Search Results - "Hung, Sandy SC"
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A single‐cell transcriptome atlas of the adult human retina
Published in The EMBO journal (16-09-2019)“…The retina is a specialized neural tissue that senses light and initiates image processing. Although the functional organization of specific retina cells has…”
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Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina
Published in Human gene therapy (01-11-2019)“…Safe delivery of CRISPR/Cas endonucleases remains one of the major barriers to the widespread application of genome editing. We previously reported the utility…”
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Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells
Published in Stem Cells International (01-01-2016)“…Background. Human induced pluripotent stem cells (iPSCs) are an attractive source of cardiomyocytes for cardiac repair and regeneration. In this study, we aim…”
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A Simple Cloning-free Method to Efficiently Induce Gene Expression Using CRISPR/Cas9
Published in Molecular therapy. Nucleic acids (01-03-2019)“…Gain-of-function studies often require the tedious cloning of transgene cDNA into vectors for overexpression beyond the physiological expression levels. The…”
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Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells
Published in DNA research (01-08-2013)“…Mouse embryonic stem (ES) cells are prototypical stem cells that remain undifferentiated in culture for long periods, yet maintain the ability to differentiate…”
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