Search Results - "Hunter, Monte"
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Extracellular vesicles in the pathogenesis of rheumatoid arthritis and osteoarthritis
Published in Arthritis research & therapy (01-12-2016)“…Osteoarthritis (OA) and rheumatoid arthritis (RA) are both debilitating diseases that cause significant morbidity in the US population. Extracellular vesicles…”
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Emerging role of extracellular vesicles in musculoskeletal diseases
Published in Molecular aspects of medicine (01-04-2018)“…Research into the biology of extracellular vesicles (EVs), including exosomes and microvesicles, has expanded significantly with advances in EV isolation…”
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Recent advances in hyaluronic acid based therapy for osteoarthritis
Published in Clinical and translational medicine (16-02-2018)“…Osteoarthritis is a debilitating disease that has increased in prevalence across the world due to the aging population. Currently, physicians use a plethora of…”
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Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis
Published in Scientific reports (17-05-2017)“…The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches are limited to preventing progression of the disease. Recent studies…”
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Advances in Molecular biomarker for early diagnosis of Osteoarthritis
Published in Biomolecular concepts (09-08-2019)“…Osteoarthritis (OA) is a chronic degenerative joint disease. The pathogenesis is poorly understood. What is known is that OA is characterized by imbalance in…”
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Pros and cons of mouse models for studying osteoarthritis
Published in Clinical and translational medicine (21-11-2018)“…Osteoarthritis (OA) is one of the most common chronic conditions in the world today. It results in breakdown of cartilage in joints and causes the patient to…”
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Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics
Published in Stem cells international (01-01-2016)“…Within the field of regenerative medicine, many have sought to use stem cells as a promising way to heal human tissue; however, in the past few years, exosomes…”
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Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview
Published in Mechanisms of ageing and development (01-03-2019)“…•MIRNA-141 plays a vital role in stem cell senescence.•MIRNA-141 negatively regulated stem cell differentiation.•Oxidative and inflammatory stress factors…”
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Sex-Specific Differences in Extracellular Vesicle Protein Cargo in Synovial Fluid of Patients with Osteoarthritis
Published in Life (Basel, Switzerland) (10-12-2020)“…Women are at a significantly higher risk of developing osteoarthritis (OA) compared to males. The pathogenesis of osteoarthritis (OA) in women is poorly…”
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MicroRNAs-141 and 200a regulate the SVCT2 transporter in bone marrow stromal cells
Published in Molecular and cellular endocrinology (15-07-2015)“…•Mouse BMSCs express miR-141 and miR-200a.•MiR-141 and miR-200a repressed SVCT2 expression by targeting the 3′-UTR of mRNA.•MiR-141 and miR-200a decrease…”
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Effects of femoral tunnel placement on knee laxity and forces in an anterior cruciate ligament graft
Published in Journal of orthopaedic research (01-09-2002)“…The purpose of this study was to measure the effects of variation in placement of the femoral tunnel upon knee laxity, graft pretension required to restore…”
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Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
Published in Life (Basel, Switzerland) (22-02-2023)“…Osteoarthritis (OA) is a highly prevalent degenerative joint condition that disproportionately affects females. The pathophysiology of the disease is not well…”
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Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment
Published in Stem cells international (01-01-2019)“…The aim of this study is to review all the published clinical trials on autologous bone marrow mesenchymal stem cells (BM-MSCs) in the repair of cartilage…”
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Modulation of miRNAs by Vitamin C in Human Bone Marrow Stromal Cells
Published in Nutrients (08-02-2018)“…MicroRNAs (miRNAs) are small (18-25 nucleotides), noncoding RNAs that have been identified as potential regulators of bone marrow stromal cell (BMSC)…”
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The crucial role of vitamin C and its transporter (SVCT2) in bone marrow stromal cell autophagy and apoptosis
Published in Stem cell research (01-09-2015)“…Vitamin C is an antioxidant that plays a vital role in various biological processes including bone formation. Previously, we reported that vitamin C is…”
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Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells
Published in Bone Reports (01-06-2020)“…Mechanisms leading to age-related reductions in bone formation and subsequent osteoporosis are still incompletely understood. We recently demonstrated that…”
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Biomechanical Effects of Femoral Notchplasty in Anterior Cruciate Ligament Reconstruction
Published in The American journal of sports medicine (01-01-2002)“…Notchplasty is frequently performed in conjunction with anterior cruciate ligament reconstruction. Bench loading tests were performed on 26 fresh-frozen knee…”
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Ankle flexibility and injury patterns in dancers
Published in The American journal of sports medicine (01-11-1996)“…Lower-extremity injuries are common among dancers and cause significant absences from rehearsals and performances. For this study of lower-extremity injuries…”
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Effects of notchplasty and femoral tunnel position on excursion patterns of an anterior cruciate ligament graft
Published in Arthroscopy (01-04-2003)“…Purpose: Errors in femoral tunnel placement in anterior cruciate ligament (ACL) reconstruction can cause excessive length changes in the graft during knee…”
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MicroRNA-141-3p Negatively Modulates SDF-1 Expression in Age-Dependent Pathophysiology of Human and Murine Bone Marrow Stromal Cells
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (16-08-2019)“…Abstract Stromal cell-derived factor-1 (SDF-1 or CXCL12) is a cytokine secreted by cells including bone marrow stromal cells (BMSCs). SDF-1 plays a vital role…”
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