Search Results - "Hunt, Steven C"

Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease by Poss, Annelise M, Maschek, J Alan, Cox, James E, Hauner, Benedikt J, Hopkins, Paul N, Hunt, Steven C, Holland, William L, Summers, Scott A, Playdon, Mary C

“…BACKGROUNDCeramides are sphingolipids that play causative roles in diabetes and heart disease, with their serum levels measured clinically as biomarkers of…”
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Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths by Kimura, Masayuki, Stone, Rivka C, Hunt, Steven C, Skurnick, Joan, Lu, Xiaobin, Cao, Xiaojian, Harley, Calvin B, Aviv, Abraham

“…In this protocol we describe a method to obtain telomere length parameters using Southern blots of terminal restriction fragments (TRFs). We use this approach…”
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Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: a Middle Eastern study by Yousri, Noha A, Albagha, Omar M. E, Hunt, Steven C

“…Abstract Background T2D is of high prevalence in the middle east and thus studying its mechanisms is of a significant importance. Using 1026 Qatar BioBank…”
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Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans by MANGINO, Massimo, HWANG, Shih-Jen, WEI CHEN, SRINIVASAN, Sathanur R, KART, Jeremy D, BENETOS, Athanase, EL SHAMIEH, Said, VISVIKIS-SIEST, Sophie, CHRISTENSEN, Kaare, BERENSON, Gerald S, VALDES, Ana M, VINUELA, Ana, SPECTOR, Timothy D, GARCIA, Melissa, ARNETT, Donna K, BROECKEL, Ulrich, PROVINCE, Michael A, PANKOW, James S, KAMMERER, Candace, YONGMEI LIU, NALLS, Michael, TISHKOFF, Sarah, THOMAS, Fridtjof, HUNT, Steven C, ZIV, Elad, PSATY, Bruce M, BIS, Joshua C, ROTTER, Jerome I, TAYLOR, Kent D, SMITH, Erin, SCHORK, Nicholas J, LEVY, Daniel, AVIV, Abraham, KIMURA, Masayuki, FITZPATRICK, Annette L, CHRISTIANSEN, Lene, PETERSEN, Inge, ELBERS, Clara C, HARRIS, Tamara

“…Leukocyte telomere length (LTL) is associated with a number of common age-related diseases and is a heritable trait. Previous genome-wide association studies…”
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Shorter telomere length in Europeans than in Africans due to polygenetic adaptation by Hansen, Matthew E B, Hunt, Steven C, Stone, Rivka C, Horvath, Kent, Herbig, Utz, Ranciaro, Alessia, Hirbo, Jibril, Beggs, William, Reiner, Alexander P, Wilson, James G, Kimura, Masayuki, De Vivo, Immaculata, Chen, Maxine M, Kark, Jeremy D, Levy, Daniel, Nyambo, Thomas, Tishkoff, Sarah A, Aviv, Abraham

“…Leukocyte telomere length (LTL), which reflects telomere length in other somatic tissues, is a complex genetic trait. Eleven SNPs have been shown in…”
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Cancer Incidence and Mortality After Gastric Bypass Surgery by Adams, Ted D., Stroup, Antoinette M., Gress, Richard E., Adams, Kenneth F., Calle, Eugenia E., Smith, Sherman C., Halverson, R. Chad, Simper, Steven C., Hopkins, Paul N., Hunt, Steven C.

“…Despite weight loss recommendations to prevent cancer, cancer outcome studies after intentional weight loss are limited. Recently, reduced cancer mortality…”
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Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study by Hunt, Steven C., Chen, Wei, Gardner, Jeffrey P., Kimura, Masayuki, Srinivasan, Sathanur R., Eckfeldt, John H., Berenson, Gerald S., Aviv, Abraham

“…Summary Leukocyte telomere length (LTL) is ostensibly a bio‐indicator of human aging. Here we report that African Americans have longer LTL than whites. We…”
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Association between the UGT1A128 allele, bilirubin levels, and coronary heart disease in the framingham heart study by LIN, Jing-Ping, O'DONNELL, Christopher J, SCHWAIGER, Johannes P, CUPPLES, L. Adrienne, LINGENHEL, Arno, HUNT, Steven C, SONG YANG, KRONENBERG, Florian

“…Bilirubin is an antioxidant that suppresses lipid oxidation and retards atherosclerosis formation. An inverse association between serum bilirubin and coronary…”
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Six-year changes in health-related quality of life in gastric bypass patients versus obese comparison groups by Kolotkin, Ronette L., Ph.D, Davidson, Lance E., Ph.D, Crosby, Ross D., Ph.D, Hunt, Steven C., Ph.D, Adams, Ted D., Ph.D., M.P.H

“…Abstract Background Few studies have evaluated the long-term outcomes of bariatric surgery patients in relation to obese individuals not participating in…”
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Clinical improvement may not reflect metabolic homeostasis normalization in subjects with and without Roux-En-Y bariatric surgery after 12 years: comparison of surgical subjects to a lean cohort by Butler, Alexandra E, Ramanjaneya, Manjunath, Moin, Abu Saleh Md, Hunt, Steven C, Atkin, Stephen L

