Search Results - "Hunter, Z R"

Characterization of familial Waldenstrom's macroglobulinemia by TREON, S. P, HUNTER, Z. R, TOURNILHAC, O, PATTERSON, C. J, MANNING, R, BRANAGAN, A. R, MORTON, C. C, AGGARWAL, A, EWEN, E. P, MASOTA, S, LEE, C, DITZEL SANTOS, D, HATJIHARISSI, E, XU, L, LELEU, X

“…Familial clustering of B-cell disorders among Waldenström's macroglobulinemia (WM) patients has been reported, though the frequency and any differences in…”
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The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia by Cao, Y, Hunter, Z R, Liu, X, Xu, L, Yang, G, Chen, J, Patterson, C J, Tsakmaklis, N, Kanan, S, Rodig, S, Castillo, J J, Treon, S P

“…CXCR4(WHIM) somatic mutations are common Waldenstrom's Macroglobulinemia (WM), and are associated with clinical resistance to ibrutinib. We engineered WM cells…”
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Volatile fatty acid profile for grass hay or alfalfa hay fed to alpacas (Vicugna pacos) by Oldham, C. L, Robinson, T. F, Hunter, Z. R, Taylor, L, White, J, Johnston, N. P

“…The purpose of this study was to determine the diurnal composition and concentration of volatile fatty acids (VFA) and to determine VFA composition and…”
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ERK1/2 pro‐survival signalling is suppressed by pirtobrutinib in ibrutinib‐resistant MYD88‐mutated lymphoma cells by Munshi, M., Liu, X., Kofides, A., Tsakmaklis, N., Hunter, Z. R., Guerrera, M. L., Canning, A., Gustine, J. N., Liu, S., Hatcher, J. M., Chen, J., Meid, K., Sarosiek, S., Flynn, C. A., Branagan, A. R., Keudell, G., Palomba, L. M., Castillo, J. J., Yang, G., Treon, S. P.

“…Summary Covalent Bruton's tyrosine kinase‐inhibitors (cBTK‐i) are highly active in MYD88‐mutated (MYD88Mut) Waldenstrom's macroglobulinaemia and suppress…”
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Detection of MYD88 L265P in peripheral blood of patients with Waldenström’s Macroglobulinemia and IgM monoclonal gammopathy of undetermined significance by Xu, L, Hunter, Z R, Yang, G, Cao, Y, Liu, X, Manning, R, Tripsas, C, Chen, J, Patterson, C J, Kluk, M, Kanan, S, Castillo, J, Lindeman, N, Treon, S P

“…MYD88 L265P is highly prevalent in Waldenstrom’s Macroglobulinemia (WM) and IgM monoclonal gammopathy of unknown significance (MGUS). We investigated whether…”
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Report of Consensus Panel 3 from the 11th International workshop on Waldenström's Macroglobulinemia: Recommendations for molecular diagnosis in Waldenström's Macroglobulinemia by Garcia-Sanz, Ramón, Varettoni, Marzia, Jiménez, Cristina, Ferrero, Simone, Poulain, Stephanie, San-Miguel, Jesus F., Guerrera, Maria L., Drandi, Daniela, Bagratuni, Tina, McMaster, Mary, Roccaro, Aldo M., Roos-Weil, Damien, Leiba, Merav, Li, Yong, Qiu, Luigi, Hou, Jian, De Larrea, C. Fernandez, Castillo, Jorge J., Dimopoulos, M., Owen, R.G., Treon, S.P., Hunter, Z.R.

“…Apart from the MYD88L265P mutation, extensive information exists on the molecular mechanisms in Waldenström's Macroglobulinemia and its potential utility in…”
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Clonal B cells in Waldenström’s macroglobulinemia exhibit functional features of chronic active B-cell receptor signaling by Argyropoulos, K V, Vogel, R, Ziegler, C, Altan-Bonnet, G, Velardi, E, Calafiore, M, Dogan, A, Arcila, M, Patel, M, Knapp, K, Mallek, C, Hunter, Z R, Treon, S P, van den Brink, M R M, Palomba, M L

“…Waldenström’s macroglobulinemia (WM) is a B-cell non-Hodgkin’s lymphoma (B-NHL) characterized by immunoglobulin M (IgM) monoclonal gammopathy and the medullary…”
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miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth by Fulciniti, M, Amodio, N, Bandi, R L, Cagnetta, A, Samur, M K, Acharya, C, Prabhala, R, D'Aquila, P, Bellizzi, D, Passarino, G, Adamia, S, Neri, A, Hunter, Z R, Treon, S P, Anderson, K C, Tassone, P, Munshi, N C

