Search Results - "Hummel, John D"

Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts by Hansen, Brian J, Zhao, Jichao, Csepe, Thomas A, Moore, Brandon T, Li, Ning, Jayne, Laura A, Kalyanasundaram, Anuradha, Lim, Praise, Bratasz, Anna, Powell, Kimerly A, Simonetti, Orlando P, Higgins, Robert S D, Kilic, Ahmet, Mohler, Peter J, Janssen, Paul M L, Weiss, Raul, Hummel, John D, Fedorov, Vadim V

“…The complex architecture of the human atria may create physical substrates for sustained re-entry to drive atrial fibrillation (AF). The existence of…”
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Acute Termination of Human Atrial Fibrillation by Identification and Catheter Ablation of Localized Rotors and Sources: First Multicenter Experience of Focal Impulse and Rotor Modulation (FIRM) Ablation by SHIVKUMAR, KALYANAM, ELLENBOGEN, KENNETH A., HUMMEL, JOHN D., MILLER, JOHN M., STEINBERG, JONATHAN S.

“…FIRM Ablation of Human AF Rotors. Introduction: Catheter ablation of atrial fibrillation (AF) currently relies on eliminating triggers, and no reliable method…”
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Initial Independent Outcomes from Focal Impulse and Rotor Modulation Ablation for Atrial Fibrillation: Multicenter FIRM Registry by MILLER, JOHN M., KOWAL, ROBERT C., SWARUP, VIJAY, DAUBERT, JAMES P., DAOUD, EMILE G., DAY, JOHN D., ELLENBOGEN, KENNETH A., HUMMEL, JOHN D., BAYKANER, TINA, KRUMMEN, DAVID E., NARAYAN, SANJIV M., REDDY, VIVEK Y., SHIVKUMAR, KALYANAM, STEINBERG, JONATHAN S., WHEELAN, KEVIN R.

“…Multicenter FIRM Registry for AF Introduction The success of pulmonary vein isolation (PVI) for atrial fibrillation (AF) may be improved if stable AF sources…”
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Three‐dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural “Fingerprints” of Heart‐Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo by Zhao, Jichao, Hansen, Brian J., Wang, Yufeng, Csepe, Thomas A., Sul, Lidiya V., Tang, Alan, Yuan, Yiming, Li, Ning, Bratasz, Anna, Powell, Kimerly A., Kilic, Ahmet, Mohler, Peter J., Janssen, Paul M. L., Weiss, Raul, Simonetti, Orlando P., Hummel, John D., Fedorov, Vadim V.

“…Background Structural remodeling of human atria plays a key role in sustaining atrial fibrillation (AF), but insufficient quantitative analysis of human atrial…”
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Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure by Li, Ning, Hansen, Brian J, Csepe, Thomas A, Zhao, Jichao, Ignozzi, Anthony J, Sul, Lidiya V, Zakharkin, Stanislav O, Kalyanasundaram, Anuradha, Davis, Jonathan P, Biesiadecki, Brandon J, Kilic, Ahmet, Janssen, Paul M L, Mohler, Peter J, Weiss, Raul, Hummel, John D, Fedorov, Vadim V

“…The human sinoatrial node (SAN) efficiently maintains heart rhythm even under adverse conditions. However, the specific mechanisms involved in the human SAN's…”
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Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node by Li, Ning, Kalyanasundaram, Anuradha, Hansen, Brian J., Artiga, Esthela J., Sharma, Roshan, Abudulwahed, Suhaib H., Helfrich, Katelynn M., Rozenberg, Galina, Wu, Pei-Jung, Zakharkin, Stanislav, Gyorke, Sandor, Janssen, Paul ML, Whitson, Bryan A., Mokadam, Nahush A., Biesiadecki, Brandon J., Accornero, Federica, Hummel, John D., Mohler, Peter J., Dobrzynski, Halina, Zhao, Jichao, Fedorov, Vadim V.

“…Mechanisms for human sinoatrial node (SAN) dysfunction are poorly understood and whether human SAN excitability requires voltage-gated sodium channels (Nav)…”
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Delayed bipolar voltage changes in the left atrium after vein of Marshall ethanol infusion by Okabe, Toshimasa, Bhuta, Sapan, Afzal, Muhammad R., Savona, Salvatore J., Kalbfleisch, Steven J., Houmsse, Mahmoud, Augostini, Ralph S., Daoud, Emile G., Hummel, John D.

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Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node by Li, Ning, Artiga, Esthela, Kalyanasundaram, Anuradha, Hansen, Brian J., Webb, Amy, Pietrzak, Maciej, Biesiadecki, Brandon, Whitson, Bryan, Mokadam, Nahush A., Janssen, Paul M. L., Hummel, John D., Mohler, Peter J., Dobrzynski, Halina, Fedorov, Vadim V.

