Search Results - "Hurley, Arlene"

Evolution of antibody immunity to SARS-CoV-2 by Gaebler, Christian, Wang, Zijun, Lorenzi, Julio C. C., Muecksch, Frauke, Finkin, Shlomo, Tokuyama, Minami, Cho, Alice, Jankovic, Mila, Schaefer-Babajew, Dennis, Oliveira, Thiago Y., Cipolla, Melissa, Viant, Charlotte, Barnes, Christopher O., Bram, Yaron, Breton, Gaëlle, Hägglöf, Thomas, Mendoza, Pilar, Hurley, Arlene, Turroja, Martina, Gordon, Kristie, Millard, Katrina G., Ramos, Victor, Schmidt, Fabian, Weisblum, Yiska, Jha, Divya, Tankelevich, Michael, Martinez-Delgado, Gustavo, Yee, Jim, Patel, Roshni, Dizon, Juan, Unson-O’Brien, Cecille, Shimeliovich, Irina, Robbiani, Davide F., Zhao, Zhen, Gazumyan, Anna, Schwartz, Robert E., Hatziioannou, Theodora, Bjorkman, Pamela J., Mehandru, Saurabh, Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million individuals and is responsible for over 1.7 million deaths to date…”
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Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies by Barnes, Christopher O., West, Anthony P., Huey-Tubman, Kathryn E., Hoffmann, Magnus A.G., Sharaf, Naima G., Hoffman, Pauline R., Koranda, Nicholas, Gristick, Harry B., Gaebler, Christian, Muecksch, Frauke, Lorenzi, Julio C. Cetrulo, Finkin, Shlomo, Hägglöf, Thomas, Hurley, Arlene, Millard, Katrina G., Weisblum, Yiska, Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Bjorkman, Pamela J.

“…Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain (RBD) of the trimeric spike. Here, we characterized polyclonal…”
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Persistent cellular immunity to SARS-CoV-2 infection by Breton, Gaëlle, Mendoza, Pilar, Hägglöf, Thomas, Oliveira, Thiago Y, Schaefer-Babajew, Dennis, Gaebler, Christian, Turroja, Martina, Hurley, Arlene, Caskey, Marina, Nussenzweig, Michel C

“…SARS-CoV-2 is responsible for an ongoing pandemic that has affected millions of individuals around the globe. To gain further understanding of the immune…”
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Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico by Robbiani, Davide F., Bozzacco, Leonia, Keeffe, Jennifer R., Khouri, Ricardo, Olsen, Priscilla C., Gazumyan, Anna, Schaefer-Babajew, Dennis, Avila-Rios, Santiago, Nogueira, Lilian, Patel, Roshni, Azzopardi, Stephanie A., Uhl, Lion F.K., Saeed, Mohsan, Sevilla-Reyes, Edgar E., Agudelo, Marianna, Yao, Kai-Hui, Golijanin, Jovana, Gristick, Harry B., Lee, Yu E., Hurley, Arlene, Caskey, Marina, Pai, Joy, Oliveira, Thiago, Wunder, Elsio A., Sacramento, Gielson, Nery, Nivison, Orge, Cibele, Costa, Federico, Reis, Mitermayer G., Thomas, Neena M., Eisenreich, Thomas, Weinberger, Daniel M., de Almeida, Antonio R.P., West, Anthony P., Rice, Charles M., Bjorkman, Pamela J., Reyes-Teran, Gustavo, Ko, Albert I., MacDonald, Margaret R., Nussenzweig, Michel C.

“…Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in individuals who develop high titers of anti-ZIKV antibodies, we screened…”
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A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations by Wang, Qiao, Michailidis, Eleftherios, Yu, Yingpu, Wang, Zijun, Hurley, Arlene M., Oren, Deena A., Mayer, Christian T., Gazumyan, Anna, Liu, Zhenmi, Zhou, Yunjiao, Schoofs, Till, Yao, Kai-hui, Nieke, Jan P., Wu, Jianbo, Jiang, Qingling, Zou, Chenhui, Kabbani, Mohanmmad, Quirk, Corrine, Oliveira, Thiago, Chhosphel, Kalsang, Zhang, Qianqian, Schneider, William M., Jahan, Cyprien, Ying, Tianlei, Horowitz, Jill, Caskey, Marina, Jankovic, Mila, Robbiani, Davide F., Wen, Yumei, de Jong, Ype P., Rice, Charles M., Nussenzweig, Michel C.

