Search Results - "Hung, Rayjean"

Biomarker-Based Lung Cancer Screening Eligibility: Implementation Considerations by Hung, Rayjean J

“…With the convergence of promising biomarkers for lung cancer risk stratifications, and the increasing need for better eligibility assessment for lung cancer…”
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Previous lung diseases and lung cancer risk: a systematic review and meta-analysis by Brenner, Darren R, McLaughlin, John R, Hung, Rayjean J

“…In order to review the epidemiologic evidence concerning previous lung diseases as risk factors for lung cancer, a meta-analysis and systematic review was…”
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Sensitive tumour detection and classification using plasma cell-free DNA methylomes by Shen, Shu Yi, Singhania, Rajat, Fehringer, Gordon, Chakravarthy, Ankur, Roehrl, Michael H. A., Chadwick, Dianne, Zuzarte, Philip C., Borgida, Ayelet, Wang, Ting Ting, Li, Tiantian, Kis, Olena, Zhao, Zhen, Spreafico, Anna, Medina, Tiago da Silva, Wang, Yadon, Roulois, David, Ettayebi, Ilias, Chen, Zhuo, Chow, Signy, Murphy, Tracy, Arruda, Andrea, O’Kane, Grainne M., Liu, Jessica, Mansour, Mark, McPherson, John D., O’Brien, Catherine, Leighl, Natasha, Bedard, Philippe L., Fleshner, Neil, Liu, Geoffrey, Minden, Mark D., Gallinger, Steven, Goldenberg, Anna, Pugh, Trevor J., Hoffman, Michael M., Bratman, Scott V., Hung, Rayjean J., De Carvalho, Daniel D.

“…The use of liquid biopsies for cancer detection and management is rapidly gaining prominence 1 . Current methods for the detection of circulating tumour DNA…”
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A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer by Gormley, Mark, Dudding, Tom, Sanderson, Eleanor, Martin, Richard M., Thomas, Steven, Tyrrell, Jessica, Ness, Andrew R., Brennan, Paul, Munafò, Marcus, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F., Diergaarde, Brenda, Hung, Rayjean J., Liu, Geoffrey, Davey Smith, George, Richmond, Rebecca C.

“…The independent effects of smoking and alcohol in head and neck cancer are not clear, given the strong association between these risk factors. Their apparent…”
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Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium by Shepshelovich, Daniel, Xu, Wei, Lu, Lin, Fares, Aline, Yang, Ping, Christiani, David, Zhang, Jie, Shiraishi, Kouya, Ryan, Brid M, Chen, Chu, Schwartz, Ann G, Tardon, Adonina, Wu, Xifeng, Schabath, Matthew B, Teare, M Dawn, Le Marchand, Loic, Zhang, Zuo-Feng, Field, John K, Brenner, Hermann, Diao, Nancy, Xie, Juntao, Kohno, Takashi, Harris, Curtis C, Wenzlaff, Angela S, Fernandez-Tardon, Guillermo, Ye, Yuanqing, Taylor, Fiona, Wilkens, Lynne R, Davies, Michael, Liu, Yi, Barnett, Matt J, Goodman, Gary E, Morgenstern, Hal, Holleczek, Bernd, Brown, M Catherine, Liu, Geoffrey, Hung, Rayjean J

“…The relationships between morbid obesity, changes in body mass index (BMI) before cancer diagnosis, and lung cancer outcomes by histology (SCLC and NSCLC) have…”
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Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations by Dai, Juncheng, Lv, Jun, Zhu, Meng, Wang, Yuzhuo, Qin, Na, Ma, Hongxia, He, Yong-Qiao, Zhang, Ruoxin, Tan, Wen, Fan, Jingyi, Wang, Tianpei, Zheng, Hong, Sun, Qi, Wang, Lijuan, Huang, Mingtao, Ge, Zijun, Yu, Canqing, Guo, Yu, Wang, Tong-Min, Wang, Jie, Xu, Lin, Wu, Weibing, Chen, Liang, Bian, Zheng, Walters, Robin, Millwood, Iona Y, Li, Xi-Zhao, Wang, Xin, Hung, Rayjean J, Christiani, David C, Chen, Haiquan, Wang, Mengyun, Wang, Cheng, Jiang, Yue, Chen, Kexin, Chen, Zhengming, Jin, Guangfu, Wu, Tangchun, Lin, Dongxin, Hu, Zhibin, Amos, Christopher I, Wu, Chen, Wei, Qingyi, Jia, Wei-Hua, Li, Liming, Shen, Hongbing

“…Genetic variation has an important role in the development of non-small-cell lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully…”
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Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium by Zhang, Li Rita, Morgenstern, Hal, Greenland, Sander, Chang, Shen‐Chih, Lazarus, Philip, Teare, M. Dawn, Woll, Penella J., Orlow, Irene, Cox, Brian, Brhane, Yonathan, Liu, Geoffrey, Hung, Rayjean J.

