Search Results - "Huo, Meirong"

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel by Zhang, Yong, Huo, Meirong, Zhou, Jianping, Xie, Shaofei

“…Abstract This study presents PKSolver, a freely available menu-driven add-in program for Microsoft Excel written in Visual Basic for Applications (VBA), for…”
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Tumor-targeted delivery of sunitinib base enhances vaccine therapy for advanced melanoma by remodeling the tumor microenvironment by Huo, Meirong, Zhao, Yan, Satterlee, Andrew Benson, Wang, Yuhua, Xu, Ying, Huang, Leaf

“…Development of an effective treatment against advanced tumors remains a major challenge for cancer immunotherapy. We have previously developed a potent…”
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Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug by Huo, Meirong, Zhang, Yong, Zhou, Jianping, Zou, Aifeng, Yu, Di, Wu, Yiping, Li, Jing, Li, Hong

“…A new series of amphiphilically modified chitosan molecules with long alkyl chains as hydrophobic moieties and glycol groups as hydrophilic moieties…”
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Synthesis, characterization, drug-loading capacity and safety of novel octyl modified serum albumin micelles by Gong, Jian, Huo, Meirong, Zhou, Jianping, Zhang, Yong, Peng, Xiaoling, Yu, Di, Zhang, Hui, Li, Jing

“…A novel albumin derivative octyl modified serum albumin (OSA) which can form a core–shell structure in aqueous media by self-assembling due to core segregation…”
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Potential of amphiphilically modified low molecular weight chitosan as a novel carrier for hydrophobic anticancer drug: Synthesis, characterization, micellization and cytotoxicity evaluation by Zhang, Yong, Huo, Meirong, Zhou, Jianping, Yu, Di, Wu, Yiping

“…Amphiphilically modified low molecular weight chitosan (LMWC) with long chain alkyl groups as hydrophobic moieties and carboxymethyl groups as hydrophilic…”
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Formation, microstructure, biodistribution and absence of toxicity of polymeric micelles formed by N-octyl-N,O-carboxymethyl chitosan by Huo, Meirong, Zhang, Yong, Zhou, Jianping, Zou, Aifeng, Li, Jing

“…In this study, N-octyl-N,O-carboxymethyl chitosans (octyl-CM-Chitosan) with different molecular weights and degrees of alkylation were synthesized. The…”
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Enhanced oral absorption of paclitaxel in N-deoxycholic acid-N, O-hydroxyethyl chitosan micellar system by Li, Hong, Huo, Meirong, Zhou, Jianping, Dai, Yindi, Deng, Yaping, Shi, Xiangjie, Masoud, Jumah

“…The overall goal of this study was to develop a micellar system of paclitaxel (PTX) to enhance its oral absorption. An amphiphilic chitosan derivative,…”
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Dual Targeting of Cancer Cells and MMPs with Self-Assembly Hybrid Nanoparticles for Combination Therapy in Combating Cancer by Zhang, Kai, Li, Jingjing, Xin, Xiaofei, Du, Xiaoqing, Zhao, Di, Qin, Chao, Han, Xiaopeng, Huo, Meirong, Yang, Lei, Yin, Lifang

“…The co-delivery of chemotherapeutic agents and immune modulators to their targets remains to be a great challenge for nanocarriers. Here, we developed a hybrid…”
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Octreotide-modified N-octyl-O, N-carboxymethyl chitosan micelles as potential carriers for targeted antitumor drug delivery by Zou, Aifeng, Huo, Meirong, Zhang, Yong, Zhou, Jianping, Yin, Xiaoqiang, Yao, Chengli, Zhu, Qinnv, Zhang, Min, Ren, Jinshan, Zhang, Qiang

“…Octreotide (OCT) was recently found to have high binding affinity to the positive tumor cells of somatostatin receptors (SSTRs). In this study,…”
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Co-delivery of hydrophobic paclitaxel and hydrophilic AURKA specific siRNA by redox-sensitive micelles for effective treatment of breast cancer by Yin, Tingjie, Wang, Lei, Yin, Lifang, Zhou, Jianping, Huo, Meirong

“…Abstract In this study, a novel redox-sensitive micellar system constructed from a hyaluronic acid-based amphiphilic conjugate (HA-ss-(OA-g-bPEI), HSOP) was…”
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Co-delivery of silybin and paclitaxel by dextran-based nanoparticles for effective anti-tumor treatment through chemotherapy sensitization and microenvironment modulation by Huo, Meirong, Wang, Honglan, Zhang, Ying, Cai, Han, Zhang, Pan, Li, Lingchao, Zhou, Jianping, Yin, Tingjie

