Search Results - "Hun, Michael L"
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Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging
Published in Cell reports (Cambridge) (25-06-2019)“…A key feature of immune functional impairment with age is the progressive involution of thymic tissue responsible for naive T cell production. In this study,…”
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The anti-cancer immune response in breast cancer: current and emerging biomarkers and treatments
Published in Trends in cancer (01-06-2024)“…Triple-negative breast cancers (TNBCs) exhibit heightened T cell infiltration, contributing to an enhanced response to immune checkpoint blockade (ICB)…”
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The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
Published in Cell metabolism (06-08-2024)“…A mechanistic connection between aging and development is largely unexplored. Through profiling age-related chromatin and transcriptional changes across 22…”
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A novel Foxn1eGFP/+ mouse model identifies Bmp4‐induced maintenance of Foxn1 expression and thymic epithelial progenitor populations
Published in European journal of immunology (01-02-2017)“…Although forkhead‐box n1 (Foxn1) is a critical thymic epithelial cell regulator in thymus organogenesis, its association with epithelial differentiation and…”
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5
In situ-forming click-crosslinked gelatin based hydrogels for 3D culture of thymic epithelial cells
Published in Biomaterials science (21-07-2016)“…Hydrogels prepared from naturally derived gelatin can provide a suitable environment for cell attachment and growth, making them favourable materials in tissue…”
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Gelatin-Based 3D Microgels for In Vitro T Lineage Cell Generation
Published in ACS biomaterials science & engineering (13-04-2020)“…T cells are predominantly produced by the thymus and play a significant role in maintaining our adaptive immune system. Physiological involution of the thymus…”
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7
A novel Foxn1 eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations
Published in European journal of immunology (01-02-2017)“…Although forkhead-box n1 (Foxn1) is a critical thymic epithelial cell regulator in thymus organogenesis, its association with epithelial differentiation and…”
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Journal Article -
8
A novel Foxn1 super(eGFP/+) mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations
Published in European journal of immunology (01-02-2017)“…Although forkhead-box n1 (Foxn1) is a critical thymic epithelial cell regulator in thymus organogenesis, its association with epithelial differentiation and…”
Get full text
Journal Article