The use of CytoSorb® in a prasugrel‐loaded patient undergoing emergent coronary artery bypass graft surgery

Patients with acute coronary syndrome (ACS), failed percutaneous coronary intervention (PCI) and with an indication for emergent coronary artery bypass graft surgery (CABG) are at an increased risk of perioperative bleeding. Integration of the CytoSorb® (CS) adsorber into the cardiopulmonary bypass...

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Bibliographic Details
Published in:	Clinical case reports Vol. 11; no. 3; pp. e6990 - n/a
Main Authors:	Moresco, Erich, Dejaco, Hannes, Humbert, Volker, Thoma, Matthias
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01-03-2023 John Wiley and Sons Inc Wiley
Subjects:	Acute coronary syndromes Aspirin Blood Blood platelets Cardiovascular disease Case Report Case reports Conflicts of interest Consent coronary artery bypass graft surgery Coronary vessels CytoSorb Electrocardiography Emergency medical care Heart surgery Medical imaging Metabolites Patients perioperative bleeding prasugrel, multiplate, platelet inhibition coronary artery bypass graft surgery prasugrel, multiplate, platelet inhibition perioperative bleeding CytoSorb
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Summary:	Patients with acute coronary syndrome (ACS), failed percutaneous coronary intervention (PCI) and with an indication for emergent coronary artery bypass graft surgery (CABG) are at an increased risk of perioperative bleeding. Integration of the CytoSorb® (CS) adsorber into the cardiopulmonary bypass appears to bind prasugrel and minimize the risk of perioperative bleeding. Intraoperative use of CytoSorb hemoadsorption therapy in prasugrel‐loaded patients undergoing emergency cardiac surgery might be an effective option to reduce the risk of bleeding complications. Further investigations, however, are needed for a better understanding of the precise role of the adsorber in this setting.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Report-1
ISSN:	2050-0904 2050-0904
DOI:	10.1002/ccr3.6990