Search Results - "Hultman, Karin"

The APOE ε4/ε4 Genotype Potentiates Vascular Fibrin(Ogen) Deposition in Amyloid-Laden Vessels in the Brains of Alzheimer's Disease Patients by Hultman, Karin, Strickland, Sidney, Norris, Erin H

“…Evidence indicates a critical role for cerebrovascular dysfunction in Alzheimer's disease (AD) pathophysiology. We have shown that fibrin(ogen), the principal…”
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Challenging anthropocentric analysis of visual data: a relational materialist methodological approach to educational research by Hultman, Karin, Lenz Taguchi, Hillevi

“…The purpose of this paper is to challenge the habitual anthropocentric gaze we use when analysing educational data, which takes human beings as the starting…”
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GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand by Yang, Linda, Chang, Chih-Chuan, Sun, Zhe, Madsen, Dennis, Zhu, Haisun, Padkjær, Søren B, Wu, Xiaoai, Huang, Tao, Hultman, Karin, Paulsen, Sarah J, Wang, Jishu, Bugge, Anne, Frantzen, Jane Boesen, Nørgaard, Per, Jeppesen, Jacob Fuglsbjerg, Yang, Zhiru, Secher, Anna, Chen, Haibin, Li, Xun, John, Linu Mary, Shan, Bing, He, Zhenhua, Gao, Xiang, Su, Jing, Hansen, Kristian T, Yang, Wei, Jørgensen, Sebastian Beck

“…GDF15 has potent anti-obesity effects, but its receptor was unknown. GFRAL has now been identified as the receptor that mediates GDF15's effects via central…”
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GDF15 acts synergistically with liraglutide but is not necessary for the weight loss induced by bariatric surgery in mice by Frikke-Schmidt, Henriette, Hultman, Karin, Galaske, Joseph W., Jørgensen, Sebastian B., Myers, Martin G., Seeley, Randy J.

“…Analogues of GDF15 (Growth Differentiation Factor 15) are promising new anti-obesity therapies as pharmacological treatment with GDF15 results in dramatic…”
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ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis by Bengtsson, Eva, Hultman, Karin, Dunér, Pontus, Asciutto, Giuseppe, Almgren, Peter, Orho-Melander, Marju, Melander, Olle, Nilsson, Jan, Hultgårdh-Nilsson, Anna, Gonçalves, Isabel

“…Several large-scale genome-wide association studies have identified single-nucleotide polymorphisms in the genomic region of A Disintegrin And…”
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Expression of plasminogen activator inhibitor-1 and protease nexin-1 in human astrocytes: Response to injury-related factors by Hultman, Karin, Blomstrand, Fredrik, Nilsson, Michael, Wilhelmsson, Ulrika, Malmgren, Kristina, Pekny, Milos, Kousted, Tina, Jern, Christina, Tjärnlund-Wolf, Anna

“…Astrocytes play a diverse role in central nervous system (CNS) injury. Production of the serine protease inhibitors (serpins) plasminogen activator inhibitor‐1…”
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Maternal taurine supplementation in the late pregnant rat stimulates postnatal growth and induces obesity and insulin resistance in adult offspring by Hultman, Karin, Alexanderson, Camilla, Mannerås, Louise, Sandberg, Mats, Holmäng, Agneta, Jansson, Thomas

“…An adequate supply of taurine during fetal life is important for normal beta-cell development and insulin action. An altered availability of taurine may…”
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Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells by Olsson, Martina, Hultman, Karin, Dunoyer-Geindre, Sylvie, Curtis, Maurice A., Faull, Richard L. M., Kruithof, Egbert K. O., Jern, Christina

“…The serine protease tissue-type plasminogen activator (t-PA) is involved in both vital physiological brain processes, such as synaptic plasticity, and…”
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Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes by Tjärnlund-Wolf, Anna, Hultman, Karin, Blomstrand, Fredrik, Nilsson, Michael, Medcalf, Robert L., Jern, Christina

“…In recent years, the role and physiological regulation of the serine protease tissue-type plasminogen activator (t-PA) and its inhibitors, including…”
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The APOE epsilon 4/ epsilon 4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients by Hultman, Karin, Strickland, Sidney, Norris, Erin H

“…Evidence indicates a critical role for cerebrovascular dysfunction in Alzheimer's disease (AD) pathophysiology. We have shown that fibrin(ogen), the principal…”
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CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques by Bengtsson, Eva, Hultman, Karin, Edsfeldt, Andreas, Persson, Ana, Nitulescu, Mihaela, Nilsson, Jan, Gonçalves, Isabel, Björkbacka, Harry

“…Macrophages are a functionally heterogeneous group of immune cells abundant in atherosclerotic plaques. Macrophages expressing CD163 are associated with…”
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The central fibroblast growth factor receptor/beta klotho system: Comprehensive mapping in Mus musculus and comparisons to nonhuman primate and human samples using an automated in situ hybridization platform by Hultman, Karin, Scarlett, Jarrad M., Baquero, Arian F., Cornea, Anda, Zhang, Yu, Salinas, Casper B. G., Brown, Jenny, Morton, Gregory J., Whalen, Erin J., Grove, Kevin L., Koegler, Frank H., Schwartz, Michael W., Mercer, Aaron J.

