Search Results - "Hull, MA"

Cyclooxygenase-2: How good is it as a target for cancer chemoprevention? by Hull, Mark A.

“…There is now substantial evidence for a role for cyclooxygenase-2 (COX-2)-mediated prostaglandin (PG) signalling during carcinogenesis in a number of tissues…”
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The omega‐3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC‐26 colorectal cancer cell liver metastasis via inhibition of PGE2‐dependent cell motility by Hawcroft, G, Volpato, M, Marston, G, Ingram, N, Perry, SL, Cockbain, AJ, Race, AD, Munarini, A, Belluzzi, A, Loadman, PM, Coletta, PL, Hull, MA

“…BACKGROUND AND PURPOSE The omega‐3 polyunsaturated fatty acid (PUFA) eicosapentaenoic acid (EPA) has antineoplastic activity at early stages of colorectal…”
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Increasing Prescription of Opiates and Mortality in Patients With Inflammatory Bowel Diseases in England by Burr, Nicholas E., Smith, Chris, West, Robert, Hull, Mark A., Subramanian, Venkataraman

“…The prescription of opiate medications is increasing. Individuals with inflammatory bowel diseases (IBD) can develop serious complications from opiate use, but…”
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Increased Risk of Colorectal Cancer After Obesity Surgery by Derogar, Maryam, Hull, Mark A, Kant, Prashant, Östlund, Magdalena, Lu, Yunxia, Lagergren, Jesper

“…OBJECTIVE:The purpose was to determine whether obesity surgery is associated with a long-term increased risk of colorectal cancer. BACKGROUND:Long-term cancer…”
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Obesity surgery and risk of colorectal and other obesity-related cancers: An English population-based cohort study by Aravani, Ariadni, Downing, Amy, Thomas, James D., Lagergren, Jesper, Morris, Eva J.A., Hull, Mark A.

“…•The association between obesity surgery (OS) and cancer risk remains unclear.•Colorectal cancer (CRC) risk is increased in obese individuals.•No evidence of…”
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Colorectal Cancer Prognosis Following Obesity Surgery in a Population-Based Cohort Study by Tao, Wenjing, Konings, Peter, Hull, Mark A., Adami, Hans-Olov, Mattsson, Fredrik, Lagergren, Jesper

“…Background Obesity surgery involves mechanical and physiological changes of the gastrointestinal tract that might promote colorectal cancer progression. Thus,…”
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The omega‐3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC‐26 colorectal cancer cell liver metastasis via inhibition of PGE 2 ‐dependent cell motility by Hawcroft, G, Volpato, M, Marston, G, Ingram, N, Perry, SL, Cockbain, AJ, Race, AD, Munarini, A, Belluzzi, A, Loadman, PM, Coletta, PL, Hull, MA

“…BACKGROUND AND PURPOSE The omega‐3 polyunsaturated fatty acid (PUFA) eicosapentaenoic acid (EPA) has antineoplastic activity at early stages of colorectal…”
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Prostaglandin EP receptors: Targets for treatment and prevention of colorectal cancer? by Hull, Mark A, Ko, Stanley C W, Hawcroft, Gillian

“…The importance of the prostaglandin (PG) synthesis pathway, particularly the rate-limiting enzymatic step catalyzed by cyclooxygenase, to colorectal…”
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The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action by Smith, M.-L, Hawcroft, G, Hull, M.A

“…Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit proliferation and induce apoptosis in human colorectal cancer cells in vitro. It remains unclear whether…”
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Macrophage Migration Inhibitory Factor Promotes Intestinal Tumorigenesis by Wilson, Jonathan M., Coletta, P. Louise, Cuthbert, Richard J., Scott, Nigel, MacLennan, Kenneth, Hawcroft, Gillian, Leng, Lin, Lubetsky, Jodi B., Jin, Kai K., Lolis, Elias, Medina, Francisco, Brieva, Jose A., Poulsom, Richard, Markham, Alexander F., Bucala, Richard, Hull, Mark A.

