Search Results - "Hunjan, Suchete"

DDI2 Is a Ubiquitin-Directed Endoprotease Responsible for Cleavage of Transcription Factor NRF1 by Dirac-Svejstrup, A. Barbara, Walker, Jane, Faull, Peter, Encheva, Vesela, Akimov, Vyacheslav, Puglia, Michele, Perkins, David, Kümper, Sandra, Hunjan, Suchete S., Blagoev, Blagoy, Snijders, Ambrosius P., Powell, David J., Svejstrup, Jesper Q.

“…The Ddi1/DDI2 proteins are ubiquitin shuttling factors, implicated in a variety of cellular functions. In addition to ubiquitin-binding and ubiquitin-like…”
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Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products by O’Brien Gore, Charlotte, Billman, Amy, Hunjan, Suchete, Colebrook, Jayne, Choy, Desmond, Li, Wilson, Haynes, Jack, Wade, Jennifer, Hobern, Emily, McDonald, Louisa, Papa, Sophie, Brugman, Martijn, Kordasti, Shahram, Montiel-Equihua, Claudia

“…The antitumor activity of adoptive T cell therapies (ACT) is highly dependent on the expansion, persistence, and continued activity of adoptively transferred…”
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Kinase array design, back to front: Biaryl amides by Baldwin, Ian, Bamborough, Paul, Haslam, Claudine G., Hunjan, Suchete S., Longstaff, Tim, Mooney, Christopher J., Patel, Shila, Quinn, Jo, Somers, Don O.

“…Most kinase-directed array strategies aim to add functionality to a fragment that binds in the purine subpocket of the ATP-site. Here, an alternative…”
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The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist by Rimland, Joseph, Dunne, Angela, Hunjan, Suchete S., Sasse, Rosemary, Uings, Iain, Montanari, Dino, Caivano, Matilde, Shah, Poonam, Standing, David, Gray, David, Brown, David, Cairns, William, Trump, Ryan, Smith, Paul W., Bertheleme, Nicolas, D’Alessandro, Pier, Gul, Sheraz, Vimal, Mythily, Smith, David N., Watson, Stephen P.

“…The identification of novel, potent, non-steroidal/small molecule functional GR antagonist GSK1564023A PR is described. Associated structure–activity…”
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