Prediction of in-hospital mortality and morbidity using high-sensitivity C-reactive protein after burr hole craniostomy

Background The purpose of this study was to assess whether preanesthetic laboratory values can predict in-hospital mortality and morbidity in patients who have undergone burr hole craniostomy due to chronic subdural hematoma. Methods From January 2007 to February 2016, the records of 502 consecutive...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of anesthesia Vol. 30; no. 6; pp. 956 - 960
Main Authors:	Choi, Jung Ju, Kim, Hong Soon, Lee, Kyung Cheon, Hur, Hojin, Jo, Youn Yi
Format:	Journal Article
Language:	English
Published:	Tokyo Springer Japan 01-12-2016 Springer
Subjects:	Aged Aged, 80 and over Anesthesiology C-reactive protein C-Reactive Protein - metabolism Craniotomy - methods Critical Care Medicine Diagnosis Drainage - methods Emergency Medicine Female Hematoma, Subdural, Chronic - surgery Hospital Mortality Humans Intensive Male Measurement Medicine Medicine & Public Health Middle Aged Morbidity Multivariate Analysis Original Article Pain Medicine Patient outcomes Physiological aspects Prognosis Prothrombin Time Retrospective Studies Risk factors South Korea Burr hole craniostomy High-sensitivity C-reactive protein Chronic subdural hematoma Mortality Morbidity
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Background The purpose of this study was to assess whether preanesthetic laboratory values can predict in-hospital mortality and morbidity in patients who have undergone burr hole craniostomy due to chronic subdural hematoma. Methods From January 2007 to February 2016, the records of 502 consecutive patients who underwent burr hole craniotomy were analyzed. All cases of burr hole craniostomy were fitted with a drain, as required by our institutional protocol. Results Patients’ demographic data and preoperative laboratory values were subjected to logistic regression analysis to predict in-hospital mortality and morbidity after burr hole craniostomy. Hemoglobin, prothrombin time, activated partial thromboplastin time, serum glucose, and high-sensitivity C-reactive protein (hsCRP) were found to be significantly associated with in-hospital mortality and morbidity by univariate regression analysis, but of these, only hsCRP (hazard ratio 1.210, 95 % confidence interval 1.089–1.345, P < 0.001) was found to significantly predict in-hospital mortality and morbidity by multivariate regression analysis. Areas under the curve for predicting in-hospital mortality and morbidity were 0.765 (95 % confidence interval 0.624–0.906, P = 0.002) and 0.646 (0.559–0.733, P = 0.001), respectively. Conclusions Preoperative hsCRP was found to be an independent predictor of in-hospital mortality and morbidity after burr hole craniostomy due to chronic subdural hematoma.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0913-8668 1438-8359
DOI:	10.1007/s00540-016-2259-1