“…Although there is no effective cure for chronic hepatitis B virus (HBV) infection, antibodies are protective and correlate with recovery from infection. To…”
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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals by Nussenzweig, Michel C, Scheid, Johannes F, Mouquet, Hugo, Feldhahn, Niklas, Seaman, Michael S, Velinzon, Klara, Pietzsch, John, Ott, Rene G, Anthony, Robert M, Zebroski, Henry, Hurley, Arlene, Phogat, Adhuna, Chakrabarti, Bimal, Li, Yuxing, Connors, Mark, Pereyra, Florencia, Walker, Bruce D, Wardemann, Hedda, Ho, David, Wyatt, Richard T, Mascola, John R, Ravetch, Jeffrey V

“…Antibodies to conserved epitopes on the human immunodeficiency virus (HIV) surface protein gp140 can protect against infection in non-human primates, and some…”
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Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein by Klein, Florian, Gaebler, Christian, Mouquet, Hugo, Sather, D Noah, Lehmann, Clara, Scheid, Johannes F, Kraft, Zane, Liu, Yan, Pietzsch, John, Hurley, Arlene, Poignard, Pascal, Feizi, Ten, Morris, Lynn, Walker, Bruce D, Fätkenheuer, Gerd, Seaman, Michael S, Stamatatos, Leonidas, Nussenzweig, Michel C

“…Two to three years after infection, a fraction of HIV-1-infected individuals develop serologic activity that neutralizes most viral isolates. Broadly…”
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Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening by Lalazar, Gadi, Requena, David, Ramos-Espiritu, Lavoisier, Ng, Denise, Bhola, Patrick D, de Jong, Ype P, Wang, Ruisi, Narayan, Nicole J C, Shebl, Bassem, Levin, Solomon, Michailidis, Eleftherios, Kabbani, Mohammad, Vercauteren, Koen O A, Hurley, Arlene M, Farber, Benjamin A, Hammond, William J, Saltsman, 3rd, James A, Weinberg, Ethan M, Glickman, J Fraser, Lyons, Barbara A, Ellison, Jessica, Schadde, Erik, Hertl, Martin, Leiting, Jennifer L, Truty, Mark J, Smoot, Rory L, Tierney, Faith, Kato, Tomoaki, Wendel, Hans-Guido, LaQuaglia, Michael P, Rice, Charles M, Letai, Anthony, Coffino, Philip, Torbenson, Michael S, Ortiz, Michael V, Simon, Sanford M

“…To repurpose therapeutics for fibrolamellar carcinoma (FLC), we developed and validated patient-derived xenografts (PDX) from surgical resections. Most agents…”
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Plasma microRNA Interindividual Variability in Healthy Individuals, Pregnant Women, and an Individual with a Stably Altered Neuroendocrine Phenotype by Max, Klaas E.A., Wang, Victoria R., Chang, Michael S., Liau, Jonathan, Weiss, Zachary R., Morgan, Stephanie, Li, Jenny, Bogardus, Kimberly A., Morozov, Pavel, Suryawanshi, Hemant, Akat, Kemal M., Ben-Dov, Iddo Z., Hurley, Arlene M., Dowd, Kathleen, Williams, Zev, Tuschl, Thomas

“…Abstract Background Extracellular RNAs (exRNAs) in biofluids are amenable to quantitative analysis and proposed as noninvasive biomarkers for monitoring organ…”
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In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers by Vasan, Sandhya, Hurley, Arlene, Schlesinger, Sarah J, Hannaman, Drew, Gardiner, David F, Dugin, Daniel P, Boente-Carrera, Mar, Vittorino, Roselle, Caskey, Marina, Andersen, Johanne, Huang, Yaoxing, Cox, Josephine H, Tarragona-Fiol, Tony, Gill, Dilbinder K, Cheeseman, Hannah, Clark, Lorna, Dally, Len, Smith, Carol, Schmidt, Claudia, Park, Harriet H, Kopycinski, Jakub T, Gilmour, Jill, Fast, Patricia, Bernard, Robert, Ho, David D

“…DNA-based vaccines have been safe but weakly immunogenic in humans to date. We sought to determine the safety, tolerability, and immunogenicity of ADVAX, a…”
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DRUL for school: Opening Pre-K with safe, simple, sensitive saliva testing for SARS-CoV-2 by Frank, Mayu O, Blachere, Nathalie E, Parveen, Salina, Hacisuleyman, Ezgi, Fak, John, Luna, Joseph M, Michailidis, Eleftherios, Wright, Samara, Stark, Pamela, Campbell, Ann, Foo, Ashley, Sakmar, Thomas P, Huffman, Virginia, Bergh, Marissa, Goldfarb, Audrey, Mansisidor, Andres, Patriotis, Agata L, Palmquist, Karl H, Poulton, Nicolas, Leicher, Rachel, Vargas, César D M, Duba, Irene, Hurley, Arlene, Colagreco, Joseph, Pagane, Nicole, Orange, Dana E, Mora, Kevin, Rakeman, Jennifer L, Fowler, Randal C, Fernandes, Helen, Lamendola-Essel, Michelle F, Didkovsky, Nicholas, Silvera, Leopolda, Masci, Joseph, Allen, Machelle, Rice, Charles M, Darnell, Robert B

