Search Results - "Hunt, Mark J"

A systematic review of the effects of NMDA receptor antagonists on oscillatory activity recorded in vivo by Hunt, Mark J, Kasicki, Stefan

“…Distinct frequency bands can be differentiated from neuronal ensemble recordings, such as local field potentials or electrocorticogram recordings. Recent years…”
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Metastatic breast cancer cells induce altered microglial morphology and electrical excitability in vivo by Simon, Anna, Yang, Ming, Marrison, Joanne L, James, Andrew D, Hunt, Mark J, O'Toole, Peter J, Kaye, Paul M, Whittington, Miles A, Chawla, Sangeeta, Brackenbury, William J

“…An emerging problem in the treatment of breast cancer is the increasing incidence of metastases to the brain. Metastatic brain tumours are incurable and can…”
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Aberrant high frequency oscillations recorded in the rat nucleus accumbens in the methylazoxymethanol acetate neurodevelopmental model of schizophrenia by Goda, Sailaja A., Olszewski, Maciej, Piasecka, Joanna, Rejniak, Karolina, Whittington, Miles A., Kasicki, Stefan, Hunt, Mark J.

“…Altered activity of the nucleus accumbens (NAc) is thought to be a core feature of schizophrenia and animal models of the disease. Abnormal high frequency…”
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Selective Discrimination Learning Impairments in Mice Expressing the Human Huntington's Disease Mutation by Lione, Lisa A, Carter, Rebecca J, Hunt, Mark J, Bates, Gillian P, Morton, A. Jennifer, Dunnett, Stephen B

“…Cognitive decline is apparent in the early stages of Huntington's disease and progressively worsens throughout the course of the disease. Expression of the…”
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Aberrant Network Activity in Schizophrenia by Hunt, Mark J, Kopell, Nancy J, Traub, Roger D, Whittington, Miles A

“…Brain dynamic changes associated with schizophrenia are largely equivocal, with interpretation complicated by many factors, such as the presence of therapeutic…”
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Addressing Pitfalls in Phase-Amplitude Coupling Analysis with an Extended Modulation Index Toolbox by Jurkiewicz, Gabriela J., Hunt, Mark J., Żygierewicz, Jarosław

“…Phase-amplitude coupling (PAC) is proposed to play an essential role in coordinating the processing of information on local and global scales. In recent years,…”
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Effects of NMDA receptor antagonists and antipsychotics on high frequency oscillations recorded in the nucleus accumbens of freely moving mice by Hunt, Mark J., Olszewski, Maciej, Piasecka, Joanna, Whittington, Miles A., Kasicki, Stefan

“…Rationale Abnormal oscillatory activity associated with N -methyl- D -aspartate (NMDA) receptor hypofunction is widely considered to contribute to the symptoms…”
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Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens by Goda, Sailaja A., Piasecka, Joanna, Olszewski, Maciej, Kasicki, Stefan, Hunt, Mark J.

“…Rationale The nucleus accumbens (NAc) is a site critical for the actions of many drugs of abuse. Psychoactive compounds, such as N -methyl- d -aspartate…”
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NMDA receptor antagonist-enhanced high frequency oscillations: Are they generated broadly or regionally specific? by Olszewski, Maciej, Dolowa, Wioleta, Matulewicz, Pawel, Kasicki, Stefan, Hunt, Mark J

“…Abstract Systemic administration of NMDA receptor antagonists, used to model schizophrenia, increase the power of high-frequency oscillations (130–180 Hz, HFO)…”
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Antipsychotic compounds differentially modulate high-frequency oscillations in the rat nucleus accumbens: a comparison of first- and second-generation drugs by Olszewski, Maciej, Piasecka, Joanna, Goda, Sailaja A., Kasicki, Stefan, Hunt, Mark J.

“…Improved understanding of the actions of antipsychotic compounds is critical for a better treatment of schizophrenia. Abnormal oscillatory activity has been…”
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Differential effects produced by ketamine on oscillatory activity recorded in the rat hippocampus, dorsal striatum and nucleus accumbens by Hunt, Mark J, Falinska, Monika, Łęski, Szymon, Wójcik, Daniel K, Kasicki, Stefan

“…Previously, we showed that NMDA antagonists enhance high-frequency oscillations (130–180 Hz) in the nucleus accumbens. However, whether NMDA antagonists can…”
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Hippocampal theta rhythm after serotonergic activation of the pedunculopontine tegmental nucleus in anesthetized rats by Matulewicz, Paweł, Orzeł-Gryglewska, Jolanta, Hunt, Mark J, Trojniar, Weronika, Jurkowlaniec, Edyta

“…Abstract The pedunculopontine tegmental nucleus (PPN), as a part of reticular formation activating system, is thought to be involved in the sleep/wake cycle…”
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Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents by Hunt, Mark J, Morton, A Jennifer

“…The R6/2 transgenic mouse model of Huntington's disease (HD) develops a progressive neurological phenotype that involves severe motor and cognitive…”
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Ketamine Induces Dopamine-Dependent Depression of Evoked Hippocampal Activity in the Nucleus Accumbens in Freely Moving Rats by Hunt, Mark J, Kessal, Karima, Garcia, Rene

“…Noncompetitive NMDA receptor antagonists, such as ketamine, induce a transient schizophrenia-like state in healthy individuals and exacerbate psychosis in…”
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Modulation of high-frequency oscillations associated with NMDA receptor hypofunction in the rodent nucleus accumbens by lamotrigine by Hunt, Mark J., Garcia, Rene, Large, Charles H., Kasicki, Stefan

“…We reported recently that ketamine can increase the power of high-frequency oscillations (HFO) in the rodent nucleus accumbens (NAc), a region implicated in…”
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Local blockade of NMDA receptors in the rat prefrontal cortex increases c-Fos expression in multiple subcortical regions by Nowak, Karolina, Meyza, Ksenia, Nikolaev, Evgeni, Hunt, Mark J, Kasicki, Stefan

“…Ketamine, phencyclidine and MK801 are uncompetitive NMDA receptor (NMDAR) antagonists which are used widely to model certain features of schizophrenia in rats…”
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A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease by Morton, A. Jennifer, Hunt, Mark J., Hodges, Angela K., Lewis, Paul D., Redfern, Amanda J., Dunnett, Stephen B., Jones, Lesley

“…Huntington's disease is a genetic disease caused by a single mutation. It is characterized by progressive movement, emotional and cognitive deficits. R6/2 mice…”
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Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene by Carter, Rebecca J., Hunt, Mark J., Morton, A. Jennifer

“…Mice transgenic for the first exon of the human Huntington's disease (HD) gene carrying an expanded CAG repeat expansion (R6/2 line) develop a progressive…”
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A Conditioned Stressful Environment Causes Short-Term Metaplastic-Like Changes in the Rat Nucleus Accumbens by Hugues, Sandrine, Kessal, Karima, Hunt, Mark J, Garcia, Rene

“…Neurobiologie Comportementale, Equipe Avenir, Institut National de la Santé et de la Recherche Médicale, Université de Nice-Sophia Antipolis, 06108 Nice,…”
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REVERSIBLE INHIBITION OF THE OLFACTORY BULB REDUCES MK801‑ENHACED HIGH‑FREQUENCY OSCILLATIONS (130‑180 HZ) IN THE PIRIFORM CORTEX by Wróbel, Jacek, Średniawa, Władysław, Wójcik, Daniel K, Hunt, Mark J

“…In rodents, NMDAR antagonists enhance high frequency oscillations (HFO) 130-180 Hz measured in LFP in many brain regions. The olfactory bulb (OB), a strong…”
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