Search Results - "Hung, Adriana M"

Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals by Stanzick, Kira J., Li, Yong, Schlosser, Pascal, Gorski, Mathias, Wuttke, Matthias, Thomas, Laurent F., Rasheed, Humaira, Rowan, Bryce X., Graham, Sarah E., Vanderweff, Brett R., Patil, Snehal B., Robinson-Cohen, Cassiane, Gaziano, John M., O’Donnell, Christopher J., Willer, Cristen J., Hallan, Stein, Åsvold, Bjørn Olav, Gessner, Andre, Hung, Adriana M., Pattaro, Cristian, Köttgen, Anna, Stark, Klaus J., Heid, Iris M., Winkler, Thomas W.

“…Genes underneath signals from genome-wide association studies (GWAS) for kidney function are promising targets for functional studies, but prioritizing…”
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Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments by Sheng, Xin, Guan, Yuting, Ma, Ziyuan, Wu, Junnan, Liu, Hongbo, Qiu, Chengxiang, Vitale, Steven, Miao, Zhen, Seasock, Matthew J., Palmer, Matthew, Shin, Myung K., Duffin, Kevin L., Pullen, Steven S., Edwards, Todd L., Hellwege, Jacklyn N., Hung, Adriana M., Li, Mingyao, Voight, Benjamin F., Coffman, Thomas M., Brown, Christopher D., Susztak, Katalin

“…The functional interpretation of genome-wide association studies (GWAS) is challenging due to the cell-type-dependent influences of genetic variants. Here, we…”
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IL-1 Inhibition and Vascular Function in CKD by Nowak, Kristen L, Chonchol, Michel, Ikizler, Talat Alp, Farmer-Bailey, Heather, Salas, Natjalie, Chaudhry, Rafia, Wang, Wei, Smits, Gerard, Tengesdal, Isak, Dinarello, Charles A, Hung, Adriana M

“…Vascular endothelial dysfunction and increased arterial stiffness contribute to increased cardiovascular risk in patients with CKD who exhibit chronic systemic…”
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Primary Occurrence of Cardiovascular Events After Adding Sodium-Glucose Cotransporter-2 Inhibitors or Glucagon-like Peptide-1 Receptor Agonists Compared With Dipeptidyl Peptidase-4 Inhibitors: A Cohort Study in Veterans With Diabetes by Richardson, Jr, Tadarro L, Halvorson, Alese E, Hackstadt, Amber J, Hung, Adriana M, Greevy, Robert, Grijalva, Carlos G, Elasy, Tom A, Roumie, Christianne L

“…The effectiveness of glucagon-like peptide-1 receptor agonists (GLP1RA) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) in preventing major adverse…”
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The Use of a Multidimensional Measure of Dialysis Adequacy-Moving beyond Small Solute Kinetics by Perl, Jeffrey, Dember, Laura M, Bargman, Joanne M, Browne, Teri, Charytan, David M, Flythe, Jennifer E, Hickson, LaTonya J, Hung, Adriana M, Jadoul, Michel, Lee, Timmy Chang, Meyer, Klemens B, Moradi, Hamid, Shafi, Tariq, Teitelbaum, Isaac, Wong, Leslie P, Chan, Christopher T

“…Urea removal has become a key measure of the intensity of dialysis treatment for kidney failure. Small solute removal, exemplified by Kt/V has been broadly…”
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Dialysate and Serum Potassium in Hemodialysis by Hung, Adriana M., MD, MPH, Hakim, Raymond M., MD, PhD

“…Most patients with end-stage renal disease depend on intermittent hemodialysis to maintain levels of serum potassium and other electrolytes within a normal…”
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Estimating Baseline Kidney Function in Hospitalized Patients with Impaired Kidney Function by Siew, Edward D, Ikizler, T Alp, Matheny, Michael E, Shi, Yaping, Schildcrout, Jonathan S, Danciu, Ioana, Dwyer, Jamie P, Srichai, Manakan, Hung, Adriana M, Smith, James P, Peterson, Josh F

“…Inaccurate determination of baseline kidney function can misclassify acute kidney injury (AKI) and affect the study of AKI-related outcomes. No consensus…”
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Validation of an algorithm to identify fractures among patients within the Veterans Health Administration by Horton, Thomas G., Richardson, Tadarro L., Hackstadt, Amber J., Halvorson, Alese E., Hung, Adriana M., Greevy, Robert, Roumie, Christianne L.

