Search Results - "Hunt, David M."
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Avian Visual Pigments: Characteristics, Spectral Tuning, and Evolution
Published in The American naturalist (01-01-2007)“…Birds are highly visual animals with complex visual systems. In this article, we discuss the spectral characteristics and genetic mechanisms of the spectral…”
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Molecular ecology and adaptation of visual photopigments in craniates
Published in Molecular ecology (01-07-2012)“…In craniates, opsin‐based photopigments expressed in the eye encode molecular ‘light sensors’ that constitute the initial protein in photoreception and the…”
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3
The origins of the full-field flash electroretinogram b-wave
Published in Frontiers in molecular neuroscience (03-07-2023)“…The electroretinogram (ERG) measures the electrical activity of retinal neurons and glial cells in response to a light stimulus. Amongst other techniques,…”
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4
Evolution and spectral tuning of visual pigments in birds and mammals
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (12-10-2009)“…Variation in the types and spectral characteristics of visual pigments is a common mechanism for the adaptation of the vertebrate visual system to prevailing…”
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Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K + Channel Subunits Kv8.2 and K2.1
Published in International journal of molecular sciences (05-05-2021)“…Cone Dystrophy with Supernormal Rod Response (CDSRR) is a rare autosomal recessive disorder leading to severe visual impairment in humans, but little is known…”
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Visual Pigments, Ocular Filters and the Evolution of Snake Vision
Published in Molecular biology and evolution (01-10-2016)“…Much of what is known about the molecular evolution of vertebrate vision comes from studies of mammals, birds and fish. Reptiles (especially snakes) have…”
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Visual Opsin Diversity in Sharks and Rays
Published in Molecular biology and evolution (01-03-2020)“…The diversity of color vision systems found in extant vertebrates suggests that different evolutionary selection pressures have driven specializations in…”
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Evolution of Vertebrate Phototransduction: Cascade Activation
Published in Molecular biology and evolution (01-08-2016)“…We applied high-throughput sequencing to eye tissue from several species of basal vertebrates (a hagfish, two species of lamprey, and five species of…”
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Evolution of the calcium feedback steps of vertebrate phototransduction
Published in Open biology (26-09-2018)“…We examined the genes encoding the proteins that mediate the Ca-feedback regulatory system in vertebrate rod and cone phototransduction. These proteins…”
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Visual opsin expression and morphological characterization of retinal photoreceptors in the pouched lamprey (Geotria australis, Gray)
Published in Journal of comparative neurology (1911) (01-06-2021)“…Lampreys are extant members of the agnathan (jawless) vertebrates that diverged ~500 million years ago, during a critical stage of vertebrate evolution when…”
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The evolution of early vertebrate photoreceptors
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (12-10-2009)“…to be used by all subsequent vertebrate descendents. Image-forming eyes were under tremendous selection pressure and the ability to identify suitable prey and…”
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Guanylate cyclases and associated activator proteins in retinal disease
Published in Molecular and cellular biochemistry (01-01-2010)“…Two isoforms of guanylate cyclase, GC1 and GC2 encoded by GUCY2D and GUCY2F, are responsible for the replenishment of cGMP in photoreceptors after exposure to…”
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Spectral tuning and evolution of primate short-wavelength-sensitive visual pigments
Published in Proceedings of the Royal Society. B, Biological sciences (22-01-2012)“…The peak sensitivities (λmax) of the short-wavelength-sensitive-1 (SWS1) pigments in mammals range from the ultraviolet (UV) (360–400 nm) to the violet…”
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The effect of cone opsin mutations on retinal structure and the integrity of the photoreceptor mosaic
Published in Investigative ophthalmology & visual science (05-12-2012)“…To evaluate retinal structure and photoreceptor mosaic integrity in subjects with OPN1LW and OPN1MW mutations. Eleven subjects were recruited, eight of whom…”
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Evolution of the cichlid visual palette through ontogenetic subfunctionalization of the opsin gene arrays
Published in Molecular biology and evolution (01-08-2006)“…The evolution of cone opsin genes is characterized by a dynamic process of gene birth and death through gene duplication and loss. However, the forces…”
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Mix and Match Color Vision: Tuning Spectral Sensitivity by Differential Opsin Gene Expression in Lake Malawi Cichlids
Published in Current biology (11-10-2005)“…Cichlid fish of the East African Rift Lakes are renowned for their diversity and offer a unique opportunity to study adaptive changes in the visual system in…”
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Differential stability of variant OPN1LW gene transcripts in myopic patients
Published in Molecular vision (2019)“…In Bornholm eye disease, a defect in the splicing of transcripts from a variant opsin gene leads to a depletion in spliced transcript levels and, consequently,…”
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The influence of ontogeny and light environment on the expression of visual pigment opsins in the retina of the black bream, Acanthopagrus butcheri
Published in Journal of experimental biology (01-05-2008)“…The correlation between ontogenetic changes in the spectral absorption characteristics of retinal photoreceptors and expression of visual pigment opsins was…”
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Evolution of the shut-off steps of vertebrate phototransduction
Published in Open biology (01-01-2018)“…Different isoforms of the genes involved in phototransduction are expressed in vertebrate rod and cone photoreceptors, providing a unique example of parallel…”
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Retinal amino acid neurochemistry of the southern hemisphere lamprey, Geotria australis
Published in PloS one (13-03-2013)“…Lampreys are one of the two surviving groups of the agnathan (jawless) stages in vertebrate evolution and are thus ideal candidates for elucidating the…”
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