Search Results - "Huntjens, Peter R"

Differentiating Electromechanical From Non-Electrical Substrates of Mechanical Discoordination to Identify Responders to Cardiac Resynchronization Therapy by Lumens, Joost, Tayal, Bhupendar, Walmsley, John, Delgado-Montero, Antonia, Huntjens, Peter R, Schwartzman, David, Althouse, Andrew D, Delhaas, Tammo, Prinzen, Frits W, Gorcsan, 3rd, John

“…Left ventricular (LV) mechanical discoordination, often referred to as dyssynchrony, is often observed in patients with heart failure regardless of QRS…”
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Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox by Daemen, Sabine, Gemmink, Anne, Brouwers, Bram, Meex, Ruth C.R., Huntjens, Peter R., Schaart, Gert, Moonen-Kornips, Esther, Jörgensen, Johanna, Hoeks, Joris, Schrauwen, Patrick, Hesselink, Matthijs K.C.

“…Intramyocellular lipid (IMCL) storage negatively associates with insulin resistance, albeit not in endurance-trained athletes. We investigated the putative…”
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Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5? by Gemmink, Anne, Daemen, Sabine, Brouwers, Bram, Huntjens, Peter R., Schaart, Gert, Moonen‐Kornips, Esther, Jörgensen, Johanna, Hoeks, Joris, Schrauwen, Patrick, Hesselink, Matthijs K. C.

“…Key points Intramyocellular lipid storage is negatively associated with insulin sensitivity. However, endurance trained athletes and type 2 diabetes mellitus…”
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The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach by Willemen, Erik, Schreurs, Rick, Huntjens, Peter R, Strik, Marc, Plank, Gernot, Vigmond, Edward, Walmsley, John, Vernooy, Kevin, Delhaas, Tammo, Prinzen, Frits W, Lumens, Joost

“…Timing of atrial, right (RV), and left ventricular (LV) stimulation in cardiac resynchronization therapy (CRT) is known to affect electrical activation and…”
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Prognostic Utility of Echocardiographic Atrial and Ventricular Strain Imaging in Patients With Cardiac Amyloidosis by Huntjens, Peter R., Zhang, Kathleen W., Soyama, Yuko, Karmpalioti, Maria, Lenihan, Daniel J., Gorcsan, John

“…The prognostic value of echocardiographic atrial and ventricular strain imaging in patients with biopsy-proven cardiac amyloidosis was assessed. Although left…”
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Cardiac electrical dyssynchrony is accurately detected by noninvasive electrocardiographic imaging by Bear, Laura R., Huntjens, Peter R., Walton, Richard D., Bernus, Olivier, Coronel, Ruben, Dubois, Rémi

“…Poor identification of electrical dyssynchrony is postulated to be a major factor contributing to the low success rate for cardiac resynchronization therapy…”
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Regional Work in Left Bundle Branch Block: A Balancing Act With Clinical Implications by Gorcsan, John, Huntjens, Peter R., Samii, Soraya

“…[Display omitted]…”
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Septal flash and septal rebound stretch have different underlying mechanisms by Walmsley, John, Huntjens, Peter R, Prinzen, Frits W, Delhaas, Tammo, Lumens, Joost

“…Abnormal left-right motion of the interventricular septum in early systole, known as septal flash (SF), is frequently observed in patients with left bundle…”
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Electrical Substrates Driving Response to Cardiac Resynchronization Therapy: A Combined Clinical–Computational Evaluation by Huntjens, Peter R, Ploux, Sylvain, Strik, Marc, Walmsley, John, Ritter, Philippe, Haissaguerre, Michel, Prinzen, Frits W, Delhaas, Tammo, Lumens, Joost, Bordachar, Pierre

“…BACKGROUND:The predictive value of interventricular versus intraventricular dyssynchrony for response to cardiac resynchronization therapy (CRT) remains…”
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Pacing therapy for atrioventricular dromotropathy: a combined computational-experimental-clinical study by Salden, Floor C W M, Huntjens, Peter R, Schreurs, Rick, Willemen, Erik, Kuiper, Marion, Wouters, Philippe, Maessen, Jos G, Bordachar, Pierre, Delhaas, Tammo, Luermans, Justin, Meine, Mathias, Allaart, Cornelis P, van Stipdonk, Antonius M W, Prinzen, Frits W, Lumens, Joost, Vernooy, Kevin