“…To address the need for simple, safe, sensitive, and scalable SARS-CoV-2 tests, we validated and implemented a PCR test that uses a saliva collection kit use…”
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A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo by Markowitz, Martin, Louie, Michael, Hurley, Arlene, Sun, Eugene, Di Mascio, Michele, Perelson, Alan S, Ho, David D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Decay characteristics of HIV-1-infected compartments during combination therapy by Perelson, Alan S, Essunger, Paulina, Cao, Yunzhen, Vesanen, Mika, Hurley, Arlene, Saksela, Kalle, Markowitz, Martin, Ho, David D

“…Analysis of changes in viral load after initiation of treatment with potent antiretroviral agents has provided substantial insight into the dynamics of human…”
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4235 The Use of Checklists Throughout the Lifecourse of a Clinical Research Study: The Rockefeller University Checklist Suite by Brassil, Donna, Vaughan, Roger, Hurley, Arlene, Dowd, Kathleen, Hutt, Richard, Coller, Barry S.

“…OBJECTIVES/GOALS: We have developed a comprehensive Translational Research Navigation Program to guide investigators all the way from protocol development…”
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Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis by Ramratnam, Bharat, Bonhoeffer, Sebastian, Binley, James, Hurley, Arlene, Zhang, Linqi, Mittler, John E, Markowitz, M, Moore, John P, Perelson, Alan S, Ho, David D

“…In chronic HIV-1 infection, dynamic equilibrium exists between viral production and clearance. The half-life of free virions can be estimated by inhibiting…”
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Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine by Vasan, Sandhya, Schlesinger, Sarah J, Chen, Zhiwei, Hurley, Arlene, Lombardo, Angela, Than, Soe, Adesanya, Phumla, Bunce, Catherine, Boaz, Mark, Boyle, Rosanne, Sayeed, Eddy, Clark, Lorna, Dugin, Daniel, Boente-Carrera, Mar, Schmidt, Claudia, Fang, Qing, LeiBa, Huang, Yaoxing, Zaharatos, Gerasimos J, Gardiner, David F, Caskey, Marina, Seamons, Laura, Ho, Martin, Dally, Len, Smith, Carol, Cox, Josephine, Gill, Dilbinder, Gilmour, Jill, Keefer, Michael C, Fast, Patricia, Ho, David D

“…We conducted a Phase I dose-escalation trial of ADMVA, a Clade-B'/C-based HIV-1 candidate vaccine expressing env, gag, pol, nef, and tat in a modified vaccinia…”
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Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine by Vasan, Sandhya, Schlesinger, Sarah J, Huang, Yaoxing, Hurley, Arlene, Lombardo, Angela, Chen, Zhiwei, Than, Soe, Adesanya, Phumla, Bunce, Catherine, Boaz, Mark, Boyle, Rosanne, Sayeed, Eddy, Clark, Lorna, Dugin, Daniel, Schmidt, Claudia, Song, Yang, Seamons, Laura, Dally, Len, Ho, Martin, Smith, Carol, Markowitz, Martin, Cox, Josephine, Gill, Dilbinder K, Gilmour, Jill, Keefer, Michael C, Fast, Patricia, Ho, David D

“…We conducted a Phase I dose escalation trial of ADVAX, a DNA-based candidate HIV-1 vaccine expressing Clade C/B' env, gag, pol, nef, and tat genes. Sequences…”
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A Preliminary Study of Ritonavir, an Inhibitor of HIV-1 Protease, to Treat HIV-1 Infection by Markowitz, Martin, Saag, Michael, Powderly, William G, Hurley, Arlene M, Hsu, Ann, Valdes, Joaquin M, Henry, David, Sattler, Fred, Marca, Anthony La, Leonard, John M, Ho, David D

“…Antiretroviral therapy directed at the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1) has had limited success because of drug toxicity…”
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Neutralization Profiles of Newly Transmitted Human Immunodeficiency Virus Type 1 by Monoclonal Antibodies 2G12, 2F5, and 4E10 by MEHANDRU, Saurabh, WRIN, Terri, MARKOWITZ, Martin, GALOVICH, Justin, STIEGLER, Gabriela, VCELAR, Brigitta, HURLEY, Arlene, HOGAN, Christine, VASAN, Sandhya, KATINGER, Hermann, PETROPOULOS, Christos J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Rockefeller University Navigation Program: A Structured Multidisciplinary Protocol Development and Educational Program to Advance Translational Research by Brassil, Donna, Kost, Rhonda G., Dowd, Kathleen A., Hurley, Arlene M., Rainer, Tyler‐Lauren, Coller, Barry S.

“…The development of translational clinical research protocols is complex. To assist investigators, we developed a structured supportive guidance process…”
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