Search Results - "Humpe, A."

Cell recruitment and collection yields in autologous MNC apheresis by Wagner, B, Subklewe, M, Albert, M.H, Feuchtinger, T, von Bergwelt, M, Humpe, A

“…Background & AimAutologous MNC apheresis is applied for the preparation of various advanced therapy medicinal products (ATMPs) for immunotherapy of cancer. The…”
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CD20‐Specific Immunoligands Engaging NKG2D Enhance γδ T Cell‐Mediated Lysis of Lymphoma Cells by Peipp, M., Wesch, D., Oberg, H.‐H., Lutz, S., Muskulus, A., Winkel, J. G. J., Parren, P. W. H. I., Burger, R., Humpe, A., Kabelitz, D., Gramatzki, M., Kellner, C.

“…Human γδ T cells are innate‐like T cells which are able to kill a broad range of tumour cells and thus may have potential for cancer immunotherapy. The…”
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The Fc-engineered CD19 antibody MOR208 (XmAb5574) induces natural killer cell-mediated lysis of acute lymphoblastic leukemia cells from pediatric and adult patients by Kellner, C, Zhukovsky, E A, Pötzke, A, Brüggemann, M, Schrauder, A, Schrappe, M, Kneba, M, Repp, R, Humpe, A, Gramatzki, M, Peipp, M

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Dental status does not predict infection during stem cell transplantation: a single-center survey by Guenther, A, Losch, E, Schiessl, M, Schrauder, A, Humpe, A, Repp, R, Nitsche, T, Wiltfang, J, Gramatzki, M

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Regulation of advanced therapy medicinal products will affect the practice of haematopoietic SCT in the near future: a perspective from the EBMT cell-processing committee by Chabannon, C, Hildebrandt, M, Scheding, S, Humpe, A, Lowdell, M, Slaper-Cortenbach, I

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The novel tribody [(CD20)2xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells by Glorius, P, Baerenwaldt, A, Kellner, C, Staudinger, M, Dechant, M, Stauch, M, Beurskens, F J, Parren, P W H I, Winkel, J G J van de, Valerius, T, Humpe, A, Repp, R, Gramatzki, M, Nimmerjahn, F, Peipp, M

“…Bispecific antibodies (bsab) offer a promising approach for optimizing antibody-based therapies. In the present study, [(CD20) 2 xCD16], a recombinant CD20-…”
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EXTRANODAL DISEASE IS ASSOCIATED WITH SHORTER PROGRESSION‐FREE SURVIVAL AFTER CD19‐CAR T‐CELL THERAPY FOR RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA by Bücklein, V., Blumenberg, V., Ackermann, J., Frölich, L., Winkelmann, M., Schmidt, C., Rejeski, K., Ruzicka, M., Müller, N., von Baumgarten, L., Schöberl, F., Hildebrandt, M., Humpe, A., Kunz, W., Hoster, E., von Bergwelt, M., Subklewe, M.

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Quantitative MRD monitoring identifies distinct GVL response patterns after allogeneic stem cell transplantation for chronic lymphocytic leukemia: results from the GCLLSG CLL3X trial by Ritgen, M, Böttcher, S, Stilgenbauer, S, Bunjes, D, Schubert, J, Cohen, S, Humpe, A, Hallek, M, Kneba, M, Schmitz, N, Döhner, H, Dreger, P

“…The purpose of this study was to prospectively analyze minimal residual disease(MRD) kinetics after reduced-intensity allogeneic stem cell transplantation…”
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Fusion proteins between ligands for NKG2D and CD20-directed single-chain variable fragments sensitize lymphoma cells for natural killer cell-mediated lysis and enhance antibody-dependent cellular cytotoxicity by Kellner, C, Hallack, D, Glorius, P, Staudinger, M, Mohseni Nodehi, S, de Weers, M, van de Winkel, J G J, Parren, P W H I, Stauch, M, Valerius, T, Repp, R, Humpe, A, Gramatzki, M, Peipp, M

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Direct volumetric flow cytometric quantitation of CD34+ stem and progenitor cells by Gutensohn, K., Nikolitsis, A., Gramatzki, M., Spitzer, D., Buwitt-Beckmann, U., Humpe, A.

