Search Results - "Hummers, L."

Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension by CAMPO, A, MATHAI, S. C, HASSOUN, P. M, LE PAVEC, J, ZAIMAN, A. L, HUMMERS, L. K, BOYCE, D, HOUSTEN, T, LECHTZIN, N, CHAMI, H, GIRGIS, R. E

“…The aim of this study was to examine the causes and outcomes of hospitalisation in patients with pulmonary arterial hypertension (PAH). 205 consecutive…”
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Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension by Mathai, S. C, Bueso, M, Hummers, L. K, Boyce, D, Lechtzin, N, Le Pavec, J, Campo, A, Champion, H. C, Housten, T, Forfia, P. R, Zaiman, A. L, Wigley, F. M, Girgis, R. E, Hassoun, P. M

“…N-terminal pro-brain natriuretic peptide (NT-proBNP) is a marker of neurohormonal activation that is useful in the diagnosis and prognosis of various forms of…”
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PM-Scl and Th/To in systemic sclerosis: a comparison of different autoantibody assays by Mecoli, C. A., Gutierrez-Alamillo, L., Yang, Q., Sampedro, M., Woods, A., Hummers, L. K., Wigley, F., Shah, A. A., Casciola-Rosen, L.

“…Objective To compare test characteristics of the Euroimmun line blot assay with other assays for two uncommon autoantibody specificities in systemic…”
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A case–control study of the pathology of oesophageal disease in systemic sclerosis (scleroderma) by Roberts, C G P, Hummers, L K, Ravich, W J, Wigley, F M, Hutchins, G M

“…Background: Atrophy of the smooth muscle layers of the muscularis propria characterises oesophageal involvement in systemic sclerosis (scleroderma). The…”
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Proposed diagnostic criteria and nosology of acute transverse myelitis

“…Acute transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic dysfunction. A set of uniform…”
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Biomarkers of vascular disease in scleroderma by Hummers, L. K.

“…Vascular disease is present in every patient with scleroderma and is a major source of morbidity and mortality. There is a subset of patients who will develop…”
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Recurrent transverse myelitis associates with anti-ro (SSA) autoantibodies by HUMMERS, L. K, KRISHNAN, C, CASCIOLA-ROSEN, L, ROSEN, A, MORRIS, S, MAHONEY, J. A, KERR, D. A, WIGLEY, F. M

“…Transverse myelitis (TM) is an idiopathic inflammatory disorder of the spinal cord. The authors observed cases of recurrent TM in patients where anti-Ro (SSA)…”
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High-dose cyclophosphamide without stem cell rescue in scleroderma by Tehlirian, C V, Hummers, L K, White, B, Brodsky, R A, Wigley, F M

“…To investigate the safety and tolerability of high-dose cyclophosphamide without stem cell rescue in scleroderma. An open-label, single-site, uncontrolled…”
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The "tank top sign": a unique pattern of skin fibrosis seen in pansclerotic morphea by Sherber, N S, Boin, F, Hummers, L K, Wigley, F M

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Distinct recognition of antibodies to centromere proteins in primary Sjögren’s syndrome compared with limited scleroderma by Gelber, A C, Pillemer, S R, Baum, B J, Wigley, F M, Hummers, L K, Morris, S, Rosen, A, Casciola-Rosen, L

“…Background: Anticentromere antibodies are characteristically observed in scleroderma but have recently been reported in other autoimmune rheumatic disorders,…”
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Abnormal exhaled ethane concentrations in scleroderma by Cope, K. A., Solga, S. F., Hummers, L. K., Wigley, F. M., Diehl, A. M., Risby, T. H.

