Search Results - "Hulten, MA"

Crossing over analysis at pachytene in man by Barlow, A L, Hultén, M A

“…The distribution of anti-MLH1 (MutL homologue 1) antibody labelling was studied in human prophase meiocytes. A labelling pattern consisting of distinct foci,…”
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Childhood cancer and parental use of tobacco: deaths from 1971 to 1976 by SORAHAN, T, PRIOR, P, LANCASHIRE, R. J, FAUX, S. P, HULTEN, M. A, PECK, I. M, STEWART, A. M

“…Parental smoking data have been reabstracted from the interview records of the Oxford Survey of Childhood Cancers (deaths from 1971 to 1976). Reported smoking…”
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Childhood cancer and parental use of tobacco: deaths from 1953 to 1955 by SORAHAN, T, LANCASHIRE, R. J, HULTEN, M, PECK, I, STEWART, A. M

“…Parental smoking data have been abstracted from the interview records of the case-control study that first indicated that pregnancy radiographs are a cause of…”
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Rapid and simple prenatal diagnosis of common chromosome disorders: advantages and disadvantages of the molecular methods FISH and QF-PCR by Hulten, MA, Dhanjal, S, Pertl, B

“…Molecular techniques have been developed for prenatal diagnosis of the most common chromosome disorders (trisomies 21, 13, 18 and sex chromosome aneuploidies)…”
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On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model by Hultén, Maj A, Patel, Suketu, Jonasson, Jon, Iwarsson, Erik

“…We have recently documented that trisomy 21 mosaicism is common in human foetal ovaries. On the basis of this observation we propose that the maternal age…”
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Patterns of Meiotic Recombination in Human Fetal Oocytes by Tease, Charles, Hartshorne, Geraldine M., Hultén, Maj A.

“…Abnormal patterns of meiotic recombination (i.e., crossing-over) are believed to increase the risk of chromosome nondisjunction in human oocytes. To date,…”
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Inter-sex variation in synaptonemal complex lengths largely determine the different recombination rates in male and female germ cells by Tease, C, Hultén, M A

“…Meiotic chromosomes in human oocytes are packaged differently than in spermatocytes at the pachytene stage of meiosis I, when crossing-over takes place. Thus…”
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Trisomy 21 mosaicism: we may all have a touch of Down syndrome by Hultén, M A, Jonasson, J, Iwarsson, E, Uppal, P, Vorsanova, S G, Yurov, Y B, Iourov, I Y

“…Ever increasing sophistication in the application of new analytical technology has revealed that our genomes are much more fluid than was contemplated only a…”
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Disomy 21 in spermatozoa and the paternal origin of trisomy 21 Down syndrome by Iwarsson, Erik, Kvist, Ulrik, Hultén, Maj A

“…Trisomy 21 Down syndrome is the most common genetic cause for congenital malformations and intellectual disability. It is well known that in the outstanding…”
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Germinal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About? by Hulten, Maj, Jonasson, Jon, Nordgren, Ann, Iwarsson, Erik

“…It is well known that varying degrees of mosaicism for Trisomy 21, primarily a combination of normal and Trisomy 21 cells within individual tissues, may exist…”
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On the origin of crossover interference: A chromosome oscillatory movement (COM) model by Hulten, MA

“…It is now nearly a century since it was first discovered that crossovers between homologous parental chromosomes, originating at the Prophase stage of Meiosis…”
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Comment on "Origin of trisomy: no evidence to support the ovarian mosaicism theory" by Hulten, Maj Anita, Jonasson, Jon, Westgren, Magnus, Jonsson, Anna Maria, Papadogiannakis, Nikos, Iwarsson, Erik

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On the origin of trisomy 21 Down syndrome by Hultén, Maj A, Patel, Suketu D, Tankimanova, Maira, Westgren, Magnus, Papadogiannakis, Nikos, Jonsson, Anna Maria, Iwarsson, Erik

“…Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability. It is well known…”
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Distribution of the Rad51 recombinase in human and mouse spermatocytes by Barlow, Andrew L., Benson, Fiona E., West, Stephen C., Hultén, Maj A.

“…In vitro, the human Rad51 protein (hRad51) promotes homologous pairing and strand exchange reactions suggestive of a key role in genetic recombination. To…”
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On the paternal origin of trisomy 21 Down syndrome by Hultén, Maj A, Patel, Suketu D, Westgren, Magnus, Papadogiannakis, Nikos, Jonsson, Anna Maria, Jonasson, Jon, Iwarsson, Erik

“…Down syndrome (DS), characterized by an extra free chromosome 21 is the most common genetic cause for congenital malformations and learning disability. It is…”
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O-8. Direct testing of meiotic recombination in the human female by Hulten, MA, Tease, C

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The initiation of homologous chromosome synapsis in mouse fetal oocytes is not directly driven by centromere and telomere clustering in the bouquet by Tankimanova, M, Hultén, M A, Tease, C

“…We investigated the behaviour of centromeres and distal telomeres during the initial phases of female meiosis in mice. In particular, we wished to determine…”
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Feature representation and signal classification in fluorescence in-situ hybridization image analysis by Lerner, B., Clocksin, W.F., Dhanjal, S., Hulten, M.A., Bishop, C.M.

“…Fast and accurate analysis of fluorescence in-situ hybridization images for signal counting will depend mainly upon two components: a classifier to…”
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Growth factors promote meiosis in mouse fetal ovaries in vitro by Lyrakou, S., Hultén, M.A., Hartshorne, G.M.

“…Mouse fetal ovaries were cultured to investigate germ cell development in the presence of a combination of the growth factors (GFs) stem cell factor,…”
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Meiotic Studies of a Human Male Carrier of the Common Translocation, t(11;22), Suggests Postzygotic Selection rather than Preferential 3:1 MI Segregation as the Cause of Liveborn Offspring with an Unbalanced Translocation by Armstrong, Susan J., Goldman, Alastair S.H., Speed, Robert M., Hultén, Maj A.

“…The t(11;22)(q23;q11) translocation is the only non-Robertsonian rearrangement for which there are a large number of unrelated families, apparently with the…”
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