“…Objectives: In this study, we compared a classic single‐platform (SP) method applying beads for enumeration of CD45+ or CD34+ cells with a new device allowing…”
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Establishment and optimization of a flow cytometric method for evaluation of viability of CD34+ cells after cryopreservation and comparison with trypan blue exclusion staining by Humpe, Andreas, Beck, Christian, Schoch, Robert, Kneba, Michael, Horst, Heinz‐August

“…BACKGROUND:  Trypan blue exclusion staining is probably the most frequently applied method (Method I) for assessment of viability in peripheral blood…”
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Quality controls of cryopreserved haematopoietic progenitor cells (peripheral blood, cord blood, bone marrow) by Rosskopf, K., Ragg, S. J., Worel, N., Grommé, M., Preijers, F. W. M. B., Braakman, E., Schuurhuis, G. J., van Riet, I., Wendel, S., Fontão-Wendel, R., Lazar, A., Goldman, M., Halpenny, M., Giulivi, A., Letcher, B., McGann, L., Korhonen, M., Arvola, A., Humpe, A., Buwitt-Beckmann, U., Wiesneth, M., Schauwecker, P., Schrezenmeier, H., Bönig, H., Henschler, R., Seifried, E., Accorsi, P., Bonfini, T., Takanashi, M., van Beckhoven, J. M., Brand, A., Gounder, D., Wong, A., Dooccey, R., Forrest, E., Galea, G., Smythe, J., Pawson, R., Reems, J.-A., Oh, J., Reesink, H. W., Panzer, S.

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Evidence for gene recombination in FCGR3 gene variants by Blum, K. S., Tong, Y., Siebert, R., Marget, M., Humpe, A., Neppert, J., Flesch, B. K.

“…Background and Objectives  The genes encoding the Fcγ receptors (FcγR) IIIa and IIIb (FCGR3A and FCGR3B) are clustered on chromosome 1 band q23–24 and exhibit…”
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Successful autologous hematopoietic progenitor cell transplantation in a patient with an isoantibody against CD36 (glycoprotein IV, Nak ) by Flesch, B, Miller, J, Repp, R, Ott, S, Gahn, B, Schub, N, Gramatzki, M, Humpe, A

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When A is not A anymore: problems and pitfalls with blood group typing by Möhnle, P, Humpe, A, Wittmann, G

“…Correct blood group typing is a prerequisite for transfusion. In most cases blood group determination is without problems; however, in individual cases various…”
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Re-transplantation from the same unrelated donor in three adolescents with severe aplastic anemia after graft rejection by Führer, M, Claviez, A, Klein, B, Humpe, A, Schrauder, A

“…Hematopoietic stem cell transplantation (HSCT) from a matched unrelated donor (MUD) has become the accepted salvage treatment for patients with severe aplastic…”
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Isolated meningeal chloroma (granulocytic sarcoma): a case report and review of the literature by BINDER, C, TIEMANN, M, HAASE, D, HUMPE, A, KNEBA, M

“…Isolated chloromas (granulocytic sarcomas) are rare tumors, most of them progressing to acute myeloblastic leukemia within months. There are still no…”
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Proliferation-based T-cell selection for immunotherapy and graft-versus-host-disease prophylaxis in the context of bone marrow transplantation by PACHNIO, A, DIETRICH, S, KLAPPER, W, HUMPE, A, SCHWAKE, M, SEDLACEK, R, GRAMATZKI, M, BECK, C

“…Graft-versus-host disease (GvHD) caused by alloreactive T cells within the graft is a major drawback of allogeneic BMT, but depletion of T cells leads to…”
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Myelodysplastic syndrome of donor origin subsequent to successful treatment of myeloid/NK-cell precursor leukaemia with allogeneic PBSCT: two very rare conditions in one patient by Beck, C, Humpe, A, Harder, S, Schmid, M, Horst, H A

“…We report a 36-year-old male with myeloid/natural killer (NK)-cell precursor acute leukaemia with a complex aberrant karyotype, who was treated according to an…”
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Oncological impact of perioperative blood transfusion in bladder cancer patients undergoing radical cystectomy: Do we need to consider storage time of blood units, donor age or gender matching? by Ebner, B., Franka, F., Volz, Y., Eismann, L., Hermans, J., Buchner, A., Enzinger, B., Weinhold, P., Wichmann, C., Stief, C.G., Humpe, A., Pyrgidis, N., Schulz, G.B.

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