Search Results - "Hull, Robert A."

Soil Metals Analysis Using Laser-Induced Breakdown Spectroscopy (LIBS) by Essington, Michael E, Melnichenko, Galina V, Stewart, Melanie A, Hull, Robert A

“…Laser-induced breakdown spectroscopy (LIBS) is an elemental analysis technique that is based on the measurement of atomic emissions generated on a sample…”
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Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists by McDonald, Iain M, Austin, Carol, Buck, Ildiko M, Dunstone, David J, Gaffen, John, Griffin, Eric, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Linney, Ian D, Low, Caroline M. R, Patel, Dipa, Pether, Michael J, Raynor, Michelle, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Wright, Paul T, Xun, Wei

“…A 1,3,4-benzotriazepine was identified as a suitable lead in our effort toward obtaining a non-peptide parathyroid hormone-1 receptor (PTH1R) antagonist. A…”
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Optimization of 1,3,4-Benzotriazepine-Based CCK2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion by McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I. M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei

“…Starting from a novel, achiral 1,3,4-benzotriazepine-based CCK2 receptor antagonist, a process of optimization has afforded further compounds of this type that…”
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Adoption of coronary artery disease - Reporting and Data System (CAD-RADS™) and observed impact on medical therapy and systolic blood pressure control by Hull, Robert A., Berger, Jeremy M., Boster, Joshua M., Williams, Michael U., Sharp, Alec J., Fentanes, Emilio, Maroules, Christopher D., Cury, Ricardo C., Thomas, Dustin M.

“…CAD-RADS was developed to standardize communication of per-patient maximal stenosis on coronary CT angiography (CCTA) and provide treatment recommendations and…”
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Evaluation of Nitric Acid Extraction of Elements from Soils and Sediments in Two watersheds in East Tennessee by Huangfu, Yanchong, Essington, Michael E., Hawkins, Shawn A., Walker, Forbes R., Schwartz, John S., Layton, Alice C., Hull, Robert A.

“…Determining the total elemental concentrations of soils requires a total dissolution method, in which hydrofluoric acid (HF) is commonly used. However, this…”
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Right Ventricular Failure Following Patent Foramen Ovale Closure on Venovenous-Extracorporeal Membrane Oxygenation by Hull, Robert A., Hunninghake, John C., Walter, Robert J., Mason, Phillip E., Pickett, Christopher A., Bush, Kelvin N.V.

“…We present a patient with pulmonary arterial hypertension requiring venovenous-extracorporeal membrane oxygenation for acute respiratory distress syndrome…”
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Left atrial appendage morphology and risk of stroke following pulmonary vein isolation for drug-refractory atrial fibrillation in low CHA2DS2Vasc risk patients by Kelly, Faith R., Hull, Robert A., Arrey-Mbi, Takor B., Williams, Michael U., Lee, Joshua S., Slim, Ahmad M., Thomas, Dustin M.

“…Background Cardiac CT angiography (CCTA) has become an important adjunct in the structural assessment of the pulmonary veins (PV) prior to pulmonary vein…”
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Novel, Achiral 1,3,4-Benzotriazepine Analogues of 1,4-Benzodiazepine-Based CCK2 Antagonists That Display High Selectivity over CCK1 Receptors by McDonald, Iain M, Austin, Carol, Buck, Ildiko M, Dunstone, David J, Griffin, Eric, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Linney, Ian D, Low, Caroline M. R, Pether, Michael J, Spencer, John, Wright, Paul T, Adatia, Trushar, Bashall, Alan

“…A series of 1,3,4-benzotriazepine-based CCK2 antagonists have been devised by consideration of the structural features that govern CCK receptor affinity and…”
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Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK2) Antagonists by Buck, Ildiko M, Black, James W, Cooke, Tracey, Dunstone, David J, Gaffen, John D, Griffin, Eric P, Harper, Elaine A, Hull, Robert A. D, Kalindjian, S. Barret, Lilley, Elliot J, Linney, Ian D, Low, Caroline M. R, McDonald, Iain M, Pether, Michael J, Roberts, Sonia P, Shankley, Nigel P, Shaxted, Mark E, Steel, Katherine I. M, Sykes, David A, Tozer, Matthew J, Watt, Gillian F, Walker, Martin K, Wright, Laurence, Wright, Paul T

“…The systematic optimization of the structure of a novel 2,4,5-trisubstituted imidazole-based cholecystokinin-2 (CCK2) receptor antagonist afforded analogues…”
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Development of Peptide 3D Structure Mimetics:  Rational Design of Novel Peptoid Cholecystokinin Receptor Antagonists by Low, Caroline M. R, Black, James W, Broughton, Howard B, Buck, Ildiko M, Davies, Jonathan M. R, Dunstone, David J, Hull, Robert A. D, Kalindjian, S. Barret, McDonald, Iain M, Pether, Michael J, Shankley, Nigel P, Steel, Katherine I. M