“…To investigate the association between cannabis smoking and lung cancer risk, data on 2,159 lung cancer cases and 2,985 controls were pooled from 6…”
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A review of the application of inflammatory biomarkers in epidemiologic cancer research by Brenner, Darren R, Scherer, Dominique, Muir, Kenneth, Schildkraut, Joellen, Boffetta, Paolo, Spitz, Margaret R, Le Marchand, Loic, Chan, Andrew T, Goode, Ellen L, Ulrich, Cornelia M, Hung, Rayjean J

“…Inflammation is a facilitating process for multiple cancer types. It is believed to affect cancer development and progression through several etiologic…”
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Lung Cancer Absolute Risk Models for Mortality in an Asian Population using the China Kadoorie Biobank by Warkentin, Matthew T, Tammemägi, Martin C, Espin-Garcia, Osvaldo, Budhathoki, Sanjeev, Liu, Geoffrey, Hung, Rayjean J

“…Lung cancer is the leading cause of cancer mortality globally. Early detection through risk-based screening can markedly improve prognosis. However, most risk…”
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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study by Gormley, Mark, Yarmolinsky, James, Dudding, Tom, Burrows, Kimberley, Martin, Richard M, Thomas, Steven, Tyrrell, Jessica, Brennan, Paul, Pring, Miranda, Boccia, Stefania, Olshan, Andrew F, Diergaarde, Brenda, Hung, Rayjean J, Liu, Geoffrey, Legge, Danny, Tajara, Eloiza H, Severino, Patricia, Lacko, Martin, Ness, Andrew R, Davey Smith, George, Vincent, Emma E, Richmond, Rebecca C

“…Head and neck squamous cell carcinoma (HNSCC), which includes cancers of the oral cavity and oropharynx, is a cause of substantial global morbidity and…”
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USPSTF2013 versus PLCOm2012 lung cancer screening eligibility criteria (International Lung Screening Trial): interim analysis of a prospective cohort study by Tammemägi, Martin C, Ruparel, Mamta, Tremblay, Alain, Myers, Renelle, Mayo, John, Yee, John, Atkar-Khattra, Sukhinder, Yuan, Ren, Cressman, Sonya, English, John, Bedard, Eric, MacEachern, Paul, Burrowes, Paul, Quaife, Samantha L, Marshall, Henry, Yang, Ian, Bowman, Rayleen, Passmore, Linda, McWilliams, Annette, Brims, Fraser, Lim, Kuan Pin, Mo, Lin, Melsom, Stephen, Saffar, Bann, Teh, Mark, Sheehan, Ramon, Kuok, Yijin, Manser, Renee, Irving, Louis, Steinfort, Daniel, McCusker, Mark, Pascoe, Diane, Fogarty, Paul, Stone, Emily, Lam, David C L, Ng, Ming-Yen, Vardhanabhuti, Varut, Berg, Christine D, Hung, Rayjean J, Janes, Samuel M, Fong, Kwun, Lam, Stephen

“…Lung cancer is a major health problem. CT lung screening can reduce lung cancer mortality through early diagnosis by at least 20%. Screening high-risk…”
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Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization by Zhou, Wen, Liu, Geoffrey, Hung, Rayjean J., Haycock, Philip C., Aldrich, Melinda C., Andrew, Angeline S., Arnold, Susanne M., Bickeböller, Heike, Bojesen, Stig E., Brennan, Paul, Brunnström, Hans, Melander, Olle, Caporaso, Neil E., Landi, Maria Teresa, Chen, Chu, Goodman, Gary E., Christiani, David C., Cox, Angela, Field, John K., Johansson, Mikael, Kiemeney, Lambertus A., Lam, Stephen, Lazarus, Philip, Le Marchand, Loïc, Rennert, Gad, Risch, Angela, Schabath, Matthew B., Shete, Sanjay S., Tardón, Adonina, Zienolddiny, Shanbeh, Shen, Hongbing, Amos, Christopher I.