“…Central activation of fibroblast growth factor (FGF) receptors regulates peripheral glucose homeostasis and reduces food intake in preclinical models of…”
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Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques by Hultman, Karin, Edsfeldt, Andreas, Björkbacka, Harry, Dunér, Pontus, Sundius, Lena, Nitulescu, Mihaela, Persson, Ana, Boyle, Joseph J, Nilsson, Jan, Hultgårdh-Nilsson, Anna, Bengtsson, Eva, Gonçalves, Isabel

“…BACKGROUND AND PURPOSE—Extracellular matrix proteins are important in atherosclerotic disease by influencing plaque stability and cellular behavior but also by…”
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IL-22 affects smooth muscle cell phenotype and plaque formation in apolipoprotein E knockout mice by Rattik, Sara, Hultman, Karin, Rauch, Uwe, Söderberg, Ingrid, Sundius, Lena, Ljungcrantz, Irena, Hultgårdh-Nilsson, Anna, Wigren, Maria, Björkbacka, Harry, Fredrikson, Gunilla Nordin, Nilsson, Jan

“…Abstract Objective IL-22 is a recently discovered cytokine that belongs to the family of IL-10 related cytokines. It is produced by activated T-cells and…”
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The APOE ɛ4/ɛ4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients by Hultman, Karin, Strickland, Sidney, Norris, Erin H

“…Evidence indicates a critical role for cerebrovascular dysfunction in Alzheimer's disease (AD) pathophysiology. We have shown that fibrin(ogen), the principal…”
Get full text

The APOE [epsilon]4/[epsilon]4 genotype potentiates vascular fibrin(ogen) deposition in amyloid-laden vessels in the brains of Alzheimer's disease patients by Hultman, Karin, Strickland, Sidney, Norris, Erin H

“…Evidence indicates a critical role for cerebrovascular dysfunction in Alzheimer's disease (AD) pathophysiology. We have shown that fibrin(ogen), the principal…”
Get full text

The central fibroblast growth factor receptor/beta klotho system: comprehensive mapping in mus musculus and comparisons to non-human primate and human samples using an automated in situ hybridization platform by Hultman, Karin, Scarlett, Jarrad M., Baquero, Arian F., Cornea, Anda, Zhang, Yu, Salinas, Casper B.G., Brown, Jenny, Morton, Gregory J., Whalen, Erin J., Grove, Kevin L., Koegler, Frank H., Schwartz, Michael W., Mercer, Aaron J.

“…Central activation of fibroblast growth factor (FGF) receptors regulates peripheral glucose homeostasis and reduces food intake in preclinical models of…”
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A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation? by Rakipovski, Günaj, Rolin, Bidda, Barascuk, Natasha, Lund, Heidi Engslev, Bjørn Bonde, Mathilde Frederikke, Djordjevic, Djordje, Wulff-Larsen, Pernille Gry, Petersen, Maj, Kirk, Rikke Kaae, Hultman, Karin, Manfe, Valentina, Blume, Niels, Zahn, Stefan, Lengquist, Mariette, Maegdefessel, Lars, Hovingh, G. Kees, Conde-Knape, Karin, Hedin, Ulf, Matic, Ljubica, Nyberg, Michael

“…Clinical interventions targeting nonlipid risk factors are needed given the high residual risk of atherothrombotic events despite effective control of…”
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High levels of cathepsin D and cystatin B are associated with increased risk of coronary events by Gonçalves, Isabel, Hultman, Karin, Dunér, Pontus, Edsfeldt, Andreas, Hedblad, Bo, Fredrikson, Gunilla Nordin, Björkbacka, Harry, Nilsson, Jan, Bengtsson, Eva

“…ObjectiveThe majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by…”
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Decreased levels of stem cell factor in subjects with incident coronary events by Wigren, M., Rattik, S., Hultman, K., Björkbacka, H., Nordin‐Fredrikson, G., Bengtsson, E., Hedblad, B., Siegbahn, A., Gonçalves, I., Nilsson, J.

“…Background It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in…”
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