Search Results - "Hult, Caitlin"

Dynamic balance of pro‐ and anti‐inflammatory signals controls disease and limits pathology by Cicchese, Joseph M., Evans, Stephanie, Hult, Caitlin, Joslyn, Louis R., Wessler, Timothy, Millar, Jess A., Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Kirschner, Denise E.

“…Immune responses to pathogens are complex and not well understood in many diseases, and this is especially true for infections by persistent pathogens. One…”
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Neutrophil Dynamics Affect Mycobacterium tuberculosis Granuloma Outcomes and Dissemination by Hult, Caitlin, Mattila, Joshua T, Gideon, Hannah P, Linderman, Jennifer J, Kirschner, Denise E

“…Neutrophil infiltration into tuberculous granulomas is often associated with higher bacteria loads and severe disease but the basis for this relationship is…”
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Transient crosslinking kinetics optimize gene cluster interactions by Walker, Benjamin, Taylor, Dane, Lawrimore, Josh, Hult, Caitlin, Adalsteinsson, David, Bloom, Kerry, Forest, M Gregory

“…Our understanding of how chromosomes structurally organize and dynamically interact has been revolutionized through the lens of long-chain polymer physics…”
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The Role of Dimensionality in Understanding Granuloma Formation by Marino, Simeone, Hult, Caitlin, Wolberg, Paul, Linderman, Jennifer J, Kirschner, Denise E

“…Within the first 2-3 months of a (Mtb) infection, 2-4 mm spherical structures called granulomas develop in the lungs of the infected hosts. These are the…”
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Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus by Hult, Caitlin, Adalsteinsson, David, Vasquez, Paula A, Lawrimore, Josh, Bennett, Maggie, York, Alyssa, Cook, Diana, Yeh, Elaine, Forest, Mark Gregory, Bloom, Kerry

“…Regions of highly repetitive DNA, such as those found in the nucleolus, show a self-organization that is marked by spatial segregation and frequent…”
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The power of weak, transient interactions across biology: A paradigm of emergent behavior by Vasquez, Paula A., Walker, Ben, Bloom, Kerry, Kolbin, Daniel, Caughman, Neall, Freeman, Ronit, Lysy, Martin, Hult, Caitlin, Newhall, Katherine A., Papanikolas, Micah, Edelmaier, Christopher, Forest, M. Gregory

“…A growing list of diverse biological systems and their equally diverse functionalities provides realizations of a paradigm of emergent behavior. In each of…”
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Entropy gives rise to topologically associating domains by Vasquez, Paula A, Hult, Caitlin, Adalsteinsson, David, Lawrimore, Josh, Forest, Mark G, Bloom, Kerry

“…We investigate chromosome organization within the nucleus using polymer models whose formulation is closely guided by experiments in live yeast cells. We…”
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Global sensitivity analysis of biological multiscale models by Renardy, Marissa, Hult, Caitlin, Evans, Stephanie, Linderman, Jennifer J., Kirschner, Denise E.

“…Mathematical models of biological systems need to both reflect and manage the inherent complexities of biological phenomena. Through their versatility and…”
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Polymer Modeling Reveals Interplay between Physical Properties of Chromosomal DNA and the Size and Distribution of Condensin-Based Chromatin Loops by Kolbin, Daniel, Walker, Benjamin L, Hult, Caitlin, Stanton, John Donoghue, Adalsteinsson, David, Forest, M Gregory, Bloom, Kerry

“…Transient DNA loops occur throughout the genome due to thermal fluctuations of DNA and the function of SMC complex proteins such as condensin and cohesin…”
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Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology by Cicchese, Joseph M., Evans, Stephanie, Hult, Caitlin, Joslyn, Louis R., Wessler, Timothy, Millar, Jess A., Marino, Simeone, Cilfone, Nicholas A., Mattila, Joshua T., Linderman, Jennifer J., Kirschner, Denise E.

“…Immune responses to pathogens are complex and not well understood in many diseases, and this is especially true for infections by persistent pathogens. One…”
Get full text

Global sensitivity analysis of biological multi-scale models by Renardy, Marissa, Hult, Caitlin, Evans, Stephanie, Linderman, Jennifer J, Kirschner, Denise E

“…Mathematical models of biological systems need to both reflect and manage the inherent complexities of biological phenomena. Through their versatility and…”
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Modeling Nucleosomal DNA in Living Yeast by Hult, Caitlin Suzanne

“…The genome in living yeast cells is a highly dynamic system where entropic interactions and nuclear confinement drive the formation of domains of high…”
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Transient crosslinking kinetics optimize gene cluster interactions by Walker, Benjamin, Taylor, Dane, Lawrimore, Josh, Hult, Caitlin, Adalsteinsson, David, Bloom, Kerry, Forest, M. Gregory

“…Our understanding of how chromosomes structurally organize and dynamically interact has been revolutionized through the lens of long-chain polymer physics…”
Get full text