“…At the time of cancer diagnosis, body mass index (BMI) is inversely correlated with lung cancer risk, which may reflect reverse causality and confounding due…”
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Genetic Polymorphisms in the Base Excision Repair Pathway and Cancer Risk: A HuGE Review by Hung, Rayjean J., Hall, Janet, Brennan, Paul, Boffetta, Paolo

“…Genetic variations in DNA repair genes are thought to modulate DNA repair capacity and are suggested to be related to cancer risk. However, epidemiologic…”
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Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors by VAISSIERE, Thomas, HUNG, Rayjean J, TOST, Jörg, BOFFETTA, Paolo, HERCEG, Zdenko, ZARIDZE, David, MOUKERIA, Anush, CUENIN, Cyrille, FASOLO, Virginie, FERRO, Gilles, PALIWAL, Anupam, HAINAUT, Pierre, BRENNAN, Paul

“…The global increase in lung cancer burden, together with its poor survival and resistance to classical chemotherapy, underscores the need for identification of…”
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Systematic Review of Genetic Variation in Chromosome 5p15.33 and Telomere Length as Predictive and Prognostic Biomarkers for Lung Cancer by Kachuri, Linda, Latifovic, Lidija, Liu, Geoffrey, Hung, Rayjean J

“…Lung cancer remains the leading cause of cancer mortality worldwide. Known histomolecular characteristics and genomic profiles provide limited insight into…”
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Nicotine dependence as a risk factor for upper aerodigestive tract (UADT) cancers: A mediation analysis by Thomas, Sera, Carroll, June C, Brown, M Catherine, Chen, Zhou, Mirshams, Maryam, Patel, Devalben, Boyd, Kevin, Pierre, Andrew, Goldstein, David P, Giuliani, Meredith E, Xu, Wei, Eng, Lawson, Khodayari Moez, Elham, Liu, Geoffrey, Hung, Rayjean J

“…This study investigated nicotine dependence as an independent risk factor for upper aerodigestive tract (UADT) cancers, including lung and head and neck…”
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Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors by Hong, Wei, Li, Ang, Liu, Yanhong, Xiao, Xiangjun, Christiani, David C, Hung, Rayjean J, McKay, James, Field, John, Amos, Christopher I, Cheng, Chao

“…Clonal hematopoiesis (CH) is a phenomenon caused by expansion of white blood cells descended from a single hematopoietic stem cell. While CH can be associated…”
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Canadian COVID-19 host genetics cohort replicates known severity associations by Garg, Elika, Arguello-Pascualli, Paola, Vishnyakova, Olga, Halevy, Anat R, Yoo, Samantha, Brooks, Jennifer D, Bull, Shelley B, Gagnon, France, Greenwood, Celia M T, Hung, Rayjean J, Lawless, Jerald F, Lerner-Ellis, Jordan, Dennis, Jessica K, Abraham, Rohan J S, Garant, Jean-Michel, Thiruvahindrapuram, Bhooma, Jones, Steven J M, Strug, Lisa J, Paterson, Andrew D, Sun, Lei, Elliott, Lloyd T

“…The HostSeq initiative recruited 10,059 Canadians infected with SARS-CoV-2 between March 2020 and March 2023, obtained clinical information on their disease…”
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Multiple imputation and clinico‐serological models to predict human papillomavirus status in oropharyngeal carcinoma: An alternative when tissue is unavailable by Ren, Jianjun, Xu, Wei, Su, Jie, Ren, Xue, Cheng, Dangxiao, Chen, Zhuo, Bender, Noemi, Mirshams, Maryam, Habbous, Steven, Almeida, John R., Perez‐Ordonez, Bayardo, Goldstein, David P, Wang, Jennifer R, Bratman, Scott V., Huang, Shao Hui, Jang, Raymond, Zhao, Yu, Waterboer, Tim, Hung, Rayjean J., Liu, Geoffrey

“…In cancer epidemiological studies, determination of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) typically depends on the…”
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Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model by Hung, Rayjean J, Warkentin, Matthew T, Brhane, Yonathan, Chatterjee, Nilanjan, Christiani, David C, Landi, Maria Teresa, Caporaso, Neil E, Liu, Geoffrey, Johansson, Mattias, Albanes, Demetrius, Marchand, Loic Le, Tardon, Adonina, Rennert, Gad, Bojesen, Stig E, Chen, Chu, Field, John K, Kiemeney, Lambertus A, Lazarus, Philip, Zienolddiny, Shanbeth, Lam, Stephen, Andrew, Angeline S, Arnold, Susanne M, Aldrich, Melinda C, Bickeböller, Heike, Risch, Angela, Schabath, Matthew B, McKay, James D, Brennan, Paul, Amos, Christopher I

“…Lung cancer is the leading cause of cancer-related death globally. An improved risk stratification strategy can increase efficiency of low-dose CT (LDCT)…”
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