Search Results - "Hunter, C. Neil"
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Biosynthesis of the modified tetrapyrroles—the pigments of life
Published in The Journal of biological chemistry (15-05-2020)“…Modified tetrapyrroles are large macrocyclic compounds, consisting of diverse conjugation and metal chelation systems and imparting an array of colors to the…”
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Generalized biomolecular modeling and design with RoseTTAFold All-Atom
Published in Science (American Association for the Advancement of Science) (19-04-2024)“…Deep-learning methods have revolutionized protein structure prediction and design but are presently limited to protein-only systems. We describe RoseTTAFold…”
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Protochlorophyllide synthesis by recombinant cyclases from eukaryotic oxygenic phototrophs and the dependence on Ycf54
Published in Biochemical journal (26-06-2020)“…The unique isocyclic E ring of chlorophylls contributes to their role as light-absorbing pigments in photosynthesis. The formation of the E ring is catalyzed…”
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Cryo-EM structure of the dimeric Rhodobacter sphaeroides RC-LH1 core complex at 2.9 Å: the structural basis for dimerisation
Published in Biochemical journal (12-11-2021)“…The dimeric reaction centre light-harvesting 1 (RC-LH1) core complex of Rhodobacter sphaeroides converts absorbed light energy to a charge separation, and then…”
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Cryo-EM Structure of the Rhodobacter sphaeroides Light-Harvesting 2 Complex at 2.1 Å
Published in Biochemistry (Easton) (09-11-2021)“…Light-harvesting 2 (LH2) antenna complexes augment the collection of solar energy in many phototrophic bacteria. Despite its frequent role as a model for such…”
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A photosynthetic antenna complex foregoes unity carotenoid-to-bacteriochlorophyll energy transfer efficiency to ensure photoprotection
Published in Proceedings of the National Academy of Sciences - PNAS (24-03-2020)“…Carotenoids play a number of important roles in photosynthesis, primarily providing light-harvesting and photoprotective energy dissipation functions within…”
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Extensive remodeling of the photosynthetic apparatus alters energy transfer among photosynthetic complexes when cyanobacteria acclimate to far-red light
Published in Biochimica et biophysica acta. Bioenergetics (01-04-2020)“…Some cyanobacteria remodel their photosynthetic apparatus by a process known as Far-Red Light Photoacclimation (FaRLiP). Specific subunits of the phycobilisome…”
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Overall energy conversion efficiency of a photosynthetic vesicle
Published in eLife (26-08-2016)“…The chromatophore of purple bacteria is an intracellular spherical vesicle that exists in numerous copies in the cell and that efficiently converts sunlight…”
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Three classes of oxygen-dependent cyclase involved in chlorophyll and bacteriochlorophyll biosynthesis
Published in Proceedings of the National Academy of Sciences - PNAS (13-06-2017)“…The biosynthesis of (bacterio)chlorophyll pigments is among the most productive biological pathways on Earth. Photosynthesis relies on these modified…”
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Excitation energy transfer in proteoliposomes reconstituted with LH2 and RC-LH1 complexes from Rhodobacter sphaeroides
Published in Bioscience reports (01-02-2024)“…Light-harvesting 2 (LH2) and reaction-centre light-harvesting 1 (RC-LH1) complexes purified from the photosynthetic bacterium Rhodobacter (Rba.) sphaeroides…”
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Integration of energy and electron transfer processes in the photosynthetic membrane of Rhodobacter sphaeroides
Published in Biochimica et biophysica acta (01-10-2014)“…Photosynthesis converts absorbed solar energy to a protonmotive force, which drives ATP synthesis. The membrane network of chlorophyll–protein complexes…”
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The structure and assembly of reaction centre-light-harvesting 1 complexes in photosynthetic bacteria
Published in Bioscience reports (31-05-2023)“…Chlorophototrophic organisms have a charge-separating reaction centre (RC) complex that receives energy from a dedicated light-harvesting (LH) antenna. In the…”
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Progress and challenges in engineering cyanobacteria as chassis for light‐driven biotechnology
Published in Microbial biotechnology (01-03-2020)“…Summary Cyanobacteria are prokaryotic phototrophs that, in addition to being excellent model organisms for studying photosynthesis, have tremendous potential…”
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Lateral Segregation of Photosystem I in Cyanobacterial Thylakoids
Published in The Plant cell (01-05-2017)“…Photosystem I (PSI) is the dominant photosystem in cyanobacteria and it plays a pivotal role in cyanobacterial metabolism. Despite its biological importance,…”
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Absolute quantification of cellular levels of photosynthesis-related proteins in Synechocystis sp. PCC 6803
Published in Photosynthesis research (01-03-2023)“…Quantifying cellular components is a basic and important step for understanding how a cell works, how it responds to environmental changes, and for…”
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Chromosome-free bacterial cells are safe and programmable platforms for synthetic biology
Published in Proceedings of the National Academy of Sciences - PNAS (24-03-2020)“…A type of chromosome-free cell called SimCells (simple cells) has been generated from Escherichia coli, Pseudomonas putida, and Ralstonia eutropha. The removal…”
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Cryo-EM structure of the Rhodospirillum rubrum RC-LH1 complex at 2.5 Å
Published in Biochemical journal (17-09-2021)“…The reaction centre light-harvesting 1 (RC-LH1) complex is the core functional component of bacterial photosynthesis. We determined the cryo-electron…”
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Adaptation of intracytoplasmic membranes to altered light intensity in Rhodobacter sphaeroides
Published in Biochimica et biophysica acta (01-09-2012)“…The model photosynthetic bacterium Rhodobacter sphaeroides uses a network of bacteriochlorophyll (BChl)–protein complexes embedded in spherical…”
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Zwitterionic Poly(amino acid methacrylate) Brushes
Published in Journal of the American Chemical Society (02-07-2014)“…A new cysteine-based methacrylic monomer (CysMA) was conveniently synthesized via selective thia-Michael addition of a commercially available…”
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Mapping the ultrafast flow of harvested solar energy in living photosynthetic cells
Published in Nature communications (17-10-2017)“…Photosynthesis transfers energy efficiently through a series of antenna complexes to the reaction center where charge separation occurs. Energy transfer in…”
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