“…Background & Aims: The cytokine macrophage migration inhibitory factor (MIF) is expressed throughout the human gastrointestinal tract. Recently, protumorigenic…”
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The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases by Fenwick, Stephen W., Toogood, Giles J., Lodge, J.Peter A., Hull, Mark A.

“…Background & Aims : Cyclooxygenase-2 (COX-2) is a potential target for chemotherapy of colorectal cancer (CRC). We tested the antineoplastic activity of the…”
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Differential CD74 (major histocompatibility complex Class II invariant chain) expression in mouse and human intestinal adenomas by Cuthbert, R.J, Wilson, J.M, Scott, N, Coletta, P.L, Hull, M.A

“…Abstract CD74 (major histocompatibility complex (MHC) Class II invariant chain) has recently been identified as the cell-surface receptor for the…”
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Localization of Cyclooxygenase-2 in Human Sporadic Colorectal Adenomas by Chapple, Keith S., Cartwright, Elizabeth J., Hawcroft, Gillian, Tisbury, Alison, Bonifer, Constanze, Scott, Nigel, Windsor, Alistair C.J., Guillou, Pierre J., Markham, Alexander F., Coletta, P. Louise, Hull, Mark A.

“…A putative target for the anti-colorectal cancer action of nonsteroidal anti-inflammatory drugs is the inducible isoform of cyclooxygenase (COX), COX-2. COX-2…”
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Effect of nonsteroidal anti-inflammatory drugs on β-catenin protein levels and catenin-related transcription in human colorectal cancer cells by GARDNER, S. H, HAWCROFT, G, HULL, M. A

“…Elevated beta-catenin levels in human colorectal cancer (CRC) cells lead to increased trans-activation of 'protumorigenic' beta-catenin/T-cell factor (TCF)…”
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Activity of the non-steroidal anti-inflammatory drug indomethacin against colorectal cancer by Hull, M.A, Gardner, S.H, Hawcroft, G

“…A substantial body of evidence from rodent colon carcinogenesis models, in vitro experiments with human colorectal cancer cells and limited clinical…”
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Nonprofits and C Corporations: Performance Comparison by Hull, Robert Martin

“…We extend the performance comparison study of nonprofits (NPs) and pass-throughs by examining large NPs and large C corporations (CCs). Unlike that study, we…”
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Indomethacin induces differential expression of β-catenin, γ-catenin and T-cell factor target genes in human colorectal cancer cells by Hawcroft, Gillian, D'Amico, Mark, Albanese, Chris, Markham, Alexander F., Pestell, Richard G., Hull, Mark A.

“…Indomethacin-induced G1 arrest and apoptosis of human colorectal cancer (CRC) cells is associated with a dose-dependent decrease in β-catenin protein levels…”
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Fulminant Crohn’s colitis after allogeneic stem cell transplantation by Sonwalkar, S A, James, R M, Ahmad, T, Zhang, L, Verbeke, C S, Barnard, D L, Jewell, D P, Hull, M A

“…We report a case of fulminant Crohn’s colitis that occurred following non-myeloablative allogeneic stem cell transplantation for Hodgkin’s lymphoma. Adoptive…”
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Two documents by Chin-Yee, Benjamin Hull, BSc MA

“…The author was struck by two documents in his grandfather's possession. The first, a photograph of his mother -- his great-grandmother. The photograph is not…”
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Lack of interleukin-4 receptor α chain-dependent signalling promotes azoxymethane-induced colorectal aberrant crypt focus formation in Balb/c mice by Ko, CWS, Cuthbert, RJ, Orsi, NM, Brooke, DA, Perry, SL, Markham, AF, Coletta, PL, Hull, MA

“…Interleukin (IL)-4 receptor (IL-4R) α chain-dependent signalling by IL-4 and IL-13 promotes tumour growth and metastasis in mouse models of colorectal cancer…”
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