Search Results - "Humphries, William H."

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    Endo-lysosomal vesicles positive for Rab7 and LAMP1 are terminal vesicles for the transport of dextran by Humphries, 4th, William H, Szymanski, Craig J, Payne, Christine K

    Published in PloS one (24-10-2011)
    “…The endo-lysosomal pathway is essential for intracellular transport and the degradation of extracellular cargo. The relationship between three populations of…”
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    Imaging lysosomal enzyme activity in live cells using self-quenched substrates by Humphries, William H., Payne, Christine K.

    Published in Analytical biochemistry (15-05-2012)
    “…Endocytosis, the internalization and transport of extracellular cargo, is an essential cellular process. The ultimate step in endocytosis is the intracellular…”
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    pH-Dependent cis → trans Isomerization Rates for Azobenzene Dyes in Aqueous Solution by Dunn, Nicholas J, Humphries, William H, Offenbacher, Adam R, King, Travis L, Gray, Jeffrey A

    “…Azobenzenes can function as molecular switches driven by their unusual cis ↔ trans photoisomerization properties. The stability of an azobenzene-based switch…”
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    Analyzing cell physiology in C. elegans with fluorescent ratiometric reporters by Wang, Hongning, Karadge, Uma, Humphries, William H., Fisher, Alfred L.

    Published in Methods (San Diego, Calif.) (01-08-2014)
    “…Ratiometric fluorescent reporters have recently emerged a new technique to non-invasively measure aspects of cell physiology such as redox status, calcium…”
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    Cellular binding, motion, and internalization of synthetic gene delivery polymers by Hess, Gaelen T., Humphries, William H., Fay, Nicole C., Payne, Christine K.

    Published in Biochimica et biophysica acta (01-10-2007)
    “…Using fluorescence microscopy we have tracked the cellular binding, surface motion, and internalization of polyarginine and polyethylenimine, cationic ligands…”
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    Single particle tracking as a method to resolve differences in highly colocalized proteins by Szymanski, Craig J, Humphries, 4th, William H, Payne, Christine K

    Published in Analyst (London) (07-09-2011)
    “…Single particle tracking fluorescence microscopy was used to study two late endosomal proteins, Rab7 and LAMP1, that appear to be highly colocalized in static…”
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    Intracellular degradation of low-density lipoprotein probed with two-color fluorescence microscopy by Humphries, 4th, William H, Fay, Nicole C, Payne, Christine K

    Published in Integrative biology (Cambridge) (01-10-2010)
    “…The intracellular vesicle-mediated degradation of extracellular cargo is an essential cellular function. Using two-color single particle tracking fluorescence…”
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    Pyrenebutyrate-Mediated Delivery of Quantum Dots across the Plasma Membrane of Living Cells by Jablonski, Amy E, Humphries, William H, Payne, Christine K

    Published in The journal of physical chemistry. B (15-01-2009)
    “…Quantum dots have been delivered directly across the plasma membrane to the cytosol of living cells using a combination of a cationic peptide, polyarginine,…”
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    Fluorescent Coumarin Thiols Measure Biological Redox Couples by Reddie, Khalilah G, Humphries, William H, Bain, Charlo P, Payne, Christine K, Kemp, Melissa L, Murthy, Niren

    Published in Organic letters (03-02-2012)
    “…In this report we present a new chemical probe, 3-HTC, that can reversibly and ratiometrically measure the thiol-disulfide equilibrium of biological systems…”
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    P‐Glycoprotein‐Dependent Trafficking of Nanoparticle‐Drug Conjugates by Dreaden, Erik C., Raji, Idris O., Austin, Lauren A., Fathi, Shaghayegh, Mwakwari, Sandra C., Humphries, William H., Kang, Bin, Oyelere, Adegboyega K., El‐Sayed, Mostafa A.

    “…P‐glycoprotein (P‐gp) is considered to be the most prevalent and single most important cause of multidrug‐resistance (MDR) in humans. Although the protein is…”
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    Intracellular degradation of low-density lipoprotein probed with two-color fluorescence microscopyElectronic supplementary information (ESI) available: Figures S1-S4. See DOI: 10.1039/c0ib00035c by Humphries IV, William H, Fay, Nicole C, Payne, Christine K

    Published 04-10-2010
    “…The intracellular vesicle-mediated degradation of extracellular cargo is an essential cellular function. Using two-color single particle tracking fluorescence…”
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    Journal Article