“…A 12-year study comparing clinical outcomes following Roux-en-Y bariatric surgery showed long-term weight loss with remission/prevention of type-2-diabetes…”
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Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology by Levy, Daniel, Neuhausen, Susan L, Hunt, Steven C, Kimura, Masayuki, Hwang, Shih-Jen, Chen, Wei, Bis, Joshua C, Fitzpatrick, Annette L, Smith, Erin, Johnson, Andrew D, Gardner, Jeffrey P, Srinivasan, Sathanur R, Schork, Nicholas, Rotter, Jerome I, Herbig, Utz, Psaty, Bruce M, Sastrasinh, Malinee, Murray, Sarah S, Vasan, Ramachandran S, Province, Michael A, Glazer, Nicole L, Lu, Xiaobin, Cao, Xiaojian, Kronmal, Richard, Mangino, Massimo, Soranzo, Nicole, Spector, Tim D, Berenson, Gerald S, Aviv, Abraham

“…Telomeres are engaged in a host of cellular functions, and their length is regulated by multiple genes. Telomere shortening, in the course of somatic cell…”
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Leukocyte Telomere Length and Coronary Artery Calcium by Hunt, Steven C., PhD, Kimura, Masayuki, PhD, Hopkins, Paul N., MD, MSPH, Carr, J. Jeffrey, MD, MSc, Heiss, Gerardo, MD, PhD, Province, Michael A., PhD, Aviv, Abraham, MD

“…Patients with histories of myocardial infarction display shortened leukocyte telomere length (LTL), but conflicting findings have been reported on the relation…”
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Longitudinal Changes in Cardiac Structure and Function in Severe Obesity: 11-Year Follow-Up in the Utah Obesity Study by Litwin, Sheldon E, Adams, Ted D, Davidson, Lance E, McKinlay, Rodrick, Simper, Steven C, Ranson, Lauren, Hunt, Steven C

“…Background Progressive cardiac remodeling and worsening myocardial function over time have been proposed as potential mediators of heart failure in obesity…”
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Cancer and Obesity: Effect of Bariatric Surgery by Adams, Ted D., Hunt, Steven C.

“…Recent international cancer prevention guidelines recommend weight loss, where appropriate, for the purpose of cancer risk reduction. However, limited research…”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Atkin, Stephen L, Ramachandran, Vimal, Yousri, Noha A, Benurwar, Manasi, Simper, Steven C, McKinlay, Rodrick, Adams, Ted D, Najafi-Shoushtari, S Hani, Hunt, Steven C

“…Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. We…”
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Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies by Tang, Hua, Quertermous, Tom, Rodriguez, Beatriz, Kardia, Sharon L.R., Zhu, Xiaofeng, Brown, Andrew, Pankow, James S., Province, Michael A., Hunt, Steven C., Boerwinkle, Eric, Schork, Nicholas J., Risch, Neil J.

“…We have analyzed genetic data for 326 microsatellite markers that were typed uniformly in a large multiethnic population-based sample of individuals as part of…”
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A Genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction by Taylor, Jacquelyn Y., Schwander, Karen, Kardia, Sharon L. R., Arnett, Donna, Liang, Jingjing, Hunt, Steven C., Rao, D.C., Sun, Yan V.

“…Cigarette smoking has been shown to be a health hazard. In addition to being considered a negative lifestyle behavior, studies have shown that cigarette…”
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Association of ideal cardiovascular health and calcified atherosclerotic plaque in the coronary arteries: The National Heart, Lung, and Blood Institute Family Heart Study by Robbins, Jeremy M., MD, Petrone, Andrew B., MPH, Carr, J. Jeffrey, MD, MSc, Pankow, James S., MPH, PhD, Hunt, Steven C., PhD, Heiss, Gerardo, MD, MSc, PhD, Arnett, Donna K., PhD, MSPH, Ellison, R. Curtis, MD, Gaziano, J. Michael, MD, Djoussé, Luc, MD, DSc

“…Background The American Heart Association (AHA) established recommendations based on 7 ideal health behaviors and factors with the goal of improving…”
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Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes by Ramanjaneya, Manjunath, Butler, Alexandra E, Alkasem, Meis, Bashir, Mohammed, Jerobin, Jayakumar, Godwin, Angela, Moin, Abu Saleh Md, Ahmed, Lina, Elrayess, Mohamed A, Hunt, Steven C, Atkin, Stephen L, Abou-Samra, Abdul-Badi

“…Gestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4. Elevated C3…”
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Sugar-Sweetened Beverage Consumption and Calcified Atherosclerotic Plaques in the Coronary Arteries: The NHLBI Family Heart Study by Patel, Yash R., Imran, Tasnim F., Ellison, R. Curtis, Hunt, Steven C., Carr, John Jeffrey, Heiss, Gerardo, Arnett, Donna K., Pankow, James S., Gaziano, J. Michael, Djoussé, Luc

“…Background: Sugar-sweetened beverage (SSB) intake is associated with higher risk of weight gain, diabetes, hypertension, cardiovascular disease, and…”
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