Search Results - "Hur, Stella K."

ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer by Somerville, Tim D. D., Xu, Yali, Wu, Xiaoli S., Maia-Silva, Diogo, Hur, Stella K., de Almeida, Larissa M. N., Preall, Jonathan B., Koo, Peter K., Vakoc, Christopher R.

“…Lineage plasticity is a prominent feature of pancreatic ductal adenocarcinoma (PDA) cells, which can occur via deregulation of lineage-specifying transcription…”
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Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation by Somerville, Tim Dd, Biffi, Giulia, Daßler-Plenker, Juliane, Hur, Stella K, He, Xue-Yan, Vance, Krysten E, Miyabayashi, Koji, Xu, Yali, Maia-Silva, Diogo, Klingbeil, Olaf, Demerdash, Osama E, Preall, Jonathan B, Hollingsworth, Michael A, Egeblad, Mikala, Tuveson, David A, Vakoc, Christopher R

“…A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we…”
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Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models by Chang, Suhee, Fulmer, Diana, Hur, Stella K, Thorvaldsen, Joanne L, Li, Li, Lan, Yemin, Rhon-Calderon, Eric A, Leu, Nicolae Adrian, Chen, Xiaowen, Epstein, Jonathan A, Bartolomei, Marisa S

“…Dysregulation of the imprinted locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal expression contributes to…”
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Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome by Chang, Suhee, Hur, Stella K., Naveh, Natali S. Sobel, Thorvaldsen, Joanne L., French, Deborah L., Gagne, Alyssa L, Jobaliya, Chintan D., Anguera, Montserrat C., Bartolomei, Marisa S., Kalish, Jennifer M

“…Genomic imprinting is a rare form of gene expression in mammals in which a small number of genes are expressed in a parent-of-origin-specific manner. The…”
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Tissue-specific and mosaic imprinting defects underlie opposite congenital growth disorders in mice by Freschi, Andrea, Hur, Stella K, Valente, Federica Maria, Ideraabdullah, Folami Y, Sparago, Angela, Gentile, Maria Teresa, Oneglia, Andrea, Di Nucci, Diego, Colucci-D'Amato, Luca, Thorvaldsen, Joanne L, Bartolomei, Marisa S, Riccio, Andrea, Cerrato, Flavia

“…Differential DNA methylation defects of H19/IGF2 are associated with congenital growth disorders characterized by opposite clinical pictures. Due to structural…”
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Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells by Himes, Blanca E, Obraztsova, Kseniya, Lian, Lurong, Shumyatcher, Maya, Rue, Ryan, Atochina-Vasserman, Elena N, Hur, Stella K, Bartolomei, Marisa S, Evans, Jilly F, Krymskaya, Vera P

“…Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in tuberous sclerosis complex 2 (TSC2), a…”
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Humanized H19/Igf2 locus reveals diverged imprinting mechanism between mouse and human and reflects Silver–Russell syndrome phenotypes by Hur, Stella K., Freschi, Andrea, Ideraabdullah, Folami, Thorvaldsen, Joanne L., Luense, Lacey J., Weller, Angela H., Berger, Shelley L., Cerrato, Flavia, Riccio, Andrea, Bartolomei, Marisa S.

“…Genomic imprinting affects a subset of genes in mammals, such that they are expressed in a monoallelic, parent-of-origin–specific manner. These genes are…”
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Abstract 1936: Epigenetic challenges in derivation of the first cell-based model of Beckwith-Wiedemann Syndrome by Hur, Stella K., Thorvaldsen, Joanne L., Chang, Suhee, Lye, Carolyn, Yu, Alice, Anguera, Monserrat C., Bartolomei, Marisa S., Kalish, Jennifer M.

“…Abstract Beckwith-Wiedemann Syndrome (BWS) is a cancer predisposition syndrome that affects at least 1 in 10,500 children. Up to 25% of children with BWS…”
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