Search Results - "Humble, M C"

Arsenic Enhancement of Skin Neoplasia by Chronic Stimulation of Growth Factors by Germolec, Dori R., Spalding, Judson, Yu, Hsin-Su, Chen, G.S., Simeonova, Petia P., Humble, Michael C., Bruccoleri, Alessandra, Boorman, Gary A., Foley, Julie F., Yoshida, Takahiko, Luster, Michael I.

“…Although numerous epidemiological studies have shown that inorganic arsenicals cause skin cancers and hyperkeratoses in humans, there are currently no…”
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Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review by HUMBLE, Michael C, TREMPUS, Carol S, SPALDING, Judson W, CANNON, Ronald E, TENNANT, Raymond W

“…The genetically initiated Tg.AC transgenic mouse carries a transgene consisting of an oncogenic v-Ha-ras coding region flanked 5' by a mouse zeta-globin…”
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Radial Transformation-Associated Recombination Cloning from the Mouse Genome: Isolation of Tg.AC Transgene with Flanking DNAs by Humble, Michael C., Kouprina, Natalya, Noskov, Vladimir N., Graves, Joan, Garner, Ed, Tennant, Raymond W., Resnick, Michael A., Larionov, Vladimir, Cannon, Ronald E.

“…Transformation-associated recombination (TAR) cloning allows entire genes and large chromosomal regions to be specifically, accurately, and quickly isolated…”
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Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice by Cannon, Ronald E., Spalding, Judson W., Trempus, Carol S., Szczesniak, Carl J., Virgil, Kelly M., Humble, Michael C., Tennant, Raymond W.

“…The Tg.AC transgenic mouse, which harbors an activated v‐Ha‐ras coding region that is fused to an embryonic ζ globin transcriptional control region and a 3′…”
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Induction of transgene expression in Tg.AC (v-Ha-ras) transgenic mice concomitant with DNA hypomethylation by Cannon, Ronald E., Spalding, Judson W., Virgil, Kelly M., Faircloth, Randall S., Humble, Michael C., Lacks, Gregory D., Tennant, Raymond W.

“…Tg.AC transgenic mice have a transgene composed of a ζ‐globin transcriptional control region, a v‐Ha‐ras coding region, and a simian virus 40 3′…”
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TGF alpha is dispensable for skin tumorigenesis in Tg.AC mice by Humble, M C, Szczesniak, C J, Luetteke, N C, Spalding, J W, Cannon, R E, Hansen, L A, Lee, D C, Tennant, R W

“…Alterations in growth factor signaling pathways frequently accompany the development and maintenance of epithelial neoplasia. Transforming growth factor alpha…”
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Clearing the Air: A Retrospective Observational Study of Rainfall and Pollen Count Data in Oklahoma City, OK by Humble, Brandon C., MD, Metz, Gregory M., MD

“…Results Interpreting the Pearson's correlation coefficient, in 2014 the data shows a large strength of association with R=0.58…”
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