“…Heart failure (HF) is frequently accompanied with the sinoatrial node (SAN) dysfunction, which causes tachy-brady arrhythmias and increased mortality. MicroRNA…”
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Identification of Repetitive Activation Patterns Using Novel Computational Analysis of Multielectrode Recordings During Atrial Fibrillation and Flutter in Humans by Daoud, Emile G., MD, Zeidan, Ziad, MD, Hummel, John D., MD, Weiss, Raul, MD, Houmsse, Mahmoud, MD, Augostini, Ralph, MD, Kalbfleisch, Steven J., MD

“…Abstract Objectives The purpose of this study was to assess computational analysis of 64-electrode basket catheter (BC) recordings of atrial fibrillation (AF)…”
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Unmasking Arrhythmogenic Hubs of Reentry Driving Persistent Atrial Fibrillation for Patient-Specific Treatment by Hansen, Brian J, Zhao, Jichao, Helfrich, Katelynn M, Li, Ning, Iancau, Alexander, Zolotarev, Alexander M, Zakharkin, Stanislav O, Kalyanasundaram, Anuradha, Subr, Megan, Dastagir, Nawshin, Sharma, Roshan, Artiga, Esthela J, Salgia, Nicholas, Houmsse, Mustafa M, Kahaly, Omar, Janssen, Paul M L, Mohler, Peter J, Mokadam, Nahush A, Whitson, Bryan A, Afzal, Muhammad R, Simonetti, Orlando P, Hummel, John D, Fedorov, Vadim V

“…Background Atrial fibrillation (AF) driver mechanisms are obscured to clinical multielectrode mapping approaches that provide partial, surface-only…”
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Rotor Ablation by Hummel, John D., MD

“…The mechanisms hypothesized to be responsible for the onset and maintenance of atrial fibrillation (AF) include pulmonary vein and extrapulmonary vein…”
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Real-World Assessment of Acute Left Ventricular Lead Implant Success and Complication Rates: Results from the Attain Success Clinical Trial by HUMMEL, JOHN D., COPPESS, MARK A., OSBORN, JEFFREY S., YEE, RAYMOND, FUNG, JEFFREY W.H., AUGOSTINI, RALPH, LI, SHELBY, HINE, DOUGLAS, SINGH, JAGMEET P.

“…Background Left ventricular lead (LVL) implant success rates have historically ranged between 70.5% and 95.5%. To date, there are few large studies that…”
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A long RP supraventricular tachycardia: What is the mechanism? by Okabe, Toshimasa, MD, Hummel, John D., MD, FHRS, Kalbfleisch, Steven J., MD, FHRS

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Extreme Obesity is Associated with Low Success Rate of Atrial Fibrillation Catheter Ablation by Okabe, Toshimasa, Buck, Benjamin, A Hayes, Samuel, T Harfi, Thura, R Afzal, Muhammad, Tyler, Jaret, Houmsse, Mahmoud, J Kalbfleisch, Steven, Weiss, Raul, D Hummel, John, S Augostini, Ralph, G Daoud, Emile

“…Catheter ablation (CA) is an established treatment for patients with symptomatic atrial fibrillation (AF). The purpose of this study was to evaluate the safety…”
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QTc compared to JTc for monitoring drug-induced repolarization changes in the setting of ventricular pacing by Tsai, Shane F., MD, Houmsse, Mahmoud, MD, FHRS, Dakhil, Barrah, MD, Augostini, Ralph, MD, FHRS, Hummel, John D., MD, FHRS, Kalbfleisch, Steven J., MD, FHRS, Liu, Zhengou, MD, PhD, Love, Charles, MD, FHRS, Rhodes, Troy, MD, PhD, Tyler, Jaret, MD, Weiss, Raul, MD, FHRS, Hamam, Ismail, MD, Winner, Marshall, MD, Daoud, Emile G., MD, FHRS

“…Background QT prolongation is a risk factor for proarrhythmia when beginning antiarrhythmic drug therapy (AAD). However, there are no data regarding monitoring…”
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Impact of International Normalized Ratio and Activated Clotting Time on Unfractionated Heparin Dosing During Ablation of Atrial Fibrillation by Hamam, Ismail, Daoud, Emile G, Zhang, Jianying, Kalbfleisch, Steven J, Augostini, Ralph, Winner, Marshall, Tsai, Shane, Rhodes, Troy E, Houmsse, Mahmoud, Liu, Zhenguo, Love, Charles J, Tyler, Jaret, Sachdev, Molly, Weiss, Raul, Hummel, John D

“…BACKGROUND—For ablation of atrial fibrillation, it is unclear how baseline international normalized ratio (INR) affects the dosing of unfractionated heparin…”
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Three-dimensional functional anatomy of the human sinoatrial node for epicardial and endocardial mapping and ablation by Kalyanasundaram, Anuradha, Li, Ning, Augostini, Ralph S., Weiss, Raul, Hummel, John D., Fedorov, Vadim V.

“…The sinoatrial node (SAN) is the primary pacemaker of the human heart. It is a single, elongated, 3-dimensional (3D) intramural fibrotic structure located at…”
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T-wave oversensing from postural changes: A rare cause of inappropriate shock from a subcutaneous defibrillator by Afzal, Muhammad R., Badin, Auroa, Weiss, Raul, Augostini, Ralph, Hummel, John D.

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Incidence of false-positive transmissions during remote rhythm monitoring with implantable loop recorders by Afzal, Muhammad R., Mease, Julie, Koppert, Tanner, Okabe, Toshimasa, Tyler, Jaret, Houmsse, Mahmoud, Augostini, Ralph S., Weiss, Raul, Hummel, John D., Kalbfleisch, Steven J., Daoud, Emile G.

“…Implantable loop recorder (ILR) is preferred strategy for prolonged rhythm monitoring. The purpose of this study was to report the incidence and causes of…”
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Leadless left ventricular stimulation with WiSE-CRT System – Initial experience and results from phase I of SOLVE-CRT Study (nonrandomized, roll-in phase) by Okabe, Toshimasa, Hummel, John D., Bank, Alan J., Niazi, Imran K., McGrew, Frank A., Kindsvater, Steven, Oza, Saumil R., Scherschel, John A., Walsh, Mary Norine, Singh, Jagmeet P.

“…Left ventricular (LV) endocardial pacing is a promising method to deliver cardiac resynchronization therapy (CRT). WiSE-CRT is a wireless LV endocardial pacing…”
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