Search Results - "Hupe, Philippe"

Analysis of array CGH data: from signal ratio to gain and loss of DNA regions by Hupé, Philippe, Stransky, Nicolas, Thiery, Jean-Paul, Radvanyi, François, Barillot, Emmanuel

“…Motivation: Genomic DNA regions are frequently lost or gained during tumor progression. Array Comparative Genomic Hybridization (array CGH) technology makes it…”
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Multi-factor data normalization enables the detection of copy number aberrations in amplicon sequencing data by Boeva, Valentina, Popova, Tatiana, Lienard, Maxime, Toffoli, Sebastien, Kamal, Maud, Le Tourneau, Christophe, Gentien, David, Servant, Nicolas, Gestraud, Pierre, Rio Frio, Thomas, Hupé, Philippe, Barillot, Emmanuel, Laes, Jean-François

“…Because of its low cost, amplicon sequencing, also known as ultra-deep targeted sequencing, is now becoming widely used in oncology for detection of actionable…”
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miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death by GALLUZZI, Lorenzo, MORSELLI, Eugenia, RIPOCHE, Hugues, LAZAR, Vladimir, HAREL-BELLAN, Annick, DESSEN, Philippe, BARILLOT, Emmanuel, KROEMER, Guido, VITALE, Ilio, KEPP, Oliver, SENOVILLA, Laura, CRIOLLO, Alfredo, SERVANT, Nicolas, PACCARD, Caroline, HUPE, Philippe, ROBERT, Thomas

“…MicroRNAs (miRNA) are noncoding RNAs that regulate multiple cellular processes, including proliferation and apoptosis. We used microarray technology to…”
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Genomic Profiling and Identification of High-Risk Uveal Melanoma by Array CGH Analysis of Primary Tumors and Liver Metastases by Trolet, Julien, Hupe, Philippe, Huon, Isabelle, Lebigot, Ingrid, Decraene, Charles, Delattre, Olivier, Sastre-Garau, Xavier, Saule, Simon, Thiery, Jean-Paul, Plancher, Corine, Asselain, Bernard, Desjardins, Laurence, Mariani, Pascale, Piperno-Neumann, Sophie, Barillot, Emmanuel, Couturier, Jerome

“…Incurable metastases develop in approximately 50% of patients with uveal melanoma (UM). The purpose of this study was to analyze genomic profiles in a large…”
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NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes reverse phase protein array data by Troncale, Sylvie, Barbet, Aurélie, Coulibaly, Lamine, Henry, Emilie, He, Beilei, Barillot, Emmanuel, Dubois, Thierry, Hupé, Philippe, de Koning, Leanne

“…Reverse phase protein array (RPPA) is a powerful dot-blot technology that allows studying protein expression levels as well as post-translational modifications…”
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Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells by Marty, Bérengère, Maire, Virginie, Gravier, Eléonore, Rigaill, Guillem, Vincent-Salomon, Anne, Kappler, Marion, Lebigot, Ingrid, Djelti, Fathia, Tourdès, Audrey, Gestraud, Pierre, Hupé, Philippe, Barillot, Emmanuel, Cruzalegui, Francisco, Tucker, Gordon C, Stern, Marc-Henri, Thiery, Jean-Paul, Hickman, John A, Dubois, Thierry

“…Basal-like carcinomas (BLCs) and human epidermal growth factor receptor 2 overexpressing (HER2+) carcinomas are the subgroups of breast cancers that have the…”
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ART-DeCo: easy tool for detection and characterization of cross-contamination of DNA samples in diagnostic next-generation sequencing analysis by Fiévet, Alice, Bernard, Virginie, Tenreiro, Henrique, Dehainault, Catherine, Girard, Elodie, Deshaies, Vivien, Hupe, Philippe, Delattre, Olivier, Stern, Marc-Henri, Stoppa-Lyonnet, Dominique, Golmard, Lisa, Houdayer, Claude

“…Next-generation sequencing (NGS) is routinely used for constitutional genetic analysis. However, cross-contamination between samples constitutes a major risk…”
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Stability-based comparison of class discovery methods for DNA copy number profiles by Brito, Isabel, Hupé, Philippe, Neuvial, Pierre, Barillot, Emmanuel

