Search Results - "Hunter, Zoe"
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A Biodegradable Nanoparticle Platform for the Induction of Antigen-Specific Immune Tolerance for Treatment of Autoimmune Disease
Published in ACS nano (25-03-2014)“…Targeted immune tolerance is a coveted therapy for the treatment of a variety of autoimmune diseases, as current treatment options often involve nonspecific…”
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Biodegradable antigen-associated PLG nanoparticles tolerize Th2-mediated allergic airway inflammation pre- and postsensitization
Published in Proceedings of the National Academy of Sciences - PNAS (03-05-2016)“…Specific immunotherapy (SIT) is the most widely used treatment for allergic diseases that directly targets the T helper 2 (Th2) bias underlying allergy…”
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Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
Published in Nature biotechnology (01-12-2012)“…Microparticles coated with encephalitogenic peptides are effective at treating multiple sclerosis in a mouse model. Aberrant T-cell activation underlies many…”
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Ataxia Telangiectasia patient-derived neuronal and brain organoid models reveal mitochondrial dysfunction and oxidative stress
Published in Neurobiology of disease (01-09-2024)“…Ataxia Telangiectasia (AT) is a rare disorder caused by mutations in the ATM gene and results in progressive neurodegeneration for reasons that remain poorly…”
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Targeting the GM-CSF receptor for the treatment of CNS autoimmunity
Published in Journal of autoimmunity (01-11-2017)“…Abstract In multiple sclerosis (MS), there is a growing interest in inhibiting the pro-inflammatory effects of granulocyte-macrophage colony-stimulating factor…”
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Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening
Published in Stem cell research (01-04-2022)“…In this paper, we describe the generation and validation of human induced pluripotent stem cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs)…”
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Use of Facebook as part of a social media strategy for patient engagement
Published in Canadian family physician (01-03-2017)Get full text
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Generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells of three drug resistant and three drug responsive epilepsy patients
Published in Stem cell research (01-10-2021)“…Epilepsy is a common neurological disorder characterized by seizures. Unfortunately, 30–40% of all epilepsy patients are resistant to at least two or more…”
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Reprogramming of human olfactory neurosphere-derived cells from olfactory mucosal biopsies of a control cohort
Published in Stem cell research (01-10-2021)“…Human olfactory neurosphere-derived (ONS) cells are derived from the olfactory mucosa and display some progenitor- and neuronal cell-like properties, making…”
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Ataxia Telangiectasia iPSC line generated from a patient olfactory biopsy identifies novel disease-causing mutations
Published in Stem cell research (01-10-2021)“…Ataxia Telangiectasia is a rare autosomal recessive disorder caused by a mutated ATM gene. The most debilitating symptom of Ataxia Telangiectasia is the…”
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Optical tomographic imaging of near infrared imaging agents quantifies disease severity and immunomodulation of experimental autoimmune encephalomyelitis in vivo
Published in Journal of neuroinflammation (15-11-2013)“…Experimental autoimmune encephalomyelitis (EAE) is an animal model that captures many of the hallmarks of human multiple sclerosis (MS), including blood-brain…”
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Targeted immunomodulation using antigen-conjugated nanoparticles
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-05-2014)“…ABSTRACT The growing prevalence of nanotechnology in the fields of biology, medicine, and the pharmaceutical industry is confounded by the relatively small…”
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Intravenous immune-modifying nanoparticles as a therapy for spinal cord injury in mice
Published in Neurobiology of disease (01-12-2017)“…Intravenously infused synthetic 500nm nanoparticles composed of poly(lactide-co-glycolide) are taken up by blood-borne inflammatory monocytes via a macrophage…”
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A Vaccine against CCR5 Protects a Subset of Macaques upon Intravaginal Challenge with Simian Immunodeficiency Virus SIVmac251
Published in Journal of Virology (01-02-2014)“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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15
Alcohol, Health, and Injuries
Published in American journal of lifestyle medicine (01-07-2013)“…Although alcohol has existed almost as long as human existence, its consumption and abuse can have many detrimental effects. Alcohol has been associated with a…”
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Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis
Published in Nature biotechnology (01-06-2013)Get full text
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17
Facing the consequences of binge drinking
Published in Canadian family physician (01-10-2013)Get full text
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Visual half-field experiments are a good measure of cerebral language dominance if used properly: Evidence from fMRI
Published in Neuropsychologia (2008)“…Traditional neuropsychology employs visual half-field (VHF) experiments to assess cerebral language dominance. This approach is based on the assumption that…”
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Hemispheric asymmetry affects foveal word reading
Published in Brain and cognition (01-06-2008)Get full text
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" Hitting the spot ": Developing individuals with lived-experience of health and social care as facilitators to deliver a course to enhance public involvement in research - a Welsh perspective
Published in Research involvement and engagement (04-04-2017)“…Public involvement in research has become an important and integral part of the research process in health and social care, from the early stages of research…”
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