Search Results - "Hung Lo, Kim"
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The Safety and Efficacy of Infliximab in Moderate to Severe Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-05-2007)“…Chronic obstructive pulmonary disease (COPD) is a progressive, smoking-related, inflammatory lung disease in which tumor necrosis factor-alpha is overexpressed…”
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Evaluation of Improvement in Skin and Nail Psoriasis in Bio‐naïve Patients With Active Psoriatic Arthritis Treated With Golimumab: Results Through Week 52 of the GO‐VIBRANT Study
Published in ACR open rheumatology (01-11-2020)“…Objective To evaluate whether intravenous (IV) golimumab produces improvements in skin and nail symptoms that are concomitant with improvements in quality of…”
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Validating the Simplified Endoscopic Mucosal Assessment for Crohn’s Disease: A Novel Method for Assessing Disease Activity
Published in Inflammatory bowel diseases (05-07-2023)“…Abstract Background To demonstrate treatment efficacy in Crohn’s disease (CD), regulatory authorities require that trials include an endoscopic…”
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A Randomized, Double-blind, Placebo-controlled Study of Tumor Necrosis Factor-α Blockade in Severe Persistent Asthma
Published in American journal of respiratory and critical care medicine (01-04-2009)“…The treatment effect of golimumab, a human monoclonal antibody against tumor necrosis factor (TNF)-alpha, in severe persistent asthma is unknown. To assess the…”
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Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe Heart failure: Results of the anti-TNF therapy against congestive Heart failure (ATTACH) trial
Published in Circulation (New York, N.Y.) (01-07-2003)“…Preclinical and preliminary clinical data have suggested that tumor necrosis factor-alpha (TNFalpha) may play a role in the evolution and progression of heart…”
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Infliximab Therapy in Patients with Chronic Sarcoidosis and Pulmonary Involvement
Published in American journal of respiratory and critical care medicine (01-10-2006)“…Evidence suggests that tumor necrosis factor (TNF)-alpha plays an important role in the pathophysiology of sarcoidosis. To assess the efficacy of infliximab in…”
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Outcomes in Adult Inflammatory Bowel Disease Clinical Trials: Assessment of Similarity Among Participants with Adolescent-onset and Adult-onset Disease
Published in Journal of Crohn's and colitis (14-08-2024)“…Abstract Background and Aims Most paediatric inflammatory bowel disease [IBD] studies are performed after medications are approved in adults, and the majority…”
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Inhibition of radiographic progression across levels of composite index-defined disease activity in patients with active psoriatic arthritis treated with intravenous golimumab: results from a phase-3, double-blind, placebo-controlled trial
Published in Arthritis research & therapy (06-03-2020)“…In the GO-VIBRANT trial of intravenous golimumab in psoriatic arthritis (PsA), golimumab significantly inhibited radiographic progression. In post hoc…”
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Changes in chest roentgenogram of sarcoidosis patients during a clinical trial of infliximab therapy: comparison of different methods of evaluation
Published in Chest (01-08-2009)“…The best method to interpret the chest roentgenogram and its sensitivity to detect effect of treatment for sarcoidosis remains unclear. In a double-blind,…”
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304 Dysregulated serum cytokines in association with clinical manifestations in patients with systemic lupus erythematosus
Published in Lupus science & medicine (16-05-2024)“…BackgroundSystemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease affecting multiple organ systems, making clinical trial design challenging…”
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Effect of Intravenous Golimumab on Fatigue and the Relationship with Clinical Response in Adults with Active Ankylosing Spondylitis in the Phase 3 GO-ALIVE Study
Published in Rheumatology and therapy. (01-08-2023)“…Introduction We studied the effect of intravenous (IV)-golimumab on fatigue and the association of fatigue improvement with clinical response post hoc in…”
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The Effect of Intravenous Golimumab on Health-related Quality of Life in Rheumatoid Arthritis: 24-week Results of the Phase III GO-FURTHER Trial
Published in Journal of rheumatology (01-06-2014)“…To evaluate the effects of intravenous (IV) golimumab 2 mg/kg + methotrexate (MTX) on patient-reported measures of health-related quality of life (HRQOL) in…”
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Inflammatory Profile and Response to Anti-Tumor Necrosis Factor Therapy in Patients with Chronic Pulmonary Sarcoidosis
Published in Clinical and Vaccine Immunology (01-06-2011)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Maintenance of Efficacy and Safety of Ustekinumab Through One Year in a Phase II Multicenter, Prospective, Randomized, Double‐Blind, Placebo‐Controlled Crossover Trial of Patients With Active Systemic Lupus Erythematosus
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-05-2020)“…Objective To evaluate the efficacy and safety of ustekinumab through 1 year in a phase II trial in patients with systemic lupus erythematosus (SLE). Methods…”
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Safety and Efficacy of Intravenous Golimumab in Patients With Active Psoriatic Arthritis: Results Through Week Twenty-Four of the GO-VIBRANT Study
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2017)“…To evaluate the safety and efficacy of intravenous (IV) golimumab treatment in psoriatic arthritis (PsA). In this phase III, randomized, double-blind,…”
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Safety and Efficacy of Golimumab Administered Intravenously in Adults with Ankylosing Spondylitis: Results through Week 28 of the GO-ALIVE Study
Published in Journal of rheumatology (01-03-2018)“…To evaluate the safety and efficacy of intravenous golimumab (GOL) in patients with active ankylosing spondylitis (AS). In a phase III, randomized,…”
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Efficacy and Safety of Ustekinumab in Patients With Active Systemic Lupus Erythematosus: Results of a Phase II Open-label Extension Study
Published in Journal of rheumatology (01-04-2022)“…To evaluate the long-term efficacy and safety of ustekinumab through 2 years in patients with active systemic lupus erythematosus (SLE). This was a…”
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Safety and Efficacy of Intravenous Golimumab in Adults with Ankylosing Spondylitis: Results through 1 Year of the GO-ALIVE Study
Published in Journal of rheumatology (01-10-2019)“…Evaluate safety and efficacy of intravenous (IV) golimumab (GOL) in patients with active ankylosing spondylitis (AS) through 1 year. A total of 208 patients…”
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