Search Results - "Hunziker, Ernst"

The Elusive Path to Cartilage Regeneration by Hunziker, Ernst B.

“…Numerous attempts have been made to develop an efficacious strategy for the repair of articular cartilage. These endeavors have been undaunted, if not spurred,…”
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How best to preserve and reveal the structural intricacies of cartilaginous tissue by Hunziker, Ernst B., Lippuner, Kurt, Shintani, Nahoko

“…No single processing technique is capable of optimally preserving each and all of the structural entities of cartilaginous tissue. Hence, the choice of…”
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TGF-ß1 enhances the BMP-2-induced chondrogenesis of bovine synovial explants and arrests downstream differentiation at an early stage of hypertrophy by Shintani, Nahoko, Siebenrock, Klaus A, Hunziker, Ernst B

“…Synovial explants furnish an in-situ population of mesenchymal stem cells for the repair of articular cartilage. Although bone morphogenetic protein 2 (BMP-2)…”
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Hyaluronic Acid Promotes the Osteogenesis of BMP-2 in an Absorbable Collagen Sponge by Huang, Hairong, Feng, Jianying, Wismeijer, Daniel, Wu, Gang, Hunziker, Ernst B

“…(1) Background: We tested the hypothesis that hyaluronic acid (HA) can significantly promote the osteogenic potential of BMP-2/ACS (absorbable collagen…”
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The kinetics and mechanism of bone morphogenetic protein 2 release from calcium phosphate‐based implant‐coatings by Liu, Yuelian, Schouten, Corinne, Boerman, Otto, Wu, Gang, Jansen, John A., Hunziker, Ernst B.

“…Biomimetically deposited calcium phosphate‐based coatings of prostheses can serve as a vehicle for the targeted delivery of growth factors to the local implant…”
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The Acute Inflammatory Response to Absorbed Collagen Sponge Is Not Enhanced by BMP-2 by Huang, Hairong, Wismeijer, Daniel, Hunziker, Ernst B, Wu, Gang

“…Absorbed collagen sponge (ACS)/bone morphogenetic protein-2 (BMP-2) are widely used in clinical practise for bone regeneration. However, the application of…”
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Human Bone Typing Using Quantitative Cone-Beam Computed Tomography by Huang, Hairong, Chen, Dong, Lippuner, Kurt, Hunziker, Ernst B.

“…Bone typing is crucial to enable the choice of a suitable implant, the surgical technique, and the evaluation of the clinical outcome. Currently, bone typing…”
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In major joint diseases the human synovium retains its potential to form repair cartilage by Hunziker, Ernst B., Shintani, Nahoko, Lippuner, Kurt, Vögelin, Esther, Keel, Marius J. B.

“…The inner surface layer of human joints, the synovium, is a source of stem cells for the repair of articular cartilage defects. We investigated the potential…”
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Anticytokine Activity Enhances Osteogenesis of Bioactive Implants by Yang, Fan, Zhang, Xin, Huang, Hairong, Wu, Gang, Lippuner, Kurt, Hunziker, Ernst B

“…In dental clinical practice, systemic steroids are often applied at the end of implant surgeries to reduce postsurgical inflammation (tissue swelling, etc.)…”
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Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo by Klenke, Frank M., Liu, Yuelian, Yuan, Huipin, Hunziker, Ernst B., Siebenrock, Klaus A., Hofstetter, Willy

“…The repair of bone defects with biomaterials depends on a sufficient vascularization of the implantation site. We analyzed the effect of pore size on the…”
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Induced Experimental Peri-Implantitis and Periodontitis: What Are the Differences in the Inflammatory Response? by Huang, Hairon, Chen, Dong, Lippuner, Kurt, Hunziker, Ernst B.

“…This preliminary study investigates the differences between experimental periodontitis and peri-implantitis in a dog model, with a focus on the histopathology,…”
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Tenomodulin Is Necessary for Tenocyte Proliferation and Tendon Maturation by Docheva, Denitsa, Hunziker, Ernst B, Fässler, Reinhard, Brandau, Oliver

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Synovium of Human Osteoarthritic Joints Retains Its Chondrogenic Potential Irrespective of Age by Hunziker, Ernst B, Shintani, Nahoko, Haspl, Miroslav, Lippuner, Kurt, Vögelin, Esther, Keel, Marius J B

“…The autologous synovium is a potential tissue source for local induction of chondrogenesis by tissue engineering approaches to repair articular cartilage…”
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Current strategies for integrative cartilage repair by Boushell, Margaret K, Hung, Clark T, Hunziker, Ernst B, Strauss, Eric J, Lu, Helen H

“…Osteoarthritis (OA) is a degenerative joint condition characterized by painful cartilage lesions that impair joint mobility. Current treatments such as lavage,…”
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Crystalline Biomimetic Calcium Phosphate Coating on Mini-Pin Implants to Accelerate Osseointegration and Extend Drug Release Duration for an Orthodontic Application by Li, Menghong, Wu, Gang, Wang, Mingjie, Hunziker, Ernst B., Liu, Yuelian

“…Miniscrew implants (MSIs) have been widely used as temporary anchorage devices in orthodontic clinics. However, one of their major limitations is the…”
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Polymeric mesh and insulin‐like growth factor 1 delivery enhance cell homing and graft−cartilage integration by Boushell, Margaret K., Mosher, Christopher Z., Suri, Gurbani K., Doty, Stephen B., Strauss, Eric J., Hunziker, Ernst B., Lu, Helen H.

“…Cartilage injury, such as full‐thickness lesions, predisposes patients to the premature development of osteoarthritis, a degenerative joint disease. While…”
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The influence of BMP-2 and its mode of delivery on the osteoconductivity of implant surfaces during the early phase of osseointegration by Liu, Yuelian, Enggist, Lukas, Kuffer, Alexander F, Buser, Daniel, Hunziker, Ernst B

“…Abstract Osteogenic agents, such as bone morphogenetic protein-2 (BMP-2), can stimulate the degradation as well as the formation of bone. Hence, they could…”
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Cells, soluble factors and matrix harmonically play the concert of allograft integration by de Girolamo, Laura, Ragni, Enrico, Cucchiarini, Magali, van Bergen, Christian J. A., Hunziker, Ernst B., Chubinskaya, Susanna

“…Implantation of allograft tissues has massively grown over the last years, especially in the fields related to sports medicine. Beside the fact that often no…”
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Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development by Niebler, Stephan, Schubert, Thomas, Hunziker, Ernst B, Bosserhoff, Anja K

“…The transcription factor activating enhancer binding protein 2 epsilon (AP-2ε) was recently shown to be expressed during chondrogenesis as well as in articular…”
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Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function by Tsang, Kwok Yeung, Chan, Danny, Cheslett, Deborah, Chan, Wilson C W, So, Chi Leong, Melhado, Ian G, Chan, Tori W Y, Kwan, Kin Ming, Hunziker, Ernst B, Yamada, Yoshihiko, Bateman, John F, Cheung, Kenneth M C, Cheah, Kathryn S E

“…In protein folding and secretion disorders, activation of endoplasmic reticulum (ER) stress signaling (ERSS) protects cells, alleviating stress that would…”
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