Search Results - "Humpe, Andreas"
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Bridge Inspection with an Off-the-Shelf 360° Camera Drone
Published in Drones (Basel) (01-12-2020)“…The author proposes a new approach for bridge crack detection by a 360° camera on top of a drone. Traditionally, bridge inspection is performed manually and…”
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COVID-19 and pathways to low-carbon air transport until 2050
Published in Environmental research letters (01-03-2021)“…Abstract The COVID-19 pandemic has led to an unprecedented decline in global air transport and associated reduction in CO 2 emissions. The International Civil…”
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The social cost of carbon falling on the wealthy
Published in Cleaner Production Letters (01-12-2024)“…Under the Paris Agreement, the responsibility for reducing greenhouse gas emissions lies with individual countries, which submit pledges to the United Nations…”
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Millionaire spending incompatible with 1.5 °C ambitions
Published in Cleaner Production Letters (01-06-2023)“…Much evidence suggests that the wealthiest individuals contribute disproportionally to climate change. Here we study the implications of a continued growth in…”
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Private aviation is making a growing contribution to climate change
Published in Communications earth & environment (07-11-2024)“…Commercial aviation’s contribution to climate change is growing, but the global role of private aviation is not well quantified. Here we calculate the sector’s…”
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Perspectives of targeting LILRB1 in innate and adaptive immune checkpoint therapy of cancer
Published in Frontiers in immunology (13-09-2023)“…Immune checkpoint blockade is a compelling approach in tumor immunotherapy. Blocking inhibitory pathways in T cells has demonstrated clinical efficacy in…”
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Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses
Published in Nature methods (01-01-2022)“…CD4 + T cells are central mediators of adaptive and innate immune responses and constitute a major reservoir for human immunodeficiency virus (HIV) in vivo…”
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High-Risk HLA-DQ Mismatches Are Associated With Adverse Outcomes After Lung Transplantation
Published in Transplant international (19-09-2024)“…Human leukocyte antigen (HLA) mismatches (MM) between donor and recipient lead to eplet MM (epMM) in lung transplantation (LTX), which can induce the…”
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Impact, Screening, and Therapy of HLA Antibodies in Patients before and after Lung Transplantation
Published in Transfusion medicine and hemotherapy (01-10-2019)“…Since almost 30 years, lung transplantation is a considerable therapeutic option in patients suffering from end-stage lung disease. Up to now, the impact of…”
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Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages
Published in Frontiers in immunology (27-10-2022)“…Antibody-dependent cellular phagocytosis (ADCP) by macrophages, an important effector function of tumor targeting antibodies, is hampered by ‘Don´t Eat Me!’…”
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Keeping older people mobile: Autonomous transport services in rural areas
Published in Transportation research interdisciplinary perspectives (01-03-2023)“…•Investigates interrelationships of ATS acceptance and old age.•Finds considerable support for ATS, though this declines with age.•Shows that neither price nor…”
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Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions
Published in Cancer science (01-08-2021)“…Integrin associated protein (CD47) is an important target in immunotherapy, as it is expressed as a “don't eat me” signal on many tumor cells. Interference…”
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Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells
Published in Frontiers in immunology (27-10-2023)“…The activating receptor natural killer group 2, member D (NKG2D) represents an attractive target for immunotherapy as it exerts a crucial role in cancer…”
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SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells
Published in Journal of hematology and oncology (27-09-2021)“…Abstract Background Acute myeloid leukaemia (AML) stem cells (LSCs) cause disease relapse. The CD47 “don’t eat me signal” is upregulated on LSCs and…”
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Macroeconomic variables and long-term stock market performance: A panel ARDL cointegration approach for G7 countries
Published in Cogent economics & finance (2020)“…Based on the present value model for stock prices, we utilise a pooled mean group estimator for panel ARDL cointegration to estimate the long-run relationship…”
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Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade
Published in HemaSphere (01-02-2024)“…CD19‐directed immunotherapy has become a cornerstone in the therapy of B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). CD19‐directed cellular and…”
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Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering
Published in Antibodies (Basel) (17-11-2020)“…Background: Native cluster of differentiation (CD) 19 targeting antibodies are poorly effective in triggering antibody-dependent cell-mediated cytotoxicity…”
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A clinically-feasible protocol for using human platelet lysate and mesenchymal stem cells in regenerative therapies
Published in Journal of cranio-maxillo-facial surgery (01-03-2013)“…Abstract The transplantation of human stem cells seeded on biomaterials holds promise for many clinical applications in cranio-maxillo-facial tissue…”
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Enhanced ADCC activity of affinity maturated and Fc-engineered mini-antibodies directed against the AML stem cell antigen CD96
Published in PloS one (03-08-2012)“…CD96, a cell surface antigen recently described to be preferentially expressed on acute myeloid leukemia (AML) leukemic stem cells (LSC) may represent an…”
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Temporary stock market bubbles: further evidence from Germany
Published in Investment management & financial innovations (2015)Get full text
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