“…Modulation of tumor microenvironment (TME) has been indicated as an approach to improve efficacy of cancer therapy. Here, we proposed a nano co-delivery based…”
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Redox Sensitive Hyaluronic Acid‐Decorated Graphene Oxide for Photothermally Controlled Tumor‐Cytoplasm‐Selective Rapid Drug Delivery by Yin, Tingjie, Liu, Jiyong, Zhao, Zekai, Zhao, Yuanyuan, Dong, Lihui, Yang, Meng, Zhou, Jianping, Huo, Meirong

“…Nanocarriers capable of circumventing various biological barriers between the site of administration and the therapeutic target hold great potential for cancer…”
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DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles by Zhang, Yong, Huo, Meirong, Zhou, Jianping, Zou, Aifeng, Li, Weize, Yao, Chengli, Xie, Shaofei

“…In recent years, several mathematical models have been developed for analysis of drug dissolution data, and many different mathematical approaches have been…”
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Nanoparticle delivery of CDDO-Me remodels the tumor microenvironment and enhances vaccine therapy for melanoma by Zhao, Yan, Huo, Meirong, Xu, Zhenghong, Wang, Yuhua, Huang, Leaf

“…Abstract Lipid-calcium-phosphate nanoparticle (NP) delivery of Trp2 peptide vaccine is one of the most effective vaccine strategies against melanoma. However,…”
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A novel LDL-mimic nanocarrier for the targeted delivery of curcumin into the brain to treat Alzheimer's disease by Meng, Fanfei, Asghar, Sajid, Gao, Shiya, Su, Zhigui, Song, Jue, Huo, Meirong, Meng, Weidong, Ping, Qineng, Xiao, Yanyu

“…•A novel LDL-mimic nanocarrier (Lf-mNLC) was built for brain-targeted delivery.•The stability of Lf-mNLC in BCECs was evaluated through FRET analysis.•The…”
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Enhancing chemotherapy for pancreatic cancer through efficient and sustained tumor microenvironment remodeling with a fibroblast-targeted nanosystem by Zhou, Xinyuan, Zhang, Pan, Liu, Nan, Zhang, Xiao, Lv, Hui, Xu, Wei, Huo, Meirong

“…Pancreatic cancer (PC) carries a poor prognosis among all malignancies and poses great challenges to clinical drug accessibility due to the severely fibrotic…”
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Redox-sensitive micelles self-assembled from amphiphilic hyaluronic acid-deoxycholic acid conjugates for targeted intracellular delivery of paclitaxel by Li, Jing, Huo, Meirong, Wang, Jing, Zhou, Jianping, Mohammad, Jumah M, Zhang, Yinlong, Zhu, Qinnv, Waddad, Ayman Y, Zhang, Qiang

“…Abstract A targeted intracellular delivery system of paclitaxel (PTX) was successfully developed based on redox-sensitive hyaluronic acid-deoxycholic acid…”
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A pHe sensitive nanodrug for collaborative penetration and inhibition of metastatic tumors by Huo, Meirong, Zhou, Jiyuan, Wang, Honglan, Zheng, Yuzhao, Tong, Yuqing, Zhou, Jianping, Liu, Jiyong, Yin, Tingjie

“…Current chemotherapies for metastatic tumors are seriously restricted by limited drug infiltration and deficient disturbance of metastasis-associated complex…”
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Novel Chitosan Derivatives with Reversible Cationization and Hydrophobicization for Tumor Cytoplasm-Specific Burst Co-delivery of siRNA and Chemotherapeutics by Yin, Tingjie, Liu, Yanqi, Yang, Mengnan, Wang, Lei, Zhou, Jianping, Huo, Meirong

“…Despite the great potential of combination therapy based on siRNA and chemotherapeutics, an efficient vehicle with abilities of well drug co-loading,…”
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Somatostatin Receptor-Mediated Tumor-Targeting Nanocarriers Based on Octreotide-PEG Conjugated Nanographene Oxide for Combined Chemo and Photothermal Therapy by Zhang, Xuyuan, Yang, Chongyin, Zhou, Jianping, Huo, Meirong

“…Nano‐sized in vivo active targeting drug delivery systems have been developed to a high anti‐tumor efficacy strategy against certain cancer‐cells‐specific…”
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