“…Abstract Scleroderma (systemic sclerosis) is a chronic multisystem autoimmune disease in which oxidative stress is suspected to play a role in the…”
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Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database by Tyndall, Anthony J, Bannert, Bettina, Vonk, Madelon, Airò, Paolo, Cozzi, Franco, Carreira, Patricia E, Bancel, Dominique Farge, Allanore, Yannick, Müller-Ladner, Ulf, Distler, Oliver, Iannone, Florenzo, Pellerito, Raffaele, Pileckyte, Margarita, Miniati, Irene, Ananieva, Lidia, Gurman, Alexandra Balbir, Damjanov, Nemanja, Mueller, Adelheid, Valentini, Gabriele, Riemekasten, Gabriela, Tikly, Mohammed, Hummers, Laura, Henriques, Maria J S, Caramaschi, Paola, Scheja, Agneta, Rozman, Blaz, Ton, Evelien, Kumánovics, Gábor, Coleiro, Bernard, Feierl, Eva, Szucs, Gabriella, Von Mühlen, Carlos Alberto, Riccieri, Valeria, Novak, Srdan, Chizzolini, Carlo, Kotulska, Anna, Denton, Christopher, Coelho, Paulo C, Kötter, Ina, Simsek, Ismail, de la Pena Lefebvre, Paloma García, Hachulla, Eric, Seibold, James R, Rednic, Simona, Stork, Jirí, Morovic-Vergles, Jadranka, Walker, Ulrich A

“…To determine the causes and predictors of mortality in systemic sclerosis (SSc). Patients with SSc (n=5860) fulfilling the American College of Rheumatology…”
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Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases by Acosta-Herrera, Marialbert, Kerick, Martin, González-Serna, David, Wijmenga, Cisca, Franke, Andre, Gregersen, Peter K, Padyukov, Leonid, Worthington, Jane, Vyse, Timothy James, Alarcón-Riquelme, Marta Eugenia, Mayes, Maureen D, Martin, Javier

“…Immune-mediated inflammatory diseases (IMIDs) are heterogeneous and complex conditions with overlapping clinical symptoms and elevated familial aggregation,…”
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Progression of Interstitial Lung Disease in Systemic Sclerosis: The Importance of Pneumoproteins Krebs von den Lungen 6 and CCL18 by Volkmann, Elizabeth R., Tashkin, Donald P., Kuwana, Masataka, Li, Ning, Roth, Michael D., Charles, Julio, Hant, Faye N., Bogatkevich, Galina S., Akter, Tanjina, Kim, Grace, Goldin, Jonathan, Khanna, Dinesh, Clements, Philip J., Furst, Daniel E., Elashoff, Robert M., Silver, Richard M., Assassi, Shervin, Theodore, A. C., Simms, R. W., Kissin, E., Cheong, F. Y., Steen, V. D., Read, C. A., Fridley, C., Zulmatashvili, M., Wise, R. A., Wigley, F. M., Hummers, L., Leatherman, G., Silver, R. M., Strange, C., Hant, F. N., Ham, J., Gibson, K., Rosson, D., Tashkin, D. P., Elashoff, R. M., Roth, M. D., Clements, P. J., Furst, D., Volkmann, E. R., Kafaja, S., Kleerup, E., Elashoff, D., Goldin, J., Ariola, E., Marlis, G., Mason‐Berry, J., Saffold, P., Rodriguez, M., Guzman, L., Brook, J., Golden, J., Connolly, M. K., Eller, A., Leong, D., Lalosh, M., Obata, J., Volkov, S., Schraufnagel, D., Arami, S., Franklin, D., Varga, J., Dematte, J., Hinchcliff, M., DeLuca, C., Donnelly, H., Marlin, C., Riley, D. J., Hsu, V. M., McCloskey, D. A., Phillips, K., Khanna, D., Martinez, F. J., Schiopu, E., Konkle, J., Mayes, M., Patel, B., Assassi, S., Tan, F., Fischer, A., Swigris, J., Meehan, R., Brown, K., Warren, T., Morrison, M., Scholand, M. B., Frecht, T., Carey, P., Villegas, M., Molitor, J., Carlson, P.

