Search Results - "Hultgren, Kevin"

Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity by Kang, Seounghun, Mansurov, Aslan, Kurtanich, Trevin, Chun, Hye Rin, Slezak, Anna J, Volpatti, Lisa R, Chang, Kevin, Wang, Thomas, Alpar, Aaron T, Refvik, Kirsten C, Hansen, O Isabella, Borjas, Gustavo J, Shim, Ha-Na, Hultgren, Kevin T, Gomes, Suzana, Solanki, Ani, Ishihara, Jun, Swartz, Melody A, Hubbell, Jeffrey A

“…Cancer immunotherapy is moving toward combination regimens with agents of complementary mechanisms of action to achieve more frequent and robust efficacy…”
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Injectable butyrate-prodrug micelles induce long-acting immune modulation and prevent autoimmune arthritis in mice by Cao, Shijie, Budina, Erica, Wang, Ruyi, Sabados, Matthew, Mukherjee, Anish, Solanki, Ani, Nguyen, Mindy, Hultgren, Kevin, Dhar, Arjun, Hubbell, Jeffrey A.

“…Short chain fatty acid (SCFAs), such as butyrate, have shown promising therapeutic potential due to their immunomodulatory effects, particularly in maintaining…”
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A serine-conjugated butyrate prodrug with high oral bioavailability suppresses autoimmune arthritis and neuroinflammation in mice by Cao, Shijie, Budina, Erica, Raczy, Michal M., Solanki, Ani, Nguyen, Mindy, Beckman, Taryn N., Reda, Joseph W., Hultgren, Kevin, Ang, Phillip S., Slezak, Anna J., Hesser, Lauren A., Alpar, Aaron T., Refvik, Kirsten C., Shores, Lucas S., Pillai, Ishita, Wallace, Rachel P., Dhar, Arjun, Watkins, Elyse A., Hubbell, Jeffrey A.

“…Butyrate—a metabolite produced by commensal bacteria—has been extensively studied for its immunomodulatory effects on immune cells, including regulatory T…”
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