“…Deregulated microRNA (miR)/transcription factor (TF)-based networks represent a hallmark of cancer. We report here a novel c-Myc/miR-23b/Sp1 feed-forward loop…”
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The WHIM-like CXCR4S338X somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom’s Macroglobulinemia by Cao, Y, Hunter, Z R, Liu, X, Xu, L, Yang, G, Chen, J, Patterson, C J, Tsakmaklis, N, Kanan, S, Rodig, S, Castillo, J J, Treon, S P

“…CXCR4 WHIM somatic mutations are common Waldenstrom’s Macroglobulinemia (WM), and are associated with clinical resistance to ibrutinib. We engineered WM cells…”
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The WHIM-like CXCR4.sup.S338X somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia by Yang, G, Xu, L, Cao, Y, Patterson, C J, Hunter, Z R, Liu, X, Chen, J

“…CXCR4.sup.WHIM somatic mutations are common Waldenstrom's Macroglobulinemia (WM), and are associated with clinical resistance to ibrutinib. We engineered WM…”
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The WHIM-like CXCR4 super(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia by Cao, Y, Hunter, Z R, Liu, X, Xu, L, Yang, G, Chen, J, Patterson, C J, Tsakmaklis, N, Kanan, S, Rodig, S, Castillo, J J, Treon, S P

“…CXCR4 super(WHIM) somatic mutations are common Waldenstrom's Macroglobulinemia (WM), and are associated with clinical resistance to ibrutinib. We engineered WM…”
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Foveal word reading requires interhemispheric communication by Hunter, Zoë R, Brysbaert, Marc, Knecht, Stefan

“…The left cerebral hemisphere is dominant for language processing in most individuals. It has been suggested that this asymmetric language representation can…”
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IBRUTINIB MONOTHERAPY PRODUCES LONG‐TERM DISEASE CONTROL IN PREVIOUSLY TREATED WALDENSTROM'S MACROGLOBULINEMIA. FINAL REPORT OF THE PIVOTAL TRIAL (NCT01614821) by Treon, S.P., Meid, K., Gustine, J., Yang, G., Xu, L., Patterson, C.J., Ghobrial, I., Laubach, J.P., Hunter, Z.R., Dubeau, T., Palomba, L., Advani, R., Castillo, J.J.

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IgA and IgG hypogammaglobulinemia in Waldenström’s macroglobulinemia by Hunter, Zachary R, Manning, Robert J, Hanzis, Christine, Ciccarelli, Bryan T, Ioakimidis, Leukothea, Patterson, Christopher J, Lewicki, Megan C, Tseng, Hsuiyi, Gong, Ping, Liu, Xia, Zhou, Yangsheng, Yang, Guang, Sun, Jenny, Xu, Lian, Sheehy, Patricia, Morra, Massimo, Treon, Steven P

“…Hypogammaglobulinemia is common in Waldenström's macroglobulinemia. The etiology of this finding remains unclear, but it has been speculated to be based on…”
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Association of familial disease status with inferior treatment outcome in patients with Waldenstrom’s macroglobulinemia by Hunter, Z. R., Hanzis, C., Ioakimidis, L., Tripsas, C., Manning, R. J., Patterson, C. J., Sheehy, P., Turnbull, B., Treon, S. P.

“…Abstract only…”
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Site-specific relative risks of second primary malignancies among patients with Waldenstrom macroglobulinemia by Brown Philpot, L. M., Ojha, R. P., Felini, M. J., Treon, S. P., Hanzis, C. A., Hunter, Z. R., Thertulien, R.

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Long-term follow-up of patients with lymphoplasmacytic lymphoma (Waldenstrom's macroglobulinemia) who were treated with alemtuzumab by Soumerai, J. D., Hunter, Z. R., Boxer, M., Kahl, B. S., Ioakimidis, L. I., Patterson, C. J., Treon, S. P.

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Activity of the CD20-directed monoclonal antibody GA101 relative to rituximab in Waldenstrom's macroglobulinemia (WM), and applicability to patients expressing FcγRIIIA-158 F/F by Yang, G., Gong, P., Xu, L., Hunter, Z. R., Zhou, Y., Liu, X., Cao, Y., Ciccarelli, B., Patterson, C. J., Treon, S. P.

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Clinical characteristics and treatment outcome of disease-related peripheral neuropathy in Waldenstrom's macroglobulinemia (WM) by Treon, S. P., Hanzis, C. A., Ioakimidis, L. I., Patterson, C. J., Hunter, Z. R., Brodsky, P. S., Sheehy, P. S., Manning, R. J.

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Activity of the NEDD8-specific inhibitor MLN 4924 in multiple myeloma and Waldenström's macroglobulinemia, and effect on miRNA expression by McMillin, D. W., Hunter, Z. R., Delmore, J., Smith, P., Birner, A., Richardson, P. G., Anderson, K. C., Treon, S. P., Mitsiades, C. S.

“…Abstract only…”
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