Search Results - "Hunt, David W.C."

Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection by Carthy, Christopher M, Yanagawa, Bobby, Luo, Honglin, Granville, David J, Yang, Decheng, Cheung, Paul, Cheung, Caroline, Esfandiarei, Mitra, Rudin, Charles M, Thompson, Craig B, Hunt, David W.C, McManus, Bruce M

“…Coxsackievirus B3, a cytopathic virus in the family Picornaviridae, induces degenerative changes in host cell morphology. Here we demonstrate cytochrome c…”
Get full text

Endothelial Cell Apoptosis: Biochemical Characteristics and Potential Implications for Atherosclerosis by Choy, Jonathan C., Granville, David J., Hunt, David W.C., McManus, Bruce M.

“…The high turnover of endothelial cells (EC) in atherosclerosis suggests that an increase in the frequency of both cell proliferation and cell death is…”
Get full text

Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy by Granville, David J, Carthy, Chris M, Jiang, Huijun, Shore, Gordon C, McManus, Bruce M, Hunt, David W.C

“…Photodynamic therapy (PDT) is a clinical approach that utilizes light-activated drugs for the treatment of a variety of pathologic conditions. The initiating…”
Get full text

Apoptosis associated with esophageal adenocarcinoma: influence of photodynamic therapy by McGarrity, Thomas J, Peiffer, Laurie P, Granville, David J, Carthy, Christopher M, Levy, Julia G, Khandelwal, Mukul, Hunt, David W.C

“…Tumor cell death in vitro by photodynamic therapy (PDT) has been related to the induction of apoptosis. We measured and compared changes in apoptosis and…”
Get full text

DRM02, a novel phosphodiesterase-4 inhibitor with cutaneous anti-inflammatory activity by Hunt, David W.C., Ivanova, Iordanka A., Dagnino, Lina

“…Chronic inflammatory skin disorders are frequently associated with impaired skin barrier function. Selective phosphodiesterase-4 (PDE4) inhibition constitutes…”
Get full text

Consequences of the photodynamic treatment of resting and activated peripheral T lymphocytes by Hunt, David W.C, Jiang, Huijun, Granville, David J, Chan, Agnes H, Leong, Simon, Levy, Julia G

“…The impact of the immunomodulatory photosensitizer benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) and visible light on the survival and…”
Get full text

Inhibition of contact hypersensitivity with different analogs of benzoporphyrin derivative by Simkin, Guillermo O, King, Diane E, Levy, Julia G, Chan, Agnes H, Hunt, David W.C

“…Four structural analogs of benzoporphyrin derivative (BPD), a potent anti-tumor photosensitizer, were evaluated for their capacity to influence the…”
Get full text

Photofrin® increases murine spleen cell transferrin receptor expression and responsiveness to recombinant myeloid and erythroid growth factors by Hunt, David W.C, Jiang, Huijun, Levy, Julia G

“…When given to normal male mice, the photochemotherapeutic agent Photofrin® (porfimer sodium), a complex mixture of monomeric and oligomeric non-metallic…”
Get full text

Apoptosis: molecular aspects of cell death and disease by Granville, D J, Carthy, C M, Hunt, D W, McManus, B M

Get more information

Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization by MATROULE, Jean-Yves, CARTHY, Chris M, GRANVILLE, David J, JOLOIS, Olivier, HUNT, David W. C, PIETTE, Jacques

“…Pyropheophorbide-a methylester (PPME) is a second generation of photosensitizers used in photodynamic therapy (PDT). We demonstrated that PPME…”
Get full text

Ultraviolet B Light Stimulates Interleukin-20 Expression by Human Epithelial Keratinocytes by Hunt, David W. C., Boivin, Wendy A., Fairley, Lindsay A., Jovanovic, Miroslava M., King, Diane E., Salmon, Ruth A., Utting, Oliver B.

“…The proinflammatory cytokine interleukin-20 (IL-20) may exert the majority of its activity in the skin. We examined the effect of various treatments including…”
Get full text

Nuclear factor-κB activation by the photochemotherapeutic agent verteporfin by GRANVILLE, D. J, CARTHY, C. M, JIANG, H, LEVY, J. G, MCMANUS, B. M, MATROULE, J.-Y, PIETTE, J, HUNT, D. W. C

“…Abstract The nuclear factor-kappa B (NF-κB) gene transactivator serves in the formation of immune, inflammatory, and stress responses. In quiescent cells,…”
Get full text

Photodynamic therapy induces caspase-3 activation in HL-60 cells by Granville, D J, Levy, J G, Hunt, D W

“…Caspases have been shown to play a crucial role in apoptosis induced by various deleterious and physiologic stimuli. In this study, we show for the first time…”
Get full text

Selective Action of the Photosensitizer QLT0074 on Activated Human T Lymphocytes by Jiang, Huijun, Granville, David J., North, John R., Richter, Anna M., Hunt, David W. C.

“…ABSTRACT A new photosensitizer, presently designated QLT0074, may have the potential for the treatment of immune and nonimmune conditions with photodynamic…”
Get full text

Influence of interleukin-1α on androgen receptor expression and cytokine secretion by cultured human dermal papilla cells by Boivin, Wendy A., Jiang, Huijun, Utting, Oliver B., Hunt, David W. C.

“…:  Dermal papilla cells (DPC) control the growth character of the hair follicle through their elaboration of mitogenic factors and extracellular matrix…”
Get full text

Studies of human cord blood dendritic cells : evidence for functional immaturity by HUNT, D. W. C, HUPPERTZ, H.-I, HUI-JUH JIANG, PETTY, R. E

“…We have isolated low-density, nonadherent, nonphagocytic, HLA-DR+ve cells with the morphology of dendritic cells (DCs) from the cord blood of full-term newborn…”
Get full text

Neonatal dendritic cells by Petty, Ross E., Hunt, David W.C.

“…The capacity of lymphoid dendritic cells from human cord blood or adult peripheral blood to support a mixed leukocyte reaction in cord blood and adult T cells…”
Get full text

IL-10 Contributes to the Inhibition of Contact Hypersensitivity in Mice Treated with Photodynamic Therapy by Simkin, Guillermo O, Tao, Jing-Song, Levy, Julia G, Hunt, David W. C

“…We have explored the effect of photodynamic therapy (PDT) with verteporfin on the induction and expression of contact hypersensitivity (CHS) to…”
Get full text

Overexpression of Bcl-X L prevents caspase-3-mediated activation of DNA fragmentation factor (DFF) produced by treatment with the photochemotherapeutic agent BPD-MA by Granville, David J, Jiang, Huijun, An, Mary T, Levy, Julia G, McManus, Bruce M, Hunt, David W.C

“…Photodynamic therapy (PDT) is a clinically effective cancer treatment. For human promyelocytic leukemia HL-60 cells, cleavage of pro-caspase-3…”
Get full text

Overexpression of Bcl-X(L) prevents caspase-3-mediated activation of DNA fragmentation factor (DFF) produced by treatment with the photochemotherapeutic agent BPD-MA by Granville, D J, Jiang, H, An, M T, Levy, J G, McManus, B M, Hunt, D W

“…Photodynamic therapy (PDT) is a clinically effective cancer treatment. For human promyelocytic leukemia HL-60 cells, cleavage of pro-caspase-3…”
Get full text