Search Results - "Hull, Claire"

Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-Resistance to Azoles and Amphotericin B by HULL, Claire M, PARKER, Josie E, BADER, Oliver, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L

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Venous Thromboembolism and Marathon Athletes by Hull, Claire M, Harris, Julia A

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Two Clinical Isolates of Candida glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2 by HULL, Claire M, BADER, Oliver, PARKER, Josie E, WEIG, Michael, GROSS, Uwe, WARRILOW, Andrew G. S, KELLY, Diane E, KELLY, Steven L

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Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants by Arastoo, Mohammad, Mazanetz, Michael P, Miller, Sonya, Shiells, Helen, Hull, Claire, Robinson, Keith, Storey, John M. D, Harrington, Charles R, Wischik, Claude M

“…Methylthioninium chloride (MTC) is a standard treatment for methaemoglobinaemia. A preparation of reduced MTC has been reported to increase blood oxygen…”
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Venous Thromboembolism in Physically Active People: Considerations for Risk Assessment, Mainstream Awareness and Future Research by Hull, Claire M., Harris, Julia A.

“…The global healthcare burden of venous thromboembolism (VTE) and associated comorbidities (e.g. obesity, heart disease and cancer) is significant. Physical…”
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Clotrimazole as a potent agent for treating the oomycete fish pathogen Saprolegnia parasitica through inhibition of sterol 14α-demethylase (CYP51) by Warrilow, Andrew G S, Hull, Claire M, Rolley, Nicola J, Parker, Josie E, Nes, W David, Smith, Stephen N, Kelly, Diane E, Kelly, Steven L

“…A candidate CYP51 gene encoding sterol 14α-demethylase from the fish oomycete pathogen Saprolegnia parasitica (SpCYP51) was identified based on conserved CYP51…”
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Deep Vein Thrombosis and Pulmonary Embolism in a Mountain Guide: Awareness, Diagnostic Challenges, and Management Considerations at Altitude by Hull, Claire M., PhD, Rajendran, Dévan, DO, Fernandez Barnes, Arturo, DO

“…High intensity exercise is associated with several potentially thrombogenic risk factors, including dehydration and hemoconcentration, vascular trauma,…”
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Apolipoprotein E loss of function: Influence on murine brain markers of physiology and pathology by Buchanan, Heather, Hull, Claire, Cacho Barraza, Maria, Delibegovic, Mirela, Platt, Bettina

“…The canonical role of Apolipoprotein E (ApoE) is related to lipid and cholesterol metabolism, however, additional functions of this protein have not been fully…”
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S279 Point Mutations in Candida albicans Sterol 14-α Demethylase (CYP51) Reduce In Vitro Inhibition by Fluconazole by WARRILOW, Andrew G. S, MULLINS, Jonathan G. L, HULL, Claire M, PARKER, Josie E, LAMB, David C, KELLY, Diane E, KELLY, Steven L

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Mitigation of human-pathogenic fungi that exhibit resistance to medical agents: can clinical antifungal stewardship help? by Hull, Claire M, Purdy, Nicola J, Moody, Suzy C

“…Reducing indiscriminate antimicrobial usage to combat the expansion of multidrug-resistant human-pathogenic bacteria is fundamental to clinical antibiotic…”
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Co-production of bioethanol and probiotic yeast biomass from agricultural feedstock: application of the rural biorefinery concept by Hull, Claire M, Loveridge, E Joel, Donnison, Iain S, Kelly, Diane E, Kelly, Steven L

“…Microbial biotechnology and biotransformations promise to diversify the scope of the biorefinery approach for the production of high-value products and…”
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Use of 70% alcohol for the routine removal of microbial hard surface bioburden in life science cleanrooms by Salvage, Richard, Hull, Claire M, Kelly, Diane E, Kelly, Steven L

“…Alcohol-based disinfectants are used for the removal of microbial hard surface bioburden in Life science Cleanrooms. Evidence for using formulations containing…”
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Nonantifungal clinical drug interventions and human-commensal fungi: what are we selecting? by Hull, Claire M, Purdy, Nicola J

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Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock by Hull, Claire M, Loveridge, E Joel, Rolley, Nicola J, Donnison, Iain S, Kelly, Steven L, Kelly, Diane E

“…Genetically customised Saccharomyces cerevisiae that can produce ethanol and additional bio-based chemicals from sustainable agro-industrial feedstocks (for…”
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Co-production of 11α-hydroxyprogesterone and ethanol using recombinant yeast expressing fungal steroid hydroxylases by Hull, Claire M, Warrilow, Andrew G S, Rolley, Nicola J, Price, Claire L, Donnison, Iain S, Kelly, Diane E, Kelly, Steven L

“…Bioethanol production from sustainable sources of biomass that limit effect on food production are needed and in a biorefinery approach co-products are…”
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NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia by Hull, Claire, Dekeryte, Ruta, Buchanan, Heather, Kamli-Salino, Sarah, Robertson, Avril, Delibegovic, Mirela, Platt, Bettina

“…The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome has been implicated as a crucial component in both neurodegeneration and diabetes…”
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Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer’s disease by Koss, David J., Dubini, Marina, Buchanan, Heather, Hull, Claire, Platt, Bettina

“…•Two distinct phospho-dependent profiles of insoluble tau deposition are apparent.•Soluble tau and Aβ better correlate with AD progression than insoluble…”
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Neurochemical, histological, and behavioral profiling of the acute, sub‐acute, and chronic MPTP mouse model of Parkinsonʼs disease by Santoro, Matteo, Fadda, Paola, Klephan, Katie J., Hull, Claire, Teismann, Peter, Platt, Bettina, Riedel, Gernot

“…Parkinson's disease (PD) is a heterogeneous multi‐systemic disorder unique to humans characterized by motor and non‐motor symptoms. Preclinical experimental…”
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Molecular Predictors of Cognitive Involvement in Female Carriers of Fragile X Syndrome by Taylor, Annette K, Safanda, John F, Fall, Majilinde Z, Quince, Cindy, Lang, Kirsten A, Hull, Claire E, Carpenter, Isabelle, Staley, Louise W, Hagerman, Randi J

“…Objective.—Fragile X syndrome is caused by a mutation involving expansion of a CGG trinucleotide repeat segment in the fragile X mental retardation—1 (FMR1)…”
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Knock-in of Mutated hTAU Causes Insulin Resistance, Inflammation and Proteostasis Disturbance in a Mouse Model of Frontotemporal Dementia by Hull, Claire, Dekeryte, Ruta, Koss, David J., Crouch, Barry, Buchanan, Heather, Delibegovic, Mirela, Platt, Bettina

“…Diabetes and obesity have been implicated as risk factors for dementia. However, metabolic mechanisms and associated signalling pathways have not been…”
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