Search Results - "Hurst, C."

Commissioning of the Varian TrueBeam linear accelerator: A multi-institutional study by Glide-Hurst, C., Bellon, M., Foster, R., Altunbas, C., Speiser, M., Altman, M., Westerly, D., Wen, N., Zhao, B., Miften, M., Chetty, I. J., Solberg, T.

“…Purpose: Latest generation linear accelerators (linacs), i.e., TrueBeam (Varian Medical Systems, Palo Alto, CA) and its stereotactic counterpart, TrueBeam STx,…”
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Changes realized from extended bit-depth and metal artifact reduction in CT by Glide-Hurst, C., Chen, D., Zhong, H., Chetty, I. J.

“…Purpose: High-Z material in computed tomography (CT) yields metal artifacts that degrade image quality and may cause substantial errors in dose calculation…”
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Efficacy and Safety of Collagenase Clostridium Histolyticum in the Treatment of Proximal Interphalangeal Joints in Dupuytren Contracture: Combined Analysis of 4 Phase 3 Clinical Trials by Badalamente, Marie A., PhD, Hurst, Lawrence C., MD, Benhaim, Prosper, MD, Cohen, Brian M., PhD

“…Purpose To examine the results of proximal interphalangeal (PIP) joint contractures from 4 phase 3 clinical trials of collagenase clostridium histolyticum…”
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Definitions matter: detection rates and perinatal outcome for infants classified prenatally as having late fetal growth restriction using SMFM biometric vs ISUOG/Delphi consensus criteria by Schreiber, V., Hurst, C., Silva Costa, F., Stoke, R., Turner, J., Kumar, S.

“…Objectives Fetal growth restriction (FGR) is often secondary to placental dysfunction and is suspected prenatally based on biometric or circulatory…”
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RGS14 limits seizure-induced mitochondrial oxidative stress and pathology in hippocampus by Harbin, N.H., Lustberg, D.J., Hurst, C., Pare, J., Crotty, K.M., Waters, A.L., Yeligar, S.M., Smith, Y., Seyfried, N.T., Weinshenker, D., Hepler, J.R.

“…RGS14 is a complex multifunctional scaffolding protein that is highly enriched within pyramidal cells (PCs) of hippocampal area CA2. In these neurons, RGS14…”
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TU‐F‐BRB‐03: Clinical Implementation of MR‐Based Motion Management by Glide‐Hurst, C.

“…The current clinical standard of organ respiratory imaging, 4D‐CT, is fundamentally limited by poor soft‐tissue contrast and imaging dose. These limitations…”
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MO-DE-207A-03: Characterization of Potential Gains in a Novel Exponential 4DCT Reconstruction Algorithm by Morris, E.D., Klahr, P., Glide-Hurst, C.

“…Purpose: To sample the breathing cycle and obtain accurate target volumes, 4DCT requires the entire field of view (FOV) to be illuminated during one breathing…”
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Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer by TOMLINSON, D. C, HURST, C. D, KNOWLES, M. A

“…More than 60% of low-grade non-invasive papillary urothelial cell carcinomas contain activating point mutations of fibroblast growth factor receptor 3 (FGFR3)…”
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Applying the Clinician-reported Genetic testing Utility InDEx (C-GUIDE) to genome sequencing: further evidence of validity by Hayeems, Robin Z, Luca, Stephanie, Hurst, Anna C E, Cochran, Meagan, Owens, Chelsea, Hossain, Alomgir, Chad, Lauren, Meyn, M Stephen, Pullenayegum, Eleanor, Ungar, Wendy J, Bick, David

“…Genome sequencing (GS) outperforms other rare disease diagnostics, but standardized approaches to assessing its clinical utility are limited. This study…”
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Do improvements in clinical practice guidelines alter pregnancy outcomes in asthmatic women? A single-center retrospective cohort study by Robinson, J. L., Gatford, K. L., Hurst, C. P., Clifton, V. L., Morrison, J. L., Stark, M. J.

“…Asthma occurs in ∼17% of Australian pregnancies and is associated with adverse perinatal outcomes, which worsen with poor asthma control. Consequently, the…”
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CD4 count and risk of anti-tuberculosis drug-associated cutaneous reactions in HIV-infected Thai patients by Boonyagars, L., Hirunwiwatkul, P., Hurst, C. P.

