Search Results - "Hunt, Donald J."
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1
Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias
Published in The Journal of biological chemistry (18-11-2016)“…Recent three-dimensional structural studies reveal that the central domain of ryanodine receptor (RyR) serves as a transducer that converts long-range…”
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Journal Article -
2
Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release
Published in Biochemical journal (15-05-2008)“…A number of RyR2 (cardiac ryanodine receptor) mutations linked to ventricular arrhythmia and sudden death are located within the last C-terminal approximately…”
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Journal Article -
3
K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association
Published in Biochemical journal (15-06-2007)“…K201 (JTV519), a benzothiazepine derivative, has been shown to possess anti-arrhythmic and cardioprotective properties, but the mechanism of its action is both…”
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Journal Article -
4
Enhanced Store Overload–Induced Ca2+ Release and Channel Sensitivity to Luminal Ca2+ Activation Are Common Defects of RyR2 Mutations Linked to Ventricular Tachycardia and Sudden Death
Published in Circulation research (25-11-2005)“…Ventricular tachycardia (VT) is the leading cause of sudden death, and the cardiac ryanodine receptor (RyR2) is emerging as an important focus in its…”
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Journal Article -
5
Secondary Mathematics Course Trajectories: Understanding Accumulated Disadvantages in Mathematics in Grades 9-12
Published in Journal of school leadership (01-01-2011)“…Schools are institutions in which students' course taking creates series of linked learning opportunities continually shaped by not only curricular structures…”
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Journal Article -
6
K201 (JTV519) suppresses spontaneous Ca super(2+) release and [ super(3)H]ryanodine binding to RyR2 irrespective of FKBP12.6 association
Published in Biochemical journal (01-01-2007)“…K201 (JTV519), a benzothiazepine derivative, has been shown to possess anti-arrhythmic and cardioprotective properties, but the mechanism of its action is both…”
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Journal Article -
7
Enhanced Store Overload–Induced Ca 2+ Release and Channel Sensitivity to Luminal Ca 2+ Activation Are Common Defects of RyR2 Mutations Linked to Ventricular Tachycardia and Sudden Death
Published in Circulation research (25-11-2005)“…Ventricular tachycardia (VT) is the leading cause of sudden death, and the cardiac ryanodine receptor (RyR2) is emerging as an important focus in its…”
Get full text
Journal Article -
8
Enhanced Store Overload-Induced Ca super(2+) Release and Channel Sensitivity to Luminal Ca super(2+) Activation Are Common Defects of RyR2 Mutations Linked to Ventricular Tachycardia and Sudden Death
Published in Circulation research (01-11-2005)“…Ventricular tachycardia (VT) is the leading cause of sudden death, and the cardiac ryanodine receptor (RyR2) is emerging as an important focus in its…”
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Journal Article -
9
Social capital and teacher perceptions of curricular control
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Dissertation -
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Social capital and teacher perceptions of curricular control
Published 01-01-2003“…American public schools will need approximately two million new teachers over the next ten years. Improving perceptions of professional control may increase…”
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Dissertation