
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5
Determination of the prevalence and severity of metacarpophalangeal joint osteoarthritis in Thoroughbred racehorses via quantitative macroscopic evaluation
Published in American journal of veterinary research (01-11-2010)“…To determine the prevalence and severity of osteoarthritis in the metacarpophalangeal joints of Thoroughbred racehorses via development and validation of a…”
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6
Non-invasive electroarthrography measures cartilage in live horses and correlates to direct measurements of cartilage streaming potentials in weight bearing regions of equine metacarpophalangeal joints
Published in Osteoarthritis and cartilage (01-10-2024)“…To perform non-invasive Electroarthrography (EAG) on live horses and establish relationships between EAG and direct measurements of cartilage streaming…”
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7
Chitosan-platelet-rich plasma implants improve rotator cuff repair in a large animal model: Pilot study
Published in Journal of biomaterials applications (01-08-2022)“…Freeze-dried formulations of chitosan can be solubilized in platelet-rich plasma (PRP) to form injectable implants that are used as an adjunct treatment during…”
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An investigation of 2 techniques for optimizing joint surface congruency using multiple cylindrical osteochondral autografts
Published in Arthroscopy (01-01-2001)“…Purpose: To compare 2 techniques for optimizing joint congruency for miniature osteochondral autografting in the knee: intrinsic postoperative forces acting on…”
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9
Poly(ester amide) particles for controlled delivery of celecoxib
Published in Journal of biomedical materials research. Part A (01-06-2019)“…Many potential pharmacological treatments for osteoarthritis can result in undesirable side effects due to the systemic administration of drugs, making the…”
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10
Interspecies comparison of subchondral bone properties important for cartilage repair
Published in Journal of orthopaedic research (01-01-2015)“…ABSTRACT Microfracture repair tissue in young adult humans and in rabbit trochlea is frequently of higher quality than in corresponding ovine or horse models…”
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11
Analysis of the subchondral microarchitecture of the distopalmar aspect of the third metacarpal bone in racing Thoroughbreds
Published in American journal of veterinary research (01-10-2010)“…To determine the anisotropic characteristics of the microarchitecture of the subchondral bone (SCB) plate and trabecular bone (TBB) of the distopalmar aspect…”
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12
In Vitro Generated Intervertebral Discs: Toward Engineering Tissue Integration
Published in Tissue engineering. Part A (01-09-2017)“…The intervertebral disc (IVD) is composed of nucleus pulposus (NP) surrounded by multilamellated annulus fibrosus (AF), and is located between the vertebral…”
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13
Investigation of the passive mechanical properties of spine muscles following disruption of the thoracolumbar fascia and erector spinae aponeurosis, as well as facet injury in a rat
Published in The spine journal (01-04-2018)“…Muscle tissue is known to remodel in response to changes to its mechanical environment. Alterations in passive mechanical properties of muscles can influence…”
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14
Non-invasive Electroarthrography Measures Load-Induced Cartilage Streaming Potentials via Electrodes Placed on Skin Surrounding an Articular Joint
Published in Cartilage (01-12-2021)“…Objective We aimed to demonstrate that electroarthrography (EAG) measures streaming potentials originating in the cartilage extracellular matrix during load…”
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15
Influence of species and anatomical location on chondrocyte expansion
Published in BMC musculoskeletal disorders (17-05-2005)“…Bovine articular cartilage is often used to study chondrocytes in vitro. It is difficult to correlate in vitro studies using bovine chondrocytes with in vivo…”
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Freeze-Dried Chitosan-Platelet-Rich Plasma Implants for Rotator Cuff Tear Repair: Pilot Ovine Studies
Published in ACS biomaterials science & engineering (12-11-2018)“…Rotator cuff tears are a very common shoulder pathology. Different suturing techniques have been used for surgical cuff repair, but failure of healing remains…”
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Preclinical Studies for Cartilage Repair: Recommendations from the International Cartilage Repair Society
Published in Cartilage (01-04-2011)“…Investigational devices for articular cartilage repair or replacement are considered to be significant risk devices by regulatory bodies. Therefore animal…”
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Effect of a Rapidly Degrading Presolidified 10 kDa Chitosan/Blood Implant and Subchondral Marrow Stimulation Surgical Approach on Cartilage Resurfacing in a Sheep Model
Published in Cartilage (01-10-2017)“…Objective This study tested the hypothesis that presolidified chitosan-blood implants are retained in subchondral bone channels perforated in critical-size…”
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19
Implantation of Scaffold-Free Engineered Cartilage Constructs in a Rabbit Model for Chondral Resurfacing
Published in Artificial organs (01-02-2014)“…Joint resurfacing techniques offer an attractive treatment for damaged or diseased cartilage, as this tissue characteristically displays a limited capacity for…”
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Characterization of initial microfracture defects in human condyles
Published in The Journal of knee surgery (01-10-2013)“…Microfracture (MFX) is a cartilage repair technique that depends on cell migration from marrow-rich trabecular bone cavities into the cartilage lesion. This…”
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