Search Results - "Hummel, Werner"

Combining the ‘two worlds’ of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media by Gröger, Harald, Hummel, Werner

“…•Combining the “two worlds” biocatalysis and chemocatalysis towards one-pot syntheses in aqueous media is a promising concept for the development of both…”
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Cooperative Catalysis of Noncompatible Catalysts through Compartmentalization: Wacker Oxidation and Enzymatic Reduction in a One-Pot Process in Aqueous Media by Sato, Hirofumi, Hummel, Werner, Gröger, Harald

“…A Wacker oxidation using CuCl/PdCl2 as a catalyst system was successfully combined with an enzymatic ketone reduction to convert styrene enantioselectively…”
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Combination of Asymmetric Organo- and Biocatalytic Reactions in Organic Media Using Immobilized Catalysts in Different Compartments by Heidlindemann, Marcel, Rulli, Giuseppe, Berkessel, Albrecht, Hummel, Werner, Gröger, Harald

“…A proof of concept for the combination of an asymmetric organocatalytic reaction with a biotransformation toward a “one-pot like” process for 1,3-diols based…”
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Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis by Rulli, Giuseppe, Duangdee, Nongnaphat, Baer, Katrin, Hummel, Werner, Berkessel, Albrecht, Gröger, Harald

“…The catalyst loading in the narrow range between 0.5 and 10 mol % determines whether an enantioselective organocatalytic aldol reaction proceeds under kinetic…”
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Formal Asymmetric Hydration of Non-Activated Alkenes in Aqueous Medium through a "Chemoenzymatic Catalytic System" by Schnapperelle, Ingo, Hummel, Werner, Gröger, Harald

“…A direct one‐pot conversion of (substituted) styrene(s) into the corresponding (substituted) (R)‐phenylethan‐1‐ol(s) in a highly enantioselective manner has…”
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Guerbet Alcohols: From Processes under Harsh Conditions to Synthesis at Room Temperature under Ambient Pressure by Biermann, Marc, Gruß, Hendrik, Hummel, Werner, Gröger, Harald

“…A novel synthetic approach towards Guerbet alcohols, which are important intermediates in the production of plasticizers, lubricants, and surfactants, was…”
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Characterization of a whole-cell catalyst co-expressing glycerol dehydrogenase and glucose dehydrogenase and its application in the synthesis of L-glyceraldehyde by Richter, Nina, Neumann, Markus, Liese, Andreas, Wohlgemuth, Roland, Weckbecker, Andrea, Eggert, Thorsten, Hummel, Werner

“…A whole-cell catalyst using Escherichia coli BL21(DE3) as a host, co-expressing glycerol dehydrogenase (GlyDH) from Gluconobacter oxydans and glucose…”
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The Organic-Synthetic Potential of Recombinant Ene Reductases: Substrate-Scope Evaluation and Process Optimization by Reß, Tina, Hummel, Werner, Hanlon, Steven P., Iding, Hans, Gröger, Harald

“…In this study an evaluation of the synthetic potential of a broad range of recombinant ene reductases was performed. In detail, a library of 23 ene reductases…”
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The Structure of a Bacterial l-Amino Acid Oxidase from Rhodococcus opacus Gives New Evidence for the Hydride Mechanism for Dehydrogenation by Faust, Annette, Niefind, Karsten, Hummel, Werner, Schomburg, Dietmar

“…l-Amino acid oxidase from Rhodococcus opacus (roLAAO) is classified as a member of the GR 2-family of flavin-dependent oxidoreductases according to a highly…”
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Iron Catalysis for In Situ Regeneration of Oxidized Cofactors by Activation and Reduction of Molecular Oxygen: A Synthetic Metalloporphyrin as a Biomimetic NAD(P)H Oxidase by Maid, Harald, Böhm, Philipp, Huber, Stefan M, Bauer, Walter, Hummel, Werner, Jux, Norbert, Gröger, Harald

“…An enzyme substitute: A synthetic FeIII porphyrin was used as a catalyst for the activation and reduction of O2 into H2O with the cofactor NAD(P)H in aqueous…”
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Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile by Daniel Bakonyi, Christine Toelzer, Michael Stricker, Werner Hummel, Karsten Niefind, Harald Gröger

“…Alcohol dehydrogenases catalyse the conversion of a large variety of ketone substrates to the corresponding chiral products. Due to their high regio- and…”
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The Three-Dimensional Structure of AKR11B4, a Glycerol Dehydrogenase from Gluconobacter oxydans, Reveals a Tryptophan Residue as an Accelerator of Reaction Turnover by Richter, Nina, Breicha, Klaus, Hummel, Werner, Niefind, Karsten

“…The NADP-dependent glycerol dehydrogenase (EC 1.1.1.72) from Gluconobacter oxydans is a member of family 11 of the aldo–keto reductase (AKR) enzyme…”
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Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity by Schlieben, Nils Helge, Niefind, Karsten, Müller, Jörg, Riebel, Bettina, Hummel, Werner, Schomburg, Dietmar

“…The R-specific alcohol dehydrogenase (RADH) from Lactobacillus brevis is an NADP-dependent, homotetrameric member of the extended enzyme family of short-chain…”
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Enantio- and Diastereoselective Chemoenzymatic Synthesis of C2-Symmetric Biaryl-Containing Diols by Burda, Edyta, Bauer, Walter, Hummel, Werner, Gröger, Harald

“…An enantio‐ and diastereoselective synthesis of C2‐symmetric diols bearing a biphenyl‐framework has been developed by means of an enzymatic reduction of the…”
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NADH oxidase from Lactobacillus brevis: a new catalyst for the regeneration of NAD by Geueke, Birgit, Riebel, Bettina, Hummel, Werner

“…The regeneration of NAD was carried out with an NADH oxidase from the gram-positive bacterium Lactobacillus brevis DSM 20 054. High levels of this enzyme are…”
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Enantioselective One-Pot Two-Step Synthesis of Hydrophobic Allylic Alcohols in Aqueous Medium through the Combination of a Wittig Reaction and an Enzymatic Ketone Reduction by Kraußer, Marina, Hummel, Werner, Gröger, Harald

“…A one‐pot two‐step process for the enantioselective synthesis of hydrophobic allylic alcohols was developed, which comprises ketone formation by the Wittig…”
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The Crystal Structure of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Suggests the Structural Basis of its Metal Dependency by Niefind, Karsten, Müller, Jörg, Riebel, Bettina, Hummel, Werner, Schomburg, Dietmar

“…The crystal structure of the apo-form of an R-specific alcohol dehydrogenase from Lactobacillus brevis (LB-RADH) was solved and refined to 1.8 Å resolution…”
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Overproduction and characterization of a recombinant D-amino acid oxidase from Arthrobacter protophormiae by Geueke, Birgit, Weckbecker, Andrea, Hummel, Werner

“…A screening of soil samples for d-amino acid oxidase (d-AAO) activity led to the isolation and identification of the gram-positive bacterium Arthrobacter…”
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Highly Enantioselective Preparation of Multifunctionalized Propargylic Building Blocks by Schubert, Thomas, Hummel, Werner, Müller, Michael

“…Halogenated propargylic alcohol 2 a (X = Cl, R = Ph) was prepared by the enzymatic reduction of the corresponding ketone 1 a with excellent enantioselectivity…”
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Isolation and biochemical characterization of a new NADH oxidase from Lactobacillus brevis by Hummel, W, Riebel, B

“…A new NADH oxidase, useful for the regeneration of NAD+, was isolated and characterized from Lactobacillus brevis. In crude extracts the activity was from…”
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