“…OBJECTIVES: Tuberculosis (TB) is a major cause of morbidity and mortality in human immunodeficiency virus (HIV) infected patients. However, anti-tuberculosis…”
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De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay by Hiatt, Susan M, Neu, Matthew B, Ramaker, Ryne C, Hardigan, Andrew A, Prokop, Jeremy W, Hancarova, Miroslava, Prchalova, Darina, Havlovicova, Marketa, Prchal, Jan, Stranecky, Viktor, Yim, Dwight K C, Powis, Zöe, Keren, Boris, Nava, Caroline, Mignot, Cyril, Rio, Marlene, Revah-Politi, Anya, Hemati, Parisa, Stong, Nicholas, Iglesias, Alejandro D, Suchy, Sharon F, Willaert, Rebecca, Wentzensen, Ingrid M, Wheeler, Patricia G, Brick, Lauren, Kozenko, Mariya, Hurst, Anna C E, Wheless, James W, Lacassie, Yves, Myers, Richard M, Barsh, Gregory S, Sedlacek, Zdenek, Cooper, Gregory M

“…Mutations that alter signaling of RAS/MAPK-family proteins give rise to a group of Mendelian diseases known as RASopathies. However, among RASopathies, the…”
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The Efficacy and Safety of Concurrent Collagenase Clostridium Histolyticum Injections for 2 Dupuytren Contractures in the Same Hand: A Prospective, Multicenter Study by Gaston, R. Glenn, MD, Larsen, Søren Erik, MD, Pess, Gary M., MD, Coleman, Stephen, MBBS, Dean, Brian, MS, Cohen, Brian M., PhD, Kaufman, Gregory J., MD, Tursi, James P., MD, Hurst, Lawrence C., MD

“…Purpose To evaluate efficacy and safety of concurrent administration of 2 collagenase clostridium histolyticum (CCH) injections to treat 2 joints in the same…”
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PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma by Ross, R L, McPherson, H R, Kettlewell, L, Shnyder, S D, Hurst, C D, Alder, O, Knowles, M A

“…Many urothelial carcinomas (UC) contain activating PIK3CA mutations. In telomerase-immortalized normal urothelial cells (TERT-NHUC), ectopic expression of…”
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Advancing our understanding of skeletal muscle across the lifecourse: Protocol for the MASS_Lifecourse study and characteristics of the first 80 participants by Dodds, R.M., Hurst, C., Hillman, S.J., Davies, K., Roberts, L., Aspray, T.J., Granic, A., Sayer, A.A.

“…Sarcopenia, the age-related loss of skeletal muscle strength and mass, carries a significant burden for affected individuals. There has been little…”
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Heterozygous loss-of-function variants in DOCK4 cause neurodevelopmental delay and microcephaly by Herbst, Charlotte, Bothe, Viktoria, Wegler, Meret, Axer-Schaefer, Susanne, Audebert-Bellanger, Séverine, Gecz, Jozef, Cogne, Benjamin, Feldman, Hagit Baris, Horn, Anselm H. C., Hurst, Anna C. E., Kelly, Melissa A., Kruer, Michael C., Kurolap, Alina, Laquerriere, Annie, Li, Megan, Mark, Paul R., Morawski, Markus, Nizon, Mathilde, Pastinen, Tomi, Polster, Tilman, Saugier-Veber, Pascale, SeSong, Jang, Sticht, Heinrich, Stieler, Jens T., Thifffault, Isabelle, van Eyk, Clare L., Marcorelles, Pascale, Vezain-Mouchard, Myriam, Abou Jamra, Rami, Oppermann, Henry

“…Neurons form the basic anatomical and functional structure of the nervous system, and defects in neuronal differentiation or formation of neurites are…”
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Reactive skin decontamination lotion (RSDL) for the decontamination of chemical warfare agent (CWA) dermal exposure by Schwartz, M D, Hurst, C G, Kirk, M A, Reedy, S J D, Braue, Jr, E H

“…Rapid decontamination of the skin is the single most important action to prevent dermal absorption of chemical contaminants in persons exposed to chemical…”
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Return of non-ACMG recommended incidental genetic findings to pediatric patients: considerations and opportunities from experiences in genomic sequencing by Bowling, Kevin M, Thompson, Michelle L, Kelly, Melissa A, Scollon, Sarah, Slavotinek, Anne M, Powell, Bradford C, Kirmse, Brian M, Hendon, Laura G, Brothers, Kyle B, Korf, Bruce R, Cooper, Gregory M, Greally, John M, Hurst, Anna C E

“…The uptake of exome/genome sequencing has introduced unexpected testing results (incidental findings) that have become a major challenge for both testing…”
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Efficacy and Safety of Injectable Mixed Collagenase Subtypes in the Treatment of Dupuytren’s Contracture by Badalamente, Marie A., PhD, Hurst, Lawrence C., MD

“…Purpose To further evaluate the efficacy and safety of an injectable mixed subtype collagenase for the treatment of Dupuytren’s contracture (DC). Methods…”
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SU-G-IeP2-07: Investigation of 3D-Printed Phantoms for Synthetic CT Benchmarking in An MR-Only Workflow by Kim, J, Myers, E, Forbes, M, Chetty, I, Glide-Hurst, C

“…Purpose: As we move toward MR-only treatment planning, a need exists to develop multi-modality phantoms to benchmark synthetic CT (synCT) generation. We…”
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