Search Results - "Hum, D.W."

Drug repurposing screen identifies novel small molecule compounds with potent antifibrotic properties by Belanger, C, Foucart, C, Negro, E, Dubernet, M, Hum, D.W, Staels, B, Walczak, R

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The Identification of Novel Small Molecule Compounds with Potent Anti-Fibrotic Properties by Phenotypic Screening of Primary Human Stellate Cells by Belanger, C, Dubernet, M, Negro, E, Darteil, R, Hum, D.W, Staels, B, Walczak, R

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RORgt Inhibition in the Liver Prevents Hepatic Fibrosis Progression, a Proof of Concept Study with a Potent, First in Class, Hepatocentric RORgt Inverse Agonist by Majd, Z, Delhomel, J.-F, Delataille, P, Delbaere, I, Le Parquier, M, Hum, D.W, Staels, B, Walczak, R

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O78 Le GFT505, premier co-agoniste PPAR α/δ, a une double action favorable sur les paramètres lipidiques et glucidiques chez les sujets pré-diabétiques by Cariou, B, Hanf, R, Bruckert, E, Darteil, R, Hum, D.W, Staels, B

“…Introduction Le GFT505 est un nouveau médicament candidat dans le traitement des maladies métaboliques, qui agit en activant les récepteurs nucléaires PPARα et…”
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SAT-345 - Drug repurposing screen identifies novel small molecule compounds with potent antifibrotic properties by Belanger, C., Foucart, C., Negro, E., Dubernet, M., Hum, D.W., Staels, B., Walczak, R.

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SAT-418 - The Identification of Novel Small Molecule Compounds with Potent Anti-Fibrotic Properties by Phenotypic Screening of Primary Human Stellate Cells by Belanger, C., Dubernet, M., Negro, E., Darteil, R., Hum, D.W., Staels, B., Walczak, R.

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FRI-253 - RORgt Inhibition in the Liver Prevents Hepatic Fibrosis Progression, a Proof of Concept Study with a Potent, First in Class, Hepatocentric RORgt Inverse Agonist by Majd, Z., Delhomel, J.-F., Delataille, P., Delbaere, I., Le Parquier, M., Hum, D.W., Staels, B., Walczak, R.

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Levels of plasma C19 steroids and 5 alpha-reduced C19 steroid glucuronides in primates, rodents, and domestic animals by Guillemette, C, Hum, D.W, Belanger, A

“…In this study, a comparison of circulating levels of androsterone glucuronide and androstane-3 alpha, 17 beta-diol glucuronide in the male and female of…”
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Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency by FARDELLA, C. E, HUM, D. W, RODRIGUEZ, H, ZHANG, G, BARRY, F. L, ILICKI, A, BLOCH, C. A, MILLER, W. L

“…Cytochrome P450c11AS (aldosterone synthase) has 11 beta-hydroxylase, 18-hydroxylase, and 18-oxidase activities and is expressed solely in the adrenal zona…”
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4.P.304 HDL (high density lipoprotein) and LDL (low density lipoprotein) receptors regulation in human adrenal cortex by Martin, G., Pilon, A., Albert, C., Vallè, M., Hum, D.W., Fruchart, J.C., Auwerx, J., Clavey, V., Staels, B.

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A pseudogene on the X chromosome for the human trifunctional enzyme MTHFD (methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase) by Italiano, C, John, S W, Hum, D W, MacKenzie, R E, Rozen, R

“…The human trifunctional folate-dependent protein MTHFD has been mapped to chromosome 14q24 and to the X chromosome was identified by screening an…”
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3P-0818 GFT14, a novel compound with hypolipidemic and neuroprotective properties by Millatt, L., Darteil, R., Bertrand, K., Verwaerde, P., Hum, D.W., Raspe, E., Poulain, P., Majd, Z., Helleboid, S., Bouey, E., Bordet, R., Fruchart, J., Staels, B., Fruchart, J.-C.

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2P-0529 A novel family of compounds with beneficial effects in mouse models of dyslipidemia and ischemic stroke by Millatt, L., Bertrand, K., Darteil, R., Verwaerde, P., Hum, D.W., Provost, N., Poulain, P., Majd, Z., Helleboid, S., Delhomel, J.-F., Bordet, R., Fruchart, J., Staels, B., Fruchart, J.-C.

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