Search Results - "Hung, Paul J."
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Nanoliter scale microbioreactor array for quantitative cell biology
Published in Biotechnology and bioengineering (05-05-2006)“…A nanoliter scale microbioreactor array was designed for multiplexed quantitative cell biology. An addressable 8 × 8 array of three nanoliter chambers was…”
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Journal Article -
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A novel high aspect ratio microfluidic design to provide a stable and uniform microenvironment for cell growth in a high throughput mammalian cell culture array
Published in Lab on a chip (01-01-2005)“…We present a high aspect ratio microfluidic device for culturing cells inside an array of microchambers with continuous perfusion of medium. The device was…”
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3
A microfluidic system for dynamic yeast cell imaging
Published in BioTechniques (01-01-2008)“…The investigation of cellular processes and gene regulatory networks within living cells requires the development of improved technology for dynamic, single…”
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4
An artificial liver sinusoid with a microfluidic endothelial-like barrier for primary hepatocyte culture
Published in Biotechnology and bioengineering (01-08-2007)“…Primary hepatocytes represent a physiologically relevant model for drug toxicity screening. Here, we created a biologically inspired artificial liver sinusoid…”
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Continuous perfusion microfluidic cell culture array for high-throughput cell-based assays
Published in Biotechnology and bioengineering (05-01-2005)“…We present for the first time a microfluidic cell culture array for long‐term cellular monitoring. The 10 × 10 array could potentially assay 100 different…”
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Microfluidic array for three-dimensional perfusion culture of human mammary epithelial cells
Published in Biomedical microdevices (01-08-2011)“…The ability to culture cells in three dimensional extracellular matrix (3D ECM) has proven to be an important tool for laboratory biology. Here, we demonstrate…”
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Automated live cell imaging of cell migration across a microfluidic-controlled chemoattractant gradient
Published in Nature methods (01-11-2015)“…The quantification of cell-migration behavior in response to gradients is critical for understanding cellular movement and development. The CellASIC ® ONIX…”
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Open-access microfluidic patch-clamp array with raised lateral cell trapping sites
Published in Lab on a chip (01-12-2006)“…A novel open-access microfluidic patch-clamp array chip with lateral cell trapping sites raised above the bottom plane of the chip was developed by combining…”
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Dynamic cell culture: a microfluidic function generator for live cell microscopy
Published in Lab on a chip (07-01-2009)“…We present a microfluidic system for time-lapsed, live cell microscopy with the ability to control solution exchange via a dynamic flow controller. The…”
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Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs
Published in Applied physics letters (30-05-2005)“…Direct cell-cell communication between adjacent cells is vital for the development and regulation of functional tissues. However, current biological techniques…”
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Microfluidic environment for high density hepatocyte culture
Published in Biomedical microdevices (01-02-2008)“…We present a microfluidic bioreactor for culturing high-density arrays of hepatocytes in a tissue-like micro-architecture. The microfluidic environment…”
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Microfabricated suspensions for electrical connections on the tunable elastomer membrane
Published in Applied physics letters (13-12-2004)“…Electrical connections through microfabricated suspensions on a pneumatically pumped elastomer membrane were demonstrated. A method to fabricate the…”
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Journal Article -
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Microfluidic System for Automated Cell-Based Assays
Published in Journal of Laboratory Automation (01-12-2007)“…Microfluidic cell culture is a promising technology for applications in the drug screening industry. Key benefits include improved biological function,…”
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Microfluidic Tissue Model for Live Cell Screening
Published in Biotechnology progress (01-07-2007)“…We have developed a microfluidic platform modeled after the physiologic microcirculation for multiplexed tissue‐like culture and high‐throughput analysis. Each…”
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Microfluidic tissue model for live cell screening
Published in Biotechnology progress (01-07-2007)“…We have developed a microfluidic platform modeled after the physiologic microcirculation for multiplexed tissue-like culture and high-throughput analysis. Each…”
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Continuous and agile beam steerable diode lasers
Published in Summaries of Papers Presented at the Lasers and Electro-Optics. CLEO '02. Technical Diges (2002)“…Summary from only given. This paper demonstrates the first monolithically fabricated laser beam steering device based on GaAs-based MEMS. Since the laser and…”
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Conference Proceeding -
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Microfluidic Method for Primary Neuron Culture and Analysis
Published in R & D : reading for the R & D community (07-01-2015)“…Dissecting neuron function, while crucially important for understanding normal and pathological neurological processes, requires measuring the responses of…”
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