“…Objective To validate an algorithm that identifies fractures using billing codes from the International Classification of Diseases Ninth Revision (ICD‐9) and…”
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Comparative Safety of Sulfonylurea and Metformin Monotherapy on the Risk of Heart Failure: A Cohort Study by Roumie, Christianne L, Min, Jea Young, D'Agostino McGowan, Lucy, Presley, Caroline, Grijalva, Carlos G, Hackstadt, Amber J, Hung, Adriana M, Greevy, Robert A, Elasy, Tom, Griffin, Marie R

“…Medications that impact insulin sensitivity or cause weight gain may increase heart failure risk. Our aim was to compare heart failure and cardiovascular death…”
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Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study by Jiang, Lan, Liu, Ge, Oeser, Annette, Ihegword, Andrea, Dickson, Alyson L, Daniel, Laura L, Hung, Adriana M, Cox, Nancy J, Chung, Cecilia P, Wei, Wei-Qi, Stein, C Michael, Feng, Qiping

“…Two risk variants in the apolipoprotein L1 gene ( ) have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear…”
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Comparative effectiveness of incident oral antidiabetic drugs on kidney function by Hung, Adriana M, Roumie, Christianne L, Greevy, Robert A, Liu, Xulei, Grijalva, Carlos G, Murff, Harvey J, Ikizler, T Alp, Griffin, Marie R

“…Diabetes is a major cause of chronic kidney disease, and oral antidiabetic drugs are the mainstay of therapy for most patients with Type 2 diabetes. Here we…”
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Hospitalization for Heart Failure Among Patients With Diabetes Mellitus and Reduced Kidney Function Treated With Metformin Versus Sulfonylureas: A Retrospective Cohort Study by Richardson, Jr, Tadarro L, Hackstadt, Amber J, Hung, Adriana M, Greevy, Robert A, Grijalva, Carlos G, Griffin, Marie R, Elasy, Tom A, Roumie, Christianne L

“…Background Metformin and sulfonylurea are commonly prescribed oral medications for type 2 diabetes mellitus. The association of metformin and sulfonylureas on…”
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Evaluation of Genetic Associations with Clinical Phenotypes of Kidney Stone Disease by Hsi, Ryan S., Zhang, Siwei, Triozzi, Jefferson L., Hung, Adriana M., Xu, Yaomin, Bejan, Cosmin A.

“…From a large-scale electronic health record, we replicate kidney stone disease risk loci within UMOD (16p12.3). We demonstrate differences in stone composition…”
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In Reply to ‘Dialysate and Serum Potassium in Hemodialysis’ by Hung, Adriana M., MD, MPH, Hakim, Raymond M., MD, PhD

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Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study by Bock, Fabian, Stewart, Thomas G, Robinson-Cohen, Cassianne, Morse, Jennifer, Kabagambe, Edmond K, Cavanaugh, Kerri L, Birdwell, Kelly A, Hung, Adriana M, Abdel-Kader, Khaled, Siew, Edward D, Akwo, Elvis A, Blot, William J, Ikizler, T Alp, Lipworth, Loren

“…The Southern Community Cohort Study is a prospective study of low socioeconomic status (SES) blacks and whites from the southeastern US, where the burden of…”
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Laboratory test surveillance following acute kidney injury by Matheny, Michael E, Peterson, Josh F, Eden, Svetlana K, Hung, Adriana M, Speroff, Theodore, Abdel-Kader, Khaled, Parr, Sharidan K, Ikizler, T Alp, Siew, Edward D

“…Patients with hospitalized acute kidney injury (AKI) are at increased risk for accelerated loss of kidney function, morbidity, and mortality. We sought to…”
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A Comparison of Novel and Commonly-Used Indices of Insulin Sensitivity in African American Chronic Hemodialysis Patients by Hung, Adriana M, Sundell, Mary B, Egbert, Phyllis, Siew, Edward D, Shintani, Ayumi, Ellis, Charles D, Bian, Aihua, Ikizler, T Alp

“…Insulin resistance (IR) is highly prevalent in chronic hemodialysis (CHD) patients and is associated with poor cardiovascular outcomes. Hyperinsulinemic…”
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Pharmacogenetic variants and risk of remdesivir‐associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID‐19 by Tuteja, Sony, Yu, Zhihong, Wilson, Otis, Chen, Hua‐Chang, Wendt, Frank, Chung, Cecilia P., Shah, Shailja C., Hunt, Christine M., Suzuki, Ayako, Chanfreau, Catherine, Gorman, Bryan R., Joseph, Jacob, Luoh, Shiuh‐Wen, Napolioni, Valerio, Robinson‐Cohen, Cassianne, Tao, Ran, Zhou, Jin, Chang, Kyong‐Mi, Hung, Adriana M.

“…Remdesivir is the first US Food and Drug Administration (FDA)‐approved drug for the treatment of coronavirus disease 2019 (COVID‐19). We conducted a…”
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Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity by Daniel, Laura L., Dickson, Alyson L., Zanussi, Jacy T., Miller‐Fleming, Tyne W., Straub, Peter S., Wei, Wei‐Qi, Plummer, W. Dale, Dupont, William D., Liu, Ge, Anandi, Prathima, Reese, Tyler S., Birdwell, Kelly A., Kawai, Vivian K., Hung, Adriana M., Cox, Nancy J., Feng, QiPing, Stein, C. Michael, Chung, Cecilia P.

“…TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could…”
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A Description of Risk Factors for Non-alcoholic Fatty Liver Disease in the Southern Community Cohort Study: A Nested Case-Control Study by Sarkar, Sudipa, Lipworth, Loren, Kabagambe, Edmond K., Bian, Aihua, Stewart, Thomas G., Blot, William J., Ikizler, T. Alp, Hung, Adriana M.

“…Background: Non-alcoholic fatty liver disease (NAFLD) is associated with obesity and hypercholesterolemia. In addition, total fat and folate intake have been…”
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