“…Array-CGH can be used to determine DNA copy number, imbalances in which are a fundamental factor in the genesis and progression of tumors. The discovery of…”
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Multiple-checkpoint inhibition of thymic stromal lymphopoietin–induced TH2 response by TH17-related cytokines by Bogiatzi, Sofia I., Guillot-Delost, Maude, Cappuccio, Antonio, Bichet, Jean-Christophe, Chouchane-Mlik, Olfa, Donnadieu, Marie-Hélène, Barillot, Emmanuel, Hupé, Philippe, Chlichlia, Katerina, Efremidou, Eleni I., Aractingi, Selim, Bayrou, Olivier, Soumelis, Vassili

“…The interplay between allergy and autoimmunity has been a matter of long debate. Epidemiologic studies point to a decreased frequency of allergy in patients…”
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Proteomic screening identifies a YAP-driven signaling network linked to tumor cell proliferation in human schwannomas by Boin, Alizée, Couvelard, Anne, Couderc, Christophe, Brito, Isabel, Filipescu, Dan, Kalamarides, Michel, Bedossa, Pierre, De Koning, Leanne, Danelsky, Carine, Dubois, Thierry, Hupé, Philippe, Louvard, Daniel, Lallemand, Dominique

“…Inactivation of the NF2 gene predisposes to neurofibromatosis type II and the development of schwannomas. In vitro studies have shown that loss of NF2 leads to…”
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Influence of FLG loss-of-function mutations in host–microbe interactions during atopic skin inflammation by Oláh, Peter, Szlávicz, Eszter, Kuchner, Marcus, Nemmer, Jana, Zeeuwen, Patrick, Lefèvre-Utile, Alain, Fyhrquist, Nanna, Prast-Nielsen, Stefanie, Skoog, Tiina, Serra, Angela, Rodríguez, Elke, Raap, Ulrike, Meller, Stephan, Gyulai, Rolland, Hupé, Philippe, Kere, Juha, Levi-Schaffer, Francesca, Tsoka, Sophia, Alexander, Helen, Nestle, Frank O., Schröder, Jens M., Weidinger, Stephan, van den Bogaard, Ellen, Soumelis, Vassili, Greco, Dario, Barker, Jonathan, Lauerma, Antti, Ranki, Annamari, Andersson, Björn, Alenius, Harri, Homey, Bernhard

“…Loss-of-function mutations in the filaggrin (FLG) gene directly alter skin barrier function and critically influence atopic inflammation. While skin barrier…”
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Serum and Salivary IgG and IgA Response After COVID-19 Messenger RNA Vaccination by Gorochov, Guy, Ropers, Jacques, Launay, Odile, Dorgham, Karim, da Mata-Jardin, Omaira, Lebbah, Said, Durier, Christine, Bauer, Rebecca, Radenne, Anne, Desaint, Corinne, Vieillard, Louis-Victorien, Rekacewicz, Claire, Lachatre, Marie, Parfait, Béatrice, Batteux, Frédéric, Hupé, Philippe, Ninove, Läétitia, Lefebvre, Maeva, Conrad, Anne, Dussol, Bertrand, Maakaroun-Vermesse, Zoha, Melica, Giovanna, Nicolas, Jean-François, Verdon, Renaud, Kiladjian, Jean-Jacques, Loubet, Paul, Schmidt-Mutter, Catherine, Dualé, Christian, Ansart, Séverine, Botelho-Nevers, Elisabeth, Lelièvre, Jean-Daniel, de Lamballerie, Xavier, Kieny, Marie-Paule, Tartour, Eric, Paul, Stéphane

“…There is still considerable controversy in the literature regarding the capacity of intramuscular messenger RNA (mRNA) vaccination to induce a mucosal immune…”
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Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia by Ridinger-Saison, Maya, Boeva, Valentina, Rimmelé, Pauline, Kulakovskiy, Ivan, Gallais, Isabelle, Levavasseur, Benjamin, Paccard, Caroline, Legoix-Né, Patricia, Morlé, François, Nicolas, Alain, Hupé, Philippe, Barillot, Emmanuel, Moreau-Gachelin, Françoise, Guillouf, Christel

“…Acute leukemias are characterized by deregulation of transcriptional networks that control the lineage specificity of gene expression. The aberrant…”
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High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers by Bollet, Marc A., Servant, Nicolas, Neuvial, Pierre, Decraene, Charles, Lebigot, Ingrid, Meyniel, Jean-Philippe, De Rycke, Yann, Savignoni, Alexia, Rigaill, Guillem, Hupé, Philippe, Fourquet, Alain, Sigal-Zafrani, Brigitte, Barillot, Emmanuel, Thiery, Jean-Paul