“…The two hormones cholecystokinin and gastrin share the same C-terminal sequence of amino acids, namely Gly29-Trp30-Met31-Asp32-Phe33-NH2. Nevertheless, this…”
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Left atrial appendage morphology and risk of stroke following pulmonary vein isolation for drug-refractory atrial fibrillation in low CHA 2 DS 2 Vasc risk patients by Kelly, Faith R, Hull, Robert A, Arrey-Mbi, Takor B, Williams, Michael U, Lee, Joshua S, Slim, Ahmad M, Thomas, Dustin M

“…Cardiac CT angiography (CCTA) has become an important adjunct in the structural assessment of the pulmonary veins (PV) prior to pulmonary vein isolation (PVI)…”
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Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion by McDonald, Iain M, Black, James W, Buck, Ildiko M, Dunstone, David J, Griffin, Eric P, Harper, Elaine A, Hull, Robert A D, Kalindjian, S Barret, Lilley, Elliot J, Linney, Ian D, Pether, Michael J, Roberts, Sonia P, Shaxted, Mark E, Spencer, John, Steel, Katherine I M, Sykes, David A, Walker, Martin K, Watt, Gillian F, Wright, Laurence, Wright, Paul T, Xun, Wei

“…Starting from a novel, achiral 1,3,4-benzotriazepine-based CCK2 receptor antagonist, a process of optimization has afforded further compounds of this type that…”
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Optimization of 1,3,4-Benzotriazepine-Based CCK 2 Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion by McDonald, Iain M., Black, James W., Buck, Ildiko M., Dunstone, David J., Griffin, Eric P., Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Lilley, Elliot J., Linney, Ian D., Pether, Michael J., Roberts, Sonia P., Shaxted, Mark E., Spencer, John, Steel, Katherine I. M., Sykes, David A., Walker, Martin K., Watt, Gillian F., Wright, Laurence, Wright, Paul T., Xun, Wei

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Novel, achiral 1,3,4-benzotriazepine analogues of 1,4-benzodiazepine-based CCK(2) antagonists that display high selectivity over CCK(1) receptors by McDonald, Iain M, Austin, Carol, Buck, Ildiko M, Dunstone, David J, Griffin, Eric, Harper, Elaine A, Hull, Robert A D, Kalindjian, S Barret, Linney, Ian D, Low, Caroline M R, Pether, Michael J, Spencer, John, Wright, Paul T, Adatia, Trushar, Bashall, Alan

“…A series of 1,3,4-benzotriazepine-based CCK(2) antagonists have been devised by consideration of the structural features that govern CCK receptor affinity and…”
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Novel, Achiral 1,3,4-Benzotriazepine Analogues of 1,4-Benzodiazepine-Based CCK 2 Antagonists That Display High Selectivity over CCK 1 Receptors by McDonald, Iain M., Austin, Carol, Buck, Ildiko M., Dunstone, David J., Griffin, Eric, Harper, Elaine A., Hull, Robert A. D., Kalindjian, S. Barret, Linney, Ian D., Low, Caroline M. R., Pether, Michael J., Spencer, John, Wright, Paul T., Adatia, Trushar, Bashall, Alan

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Right Ventricular Failure Following Patent Foramen Ovale Closure on Venovenous-Extracorporeal Membrane Oxygenation by Hull, Robert A, Hunninghake, John C, Walter, Robert J, Mason, Phillip E, Pickett, Christopher A, Bush, Kelvin N V

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Inotropic polyazapentalene sulmazole analogues by Barraclough, P, Black, J W, Cambridge, D, Firmin, D, Gerskowitch, V P, Glen, R C, Giles, H, Gillam, J M, Hull, R A, Iyer, R

“…Aryl substituted 1H-imidazo[1,2-a]imidazole 8, imidazo[2,1-b]thiazole 9, 1,4-dihydroimidazo[4,5-d]imidazole 11, and 1(2),4-dihydroimidazo[4,5-c]pyrazoles 12-17…”
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Inotropic activities of imidazopyridines by Barraclough, P, Black, J W, Cambridge, D, Gerskowitch, V P, Hull, R A, Lyer, R, King, W R, Kneen, C O, Nobbs, M S, Shah, G P

“…A series of 2-substituted 1H-imidazo[4,5-b]pyridines and the isomeric 1H-imidazo[4,5-c]pyridine derivatives has been prepared and evaluated as inotropic…”
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Cardiotonic 'C' ring modified isomazole analogues by Barraclough, P, Black, J W, Cambridge, D, Demaine, D A, Gerskowitch, V P, Giles, H, Hill, A P, Hull, R A, Lyer, R, King, W R

“…Isomazole analogues which have achiral electron withdrawing substituents at the 4'-position and analogues with heterocyclic 'C' rings have been synthesized and…”
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