“…Investigate haemodynamic effects, and their mechanisms, of restoring atrioventricular (AV)-coupling using pacemaker therapy in normal and failing hearts in a…”
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Interim Analysis of the Phase II Study: Noninferiority Study of Doxorubicin with Upfront Dexrazoxane plus Olaratumab for Advanced or Metastatic Soft-Tissue Sarcoma by Van Tine, Brian A, Hirbe, Angela C, Oppelt, Peter, Frith, Ashley E, Rathore, Richa, Mitchell, Joshua D, Wan, Fei, Berry, Shellie, Landeau, Michele, Heberton, George A, Gorcsan, 3rd, John, Huntjens, Peter R, Soyama, Yoku, Vader, Justin M, Alvarez-Cardona, Jose A, Zhang, Kathleen W, Lenihan, Daniel J, Krone, Ronald J

“…To report the interim analysis of the phase II single-arm noninferiority trial, testing the upfront use of dexrazoxane with doxorubicin on progression-free…”
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Response to cardiac resynchronization therapy is determined by intrinsic electrical substrate rather than by its modification by Strik, Marc, Ploux, Sylvain, Huntjens, Peter R., Nguyên, Uyên Châu, Frontera, Antionio, Eschalier, Romain, Dubois, Remi, Ritter, Philippe, Klotz, Nicholas, Vernooy, Kevin, Haïssaguerre, Michel, Crijns, Harry J.G.M., Prinzen, Frits W., Bordachar, Pierre

“…Electrocardiographic mapping (ECM) expresses electrical substrate through magnitude and direction of the activation delay vector (ADV). We investigated to what…”
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Cardiovascular magnetic resonance features of mechanical dyssynchrony in patients with left bundle branch block by Revah, Giselle, Wu, Vincent, Huntjens, Peter R., Piekarski, Eve, Chyou, Janice Y., Axel, Leon

“…Patients with left bundle branch block (LBBB) can exhibit mechanical dyssynchrony which may contribute to heart failure; such patients may benefit from cardiac…”
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Influence of left ventricular lead position relative to scar location on response to cardiac resynchronization therapy: a model study by Huntjens, Peter R, Walmsley, John, Ploux, Sylvain, Bordachar, Pierre, Prinzen, Frits W, Delhaas, Tammo, Lumens, Joost

“…It is unclear how the position of the left ventricular (LV) lead relative to a scar affects the haemodynamic response in patients with dyssynchronous heart…”
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Regional Work in Left Bundle Branch Block by Gorcsan, John, Huntjens, Peter R., Samii, Soraya

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Interim analysis of the Phase II Study: Non-Inferiority Study of Doxorubicin with Upfront Dexrazoxane plus Olaratumab for Advanced or Metastatic Soft Tissue Sarcoma by Van Tine, Brian A., Hirbe, Angela C., Oppelt, Peter, Frith, Ashley E., Rathore, Richa, Mitchell, Joshua D., Wan, Fei, Berry, Shellie, Landeau, Michele, Heberton, George A., Gorcsan, John, Huntjens, Peter R., Soyama, Yoku, Vader, Justin M., Alvarez-Cardona, Jose A., Zhang, Kathleen W., Lenihan, Daniel J., Krone, Ronald J.

“…Anthracyclines are the front-line treatment for STS. Standard of care is to initiate dexrazoxane after a cumulative dose of 300 mg/m 2 of doxorubicin or to…”
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Virtual patient simulations for cardiology education and research: A CircAdapt perspective by Trifonov, Dimitar, Huntjens, Peter, Willemen, Erik, Delhaas, Tammo, Lumens, Joost

“…Nowadays cardiac simulations are becoming increasingly sophisticated. This trend, part of the maturing field of computational medicine, has provided medical…”
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