“…Background To distinguish new primary breast cancers from true recurrences, pangenomic analyses of DNA copy number alterations (CNAs) using single-nucleotide…”
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Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice by Favaudon, Vincent, Caplier, Laura, Monceau, Virginie, Pouzoulet, Frédéric, Sayarath, Mano, Fouillade, Charles, Poupon, Marie-France, Brito, Isabel, Hupé, Philippe, Bourhis, Jean, Hall, Janet, Fontaine, Jean-Jacques, Vozenin, Marie-Catherine

“…In vitro studies suggested that sub-millisecond pulses of radiation elicit less genomic instability than continuous, protracted irradiation at the same total…”
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Corrigendum to ‘clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome’ by Scholl, Suzy, Popovic, Marina, Rochefordiere, Anne de la, Girard, Elodie, Dureau, Sylvain, Mandic, Aljosa, Koprivsek, Katarina, Samet, Nina, Craina, Marius, Margan, Madalin, Samuels, Sanne, Zijlmans, Henry, Kenter, Gemma, Hillemanns, Peter, Dema, Sorin, Dema, Alis, Malenkovic, Goran, Djuran, Branislav, Floquet, Anne, Garbay, Delphine, Guyon, Frédéric, Colombo, Pierre Emmanuel, Fabbro, Michel, Kerr, Christine, Ngo, Charlotte, Lecuru, Fabrice, del Campo, Eleonor Rivin, Coutant, Charles, Marchal, Frédéric, Mesgouez-Nebout, Nathalie, Fourchotte, Virginie, Feron, Jean Guillaume, Morice, Philippe, Deutsch, Eric, Wimberger, Pauline, Classe, Jean-Marc, Gleeson, Noreen, Leyen, Heiko von der, Minsat, Mathieu, Dubot, Coraline, Gestraud, Pierre, Kereszt, Attila, Nagy, Istvan, Balint, Balazs, Berns, Els, Jordanova, Ekaterina, de Saint-Jorre, Nicolas, Savignoni, Alexia, Servant, Nicolas, Hupe, Philippe, de Koning, Leanne, Fumoleau, Pierre, Rouzier, Roman, Kamal, Maud

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A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human T H -17 responses by Zollinger, Raphaël, Bogiatzi, Sofia I, Soumelis, Vassili, Hupé, Philippe, Volpe, Elisabetta, Servant, Nicolas, Barillot, Emmanuel

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Spatiotemporal control of interferon-induced JAK/STAT signalling and gene transcription by the retromer complex by Chmiest, Daniela, Sharma, Nanaocha, Zanin, Natacha, Viaris de Lesegno, Christine, Shafaq-Zadah, Massiullah, Sibut, Vonick, Dingli, Florent, Hupé, Philippe, Wilmes, Stephan, Piehler, Jacob, Loew, Damarys, Johannes, Ludger, Schreiber, Gideon, Lamaze, Christophe

“…Type-I interferons (IFNs) play a key role in the immune defences against viral and bacterial infections, and in cancer immunosurveillance. We have established…”
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Live-Cell Chromosome Dynamics and Outcome of X Chromosome Pairing Events during ES Cell Differentiation by Masui, Osamu, Bonnet, Isabelle, Le Baccon, Patricia, Brito, Isabel, Pollex, Tim, Murphy, Niall, Hupé, Philippe, Barillot, Emmanuel, Belmont, Andrew S., Heard, Edith

“…Random X inactivation represents a paradigm for monoallelic gene regulation during early ES cell differentiation. In mice, the choice of X chromosome to…”
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A comparison of Sars-Cov-2 vaccine platforms: the CoviCompare project by Molino, Diana, Durier, Christine, Radenne, Anne, Desaint, Corinne, Ropers, Jacques, Courcier, Soizic, Vieillard, Louis Victorien, Rekacewicz, Claire, Parfait, Beatrice, Appay, Victor, Batteux, Frédéric, Barillot, Emmanuel, Cogné, Michel, Combadière, Béhazine, Eberhardt, Christiane S., Gorochov, Guy, Hupé, Philippe, Ninove, Laetitia, Paul, Stéphane, Pellegrin, Isabelle, van der Werf, Sylvie, Lefebvre, Maeva, Botelho-Nevers, Elisabeth, Ortega-Perez, Inmaculada, Jaspard, Marie, Sow, Samba, Lelièvre, Jean Daniel, de Lamballerie, Xavier, Kieny, Marie Paule, Tartour, Eric, Launay, Odile

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