Search Results - "Hulmes, Jeffrey"
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Changes in Biological Activity and Folding of Guanylate Cyclase-Activating Protein 1 as a Function of Calcium
Published in Biochemistry (Easton) (06-01-1998)“…Guanylate cyclase-activating protein 1 (GCAP1), a photoreceptor-specific Ca2+-binding protein, activates retinal guanylate cyclase 1 (GC1) during the recovery…”
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2
Cloning and Functional Expression of a Human Heparanase Gene
Published in Biochemical and biophysical research communications (22-07-1999)“…We have cloned a gene (HSE1) from a human placental cDNA library that encodes a novel protein exhibiting heparanase activity. The cDNA was identified through…”
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3
Structural Heterogeneity and Functional Domains of Murine Immunoglobulin G Fc Receptors
Published in Science (American Association for the Advancement of Science) (07-11-1986)“…Binding of antibodies to effector cells by way of receptors to their constant regions (Fc receptors) is central to the pathway that leads to clearance of…”
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4
Proximity Mapping of the Tet Repressor-Tetracycline-Fe2+ Complex by Hydrogen Peroxide Mediated Protein Cleavage
Published in Biochemistry (Easton) (10-01-1995)“…We demonstrate in a quantitative in vitro induction assay that tetracycline-Fe2+ is a more than 1000-fold stronger inducer of Tet repressor compared to…”
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5
Inhibition of Human Cytomegalovirus UL80 Protease by Specific Intramolecular Disulfide Bond Formation
Published in Biochemistry (Easton) (07-05-1996)“…A symmetrically substituted disulfide compound, CL13933, was identified as a potent inhibitor of human cytomegalovirus UL80 protease. Two types of inhibited…”
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6
Cellular Retinaldehyde-binding Protein Ligand Interactions
Published in The Journal of biological chemistry (14-08-1998)“…Cellular retinaldehyde-binding protein (CRALBP) carries 11-cis-retinal and/or 11-cis-retinol as endogenous ligands in the retinal pigment epithelium (RPE) and…”
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7
Purification to Homogeneity and Partial Characterization of Cytotoxic Lymphocyte Maturation Factor From Human B-Lymphoblastoid Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1990)“…A cytokine that can synergize with interleukin 2 to activate cytotoxic lymphocytes was purified to homogeneity. The protein, provisionally called cytotoxic…”
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Purification and sequencing of a rat intestinal 22 amino acid C-terminal CCK fragment
Published in Peptides (New York, N.Y. : 1980) (01-11-1984)“…Fractionation on Sephadex G50 gel of methanol extracts of rat intestine revealed two molecular forms of cholecystokinin (CCK) of about equal immunopotency: one…”
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9
Primary structure of equine pituitary prolactin
Published in International journal of peptide and protein research (01-06-1988)“…Equine prolactin was determined to be a single chain protein of 199 amino acid containing two tryptophan and six cysteine residues, as found in other mammalian…”
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10
Semi-Automated Sample Preparation for Plasma Proteomics
Published in Journal of Laboratory Automation (01-08-2004)“…The discovery of new biomarkers will be an essential step to enhance our ability to better diagnose and treat human disease. The proteomics research community…”
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Direct identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3'-kinase binding
Published in Biochemical journal (01-09-2001)“…Progress has been made in our understanding of the mechanism by which the binding of vascular endothelial growth factor (VEGF) to cognate receptors induces a…”
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12
cDNA Sequence Encoding the 16-kDa Proteolipid of Chromaffin Granules Implies Gene Duplication in the Evolution of H+-ATPases
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1988)“…Vacuolar H+-ATPases function in generating protonmotive force across the membranes of organelles connected with the vacuolar system of eukaryotic cells. This…”
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13
Direct identification of a major autophosphorylation site on vascular endothelial growth factor receptor Flt-1 that mediates phosphatidylinositol 3′-kinase binding
Published in Biochemical journal (01-09-2001)“…Progress has been made in our understanding of the mechanism by which the binding of vascular endothelial growth factor (VEGF) to cognate receptors induces a…”
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14
Cellular retinaldehyde-binding protein ligand interactions. Gln-210 and Lys-221 are in the retinoid binding pocket
Published in The Journal of biological chemistry (14-08-1998)“…Cellular retinaldehyde-binding protein (CRALBP) carries 11-cis-retinal and/or 11-cis-retinol as endogenous ligands in the retinal pigment epithelium (RPE) and…”
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15
Expression and analysis of the human cytomegalovirus UL80-encoded protease: identification of autoproteolytic sites
Published in Journal of Virology (01-01-1993)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural and functional characterization of recombinant human cellular retinaldehyde‐binding protein
Published in Protein science (01-03-1998)“…Cellular retinaldehyde‐binding protein (CRALBP) is abundant in the retinal pigment epithelium (RPE) and Miiller cells of the retina where it is thought to…”
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Molecular characterization of interleukin 12
Published in Archives of biochemistry and biophysics (01-04-1992)“…Interleukin 12 (IL-12), formerly known as cytotoxic lymphocyte maturation factor and natural killer cell stimulatory factor, is a cytokine secreted by a human…”
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18
Purification and partial amino acid sequence of a mu opioid receptor from rat brain
Published in The Journal of biological chemistry (15-12-1993)“…A rat brain opioid receptor protein was isolated by binding [epsilon-biotinyl-Lys32] beta-endorphin to membranes, solubilizing the receptor-ligand (R.L)…”
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19
Purification and characterization of glycosyl-phosphatidylinositol-specific phospholipase D
Published in The Journal of biological chemistry (15-10-1990)“…We have developed a simple immunoaffinity chromatography procedure for the purification of a glycosyl-phosphatidylinositol (GPI)-specific phospholipase D…”
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20
The use of fluorescamine as a detection reagent in protein microcharacterization
Published in Journal of biochemical and biophysical methods (01-02-1989)“…With recent advances in protein microchemistry, compatible methods for the preparation and quantitation of proteins and peptides are required. Fluorescamine, a…”
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