“…Objective To investigate the relationship between Krebs von den Lungen 6 (KL‐6) and CCL18 levels and the severity and progression of systemic sclerosis…”
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Distinct clinical trajectories of gastrointestinal progression among patients with systemic sclerosis by Perin, J, Hughes, M, Mecoli, C A, Paik, J J, Gelber, A C, Wigley, F M, Hummers, L K, Shah, A A, Zeger, S L, McMahan, Z H

“…Systemic sclerosis (SSc) is heterogeneous in its clinical presentation. Common manifestations cluster together, defining unique subgroups. This investigation…”
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Troponin elevation independently associates with mortality in systemic sclerosis by Paik, Julie J, Choi, Deborah Y, Mukherjee, Monica, Hsu, Steven, Wigley, Fredrick, Shah, Ami A, Hummers, Laura K

“…Cardiac involvement is common in systemic sclerosis (SSc), and elevated troponin may be the only sign of ongoing myocardial disease. The objective was to…”
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PRS3 Joint Modelling of Forced Vital Capacity Decline and Time to Hospitalization Outcomes in Systemic Sclerosis-Associated Interstitial Lung Disease by Stock, C., Kreuter, M., Del Galdo, F., Miede, C., Khanna, D., Wuyts, W., Hummers, L., Alves, M., Schoof, N., Allanore, Y.

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Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus by Radstake, Timothy R D J, Gorlova, Olga, Rueda, Blanca, Martin, Jose-Ezequiel, Alizadeh, Behrooz Z, Palomino-Morales, Rogelio, Coenen, Marieke J, Vonk, Madelon C, Voskuyl, Alexandre E, Schuerwegh, Annemie J, Broen, Jasper C, van Riel, Piet L C M, van 't Slot, Ruben, Italiaander, Annet, Ophoff, Roel A, Riemekasten, Gabriela, Hunzelmann, Nico, Simeon, Carmen P, Ortego-Centeno, Norberto, González-Gay, Miguel A, González-Escribano, María F, Airo, Paolo, van Laar, Jaap, Herrick, Ariane, Worthington, Jane, Hesselstrand, Roger, Smith, Vanessa, de Keyser, Filip, Houssiau, Fredric, Chee, Meng May, Madhok, Rajan, Shiels, Paul, Westhovens, Rene, Kreuter, Alexander, Kiener, Hans, de Baere, Elfride, Witte, Torsten, Padykov, Leonid, Klareskog, Lars, Beretta, Lorenzo, Scorza, Rafaella, Lie, Benedicte A, Hoffmann-Vold, Anna-Maria, Carreira, Patricia, Varga, John, Hinchcliff, Monique, Gregersen, Peter K, Lee, Annette T, Ying, Jun, Han, Younghun, Weng, Shih-Feng, Amos, Christopher I, Wigley, Fredrick M, Hummers, Laura, Nelson, J Lee, Agarwal, Sandeep K, Assassi, Shervin, Gourh, Pravitt, Tan, Filemon K, Koeleman, Bobby P C, Arnett, Frank C, Martin, Javier, Mayes, Maureen D

“…Timothy Radstake and Maureen Mayes and colleagues report results of a genome-wide association study of systemic sclerosis. They identify a new susceptibility…”
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Effect of Macitentan on the Development of New Ischemic Digital Ulcers in Patients With Systemic Sclerosis: DUAL-1 and DUAL-2 Randomized Clinical Trials by Khanna, Dinesh, Denton, Christopher P, Merkel, Peter A, Krieg, Thomas, Le Brun, Franck-Olivier, Marr, Angelina, Papadakis, Kelly, Pope, Janet, Matucci-Cerinic, Marco, Furst, Daniel E

“…IMPORTANCE: Digital ulcers in patients with systemic sclerosis are associated with pain and poor quality of life. Endothelin-1 promotes vasculopathy in…”
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A randomised, double-blind, placebo-controlled phase 3 study of lenabasum in diffuse cutaneous systemic sclerosis: RESOLVE-1 design and rationale by Spiera, Robert, Khanna, Dinesh, Kuwana, Masataka, Furst, Daniel E, Frech, Tracy M, Hummers, Laura, Stevens, Wendy, Matucci-Cerinic, Marco, Baron, Murray, Distler, Oliver, Dgetluck, Nancy, Bloom, Bradley J, Dinh, Quinn, White, Barbara, Denton, Christopher P

“…The multi-systemic, heterogenous nature of diffuse cutaneous systemic sclerosis (dcSSc) presents challenges in designing clinical studies that can demonstrate…”
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