Search Results - "Hundt, Nikolas"

Quantitative mass imaging of single biological macromolecules by Young, Gavin, Hundt, Nikolas, Cole, Daniel, Fineberg, Adam, Andrecka, Joanna, Tyler, Andrew, Olerinyova, Anna, Ansari, Ayla, Marklund, Erik G, Collier, Miranda P, Chandler, Shane A, Tkachenko, Olga, Allen, Joel, Crispin, Max, Billington, Neil, Takagi, Yasuharu, Sellers, James R, Eichmann, Cédric, Selenko, Philipp, Frey, Lukas, Riek, Roland, Galpin, Martin R, Struwe, Weston B, Benesch, Justin L P, Kukura, Philipp

“…The cellular processes underpinning life are orchestrated by proteins and their interactions. The associated structural and dynamic heterogeneity, despite…”
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Mass-sensitive particle tracking to elucidate the membrane-associated MinDE reaction cycle by Heermann, Tamara, Steiert, Frederik, Ramm, Beatrice, Hundt, Nikolas, Schwille, Petra

“…In spite of their great importance in biology, methods providing access to spontaneous molecular interactions with and on biological membranes have been…”
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McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation by Hajdusits, Bence, Suskiewicz, Marcin J, Hundt, Nikolas, Meinhart, Anton, Kurzbauer, Robert, Leodolter, Julia, Kukura, Philipp, Clausen, Tim

“…In Gram-positive bacteria, the McsB protein arginine kinase is central to protein quality control, labeling aberrant molecules for degradation by the ClpCP…”
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Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2 by Hundt, Nikolas, Steffen, Walter, Pathan-Chhatbar, Salma, Taft, Manuel H., Manstein, Dietmar J.

“…Tropomyosin isoforms play an important role in the organisation of cytoplasmic actomyosin complexes in regard to function and cellular localisation. In…”
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FluoroTensor: Identification and tracking of colocalised molecules and their stoichiometries in multi-colour single molecule imaging via deep learning by Wills, Max F.K., Alejo, Carlos Bueno, Hundt, Nikolas, Santana-Vega, Marina, Taladriz-Sender, Andrea, Clark, Alasdair W., Hudson, Andrew J., Eperon, Ian C.

“…The identification of photobleaching steps in single molecule fluorescence imaging is a well-established procedure for analysing the stoichiometries of…”
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Global fit analysis of myosin-5b motility reveals thermodynamics of Mg2+-sensitive acto-myosin-ADP states by Chizhov, Igor, Hartmann, Falk K, Hundt, Nikolas, Tsiavaliaris, Georgios

“…Kinetic and thermodynamic studies of the mechanochemical cycle of myosin motors are essential for understanding the mechanism of energy conversion. Here, we…”
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Mass-Sensitive Particle Tracking to Characterize Membrane-Associated Macromolecule Dynamics by Steiert, Frederik, Heermann, Tamara, Hundt, Nikolas, Schwille, Petra

“…Short-lived or transient interactions of macromolecules at and with lipid membranes, an interface where a multitude of essential biological reactions take…”
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Quantitative Mass Imaging of Actin Nucleation by Hundt, Nikolas, Young, Gavin, Cole, Daniel, Hantke, Max, Kukura, Philipp

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Interferometric Scattering Mass Spectrometry (ISCAMS): Single Molecule Mass Imaging in Solution by Cole, Daniel, Young, Gavin, Hundt, Nikolas, Kukura, Philipp

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Myosin II Filament Dynamics in Actin Networks Revealed with Interferometric Scattering Microscopy by Mosby, Lewis S., Hundt, Nikolas, Young, Gavin, Fineberg, Adam, Polin, Marco, Mayor, Satyajit, Kukura, Philipp, Köster, Darius V.

“…The plasma membrane and the underlying cytoskeletal cortex constitute active platforms for a variety of cellular processes. Recent work has shown that the…”
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Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro by Pathan-Chhatbar, Salma, Taft, Manuel H., Reindl, Theresia, Hundt, Nikolas, Latham, Sharissa L., Manstein, Dietmar J.

“…The metazoan actin cytoskeleton supports a wide range of contractile and transport processes. Recent studies have shown how the dynamic association with…”
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Label-Free Visualisation of Actin Nucleation and Polymerisation at the Single-Molecule Level using Interferometric Scattering Microscopy by Hundt, Nikolas, Tyler, Andrew, Young, Gavin, Cole, Daniel, Fineberg, Adam J., Andrecka, Joanna, Kukura, Philipp

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Direct Observation of Oligomeric Protein (Dis)Assembly and Drug-Induced Cross-Linking at the Single Molecule Level with Interferometric Scattering Mass Spectrometry (ISCAMS) by Young, Gavin, Hundt, Nikolas, Olerinyova, Anna, Ansari, Ayla, Cole, Daniel, Kukura, Philipp

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How the pArg protein mark keeps the stress response kinase MCSB under control by Hajdusits, Bence, Suskiewicz, Martin J., Hundt, Nikolas, Meinhart, Anton, Kukura, Philipp, Clausen, Tim

“…Abstract only…”
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Molecular mechanisms of disease‐related human β‐actin mutations p.R183W and p.E364K by Hundt, Nikolas, Preller, Matthias, Swolski, Olga, Ang, Angella M, Mannherz, Hans G, Manstein, Dietmar J, Müller, Mirco

“…Cytoplasmic β‐actin supports fundamental cellular processes in healthy and diseased cells including cell adhesion, migration, cytokinesis and maintenance of…”
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Direct observation of the molecular mechanism underlying protein polymerization by Hundt, Nikolas, Cole, Daniel, Hantke, Max F, Miller, Jack J, Struwe, Weston B, Kukura, Philipp

“…Protein assembly is a main route to generating complexity in living systems. Revealing the relevant molecular details is challenging because of the intrinsic…”
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Functional Characterization of Disease-Related Human β-Actin Mutants by Hundt, Nikolas, Müller, Mirco, Swolski, Olga, Manstein, Dietmar J.

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Global Fit Analysis of Myosin-5b Motility Reveals Thermodynamics of Mg.sup.2+-Sensitive Acto-Myosin-ADP States by Chizhov, Igor, Hartmann, Falk K, Hundt, Nikolas, Tsiavaliaris, Georgios

“…Kinetic and thermodynamic studies of the mechanochemical cycle of myosin motors are essential for understanding the mechanism of energy conversion. Here, we…”
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Direct Single Molecule Observations of the Unique Mechanical State of Human Myosin-6 by Takagi, Yasuharu, Hundt, Nikolas, Billington, Neil, Andrecka, Joanna, Cole, Daniel, Fineberg, Adam J., Katagiri, Noriko, Bird, Jonathan E., Friedman, Thomas B., Kukura, Philipp, Sellers, James R.

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Structural and Functional Characterization of Nonmuscle Myosin-2B in the Presence of Regulated Actin Filaments by Pathan-Chhatbar, Salma, Münnich, Stefan, Hundt, Nikolas, Taft, Manuel, Manstein, Dietmar

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