Search Results - "Hulka, Lea M"
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Cognitive dysfunctions in recreational and dependent cocaine users: role of attention-deficit hyperactivity disorder, craving and early age at onset
Published in British journal of psychiatry (01-07-2013)“…Dependent cocaine users consistently display cognitive deficits but cognitive performance of recreational cocaine users has rarely been investigated. To…”
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2
Neurometabolic profile of the amygdala in smokers assessed with 1H-magnetic resonance spectroscopy
Published in NeuroImage (Orlando, Fla.) (01-03-2024)“…•Amygdalar neurometabolites were measured reliably with high anatomical specificity.•Glutamate and other neurometabolites did not differ between smokers and…”
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3
Functional changes of the reward system underlie blunted response to social gaze in cocaine users
Published in Proceedings of the National Academy of Sciences - PNAS (18-02-2014)“…Social interaction deficits in drug users likely impede treatment, increase the burden of the affected families, and consequently contribute to the high costs…”
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4
Plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density
Published in Translational psychiatry (19-10-2023)“…Animal models indicate that the endocannabinoid system (ECS) plays a modulatory role in stress and reward processing, both crucially impaired in addictive…”
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5
Longitudinal changes in cocaine intake and cognition are linked to cortical thickness adaptations in cocaine users
Published in NeuroImage clinical (01-01-2019)“…Cocaine use has been consistently associated with decreased gray matter volumes in the prefrontal cortex. However, it is unclear if such neuroanatomical…”
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6
Stable self-serving personality traits in recreational and dependent cocaine users
Published in PloS one (02-03-2017)“…Chronic cocaine use has been associated with impairments in social cognition, self-serving and antisocial behavior, and socially relevant personality disorders…”
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Improvement of Emotional Empathy and Cluster B Personality Disorder Symptoms Associated With Decreased Cocaine Use Severity
Published in Frontiers in psychiatry (05-04-2019)“…Chronic cocaine users display impaired social cognitive abilities, reduced prosocial behavior, and pronounced cluster B personality disorder (PD) symptoms all…”
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Accumbal-thalamic connectivity and associated glutamate alterations in human cocaine craving: A state-dependent rs-fMRI and 1H-MRS study
Published in NeuroImage clinical (01-01-2023)“…•A multimodal imaging study captures craving-related changes in cocaine use disorder.•rs-fMRI assessed functional connectivity (FC) during cue-induced craving…”
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9
Social and Non-Social Cognitive Enhancement in Cocaine Users-A Closer Look on Enhancement Motives for Cocaine Consumption
Published in Frontiers in psychiatry (30-06-2020)“…Cognitive disturbances of chronic cocaine users (CU) have been repeatedly investigated. However, it is yet unknown how CU using cocaine for cognitive or social…”
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10
Risky Decisions in a Lottery Task Are Associated with an Increase of Cocaine Use
Published in Frontiers in psychology (2016)“…Cocaine use disorder is associated with maladaptive decision-making behavior, which strongly contributes to the harmful consequences of chronic drug use. Prior…”
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Cocaine users manifest impaired prosodic and cross-modal emotion processing
Published in Frontiers in psychiatry (2013)“…A small number of previous studies have provided evidence that cocaine users (CU) exhibit impairments in complex social cognition tasks, while the more basic…”
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12
Cognitive Impairment in Cocaine Users is Drug-Induced but Partially Reversible: Evidence from a Longitudinal Study
Published in Neuropsychopharmacology (New York, N.Y.) (01-08-2014)“…Cocaine users consistently display cognitive impairments. However, it is still unknown whether these impairments are cocaine-induced and if they are…”
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13
Impaired glutamate homeostasis in the nucleus accumbens in human cocaine addiction
Published in Molecular psychiatry (01-09-2021)“…Cocaine addiction is characterized by overwhelming craving for the substance, which drives its escalating use despite adverse consequences. Animal models…”
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14
Impaired emotional empathy and related social network deficits in cocaine users
Published in Addiction biology (01-05-2014)“…Chronic cocaine users consistently display neurochemical and functional alterations in brain areas involved in social cognition (e.g. medial and orbitofrontal…”
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Disentangling craving‐ and valence‐related brain responses to smoking cues in individuals with nicotine use disorder
Published in Addiction biology (01-01-2022)“…Tobacco smoking is one of the leading causes of preventable death and disease worldwide. Most smokers want to quit, but relapse rates are high. To improve…”
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Neurometabolic alterations in the nucleus accumbens of smokers assessed with 1H magnetic resonance spectroscopy: The role of glutamate and neuroinflammation
Published in Addiction biology (01-11-2021)“…Tobacco use is one of the leading causes of premature death and morbidity worldwide. For smokers trying to quit, relapse rates are high, even after prolonged…”
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17
Differences in self-reported and behavioral measures of impulsivity in recreational and dependent cocaine users
Published in Drug and alcohol dependence (01-11-2013)“…Abstract Background Dependent cocaine users consistently display increased trait impulsivity on self-report questionnaires and less consistently exhibit…”
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Cognitive and neuroanatomical impairments associated with chronic exposure to levamisole-contaminated cocaine
Published in Translational psychiatry (27-10-2018)“…Currently, levamisole is the most common cocaine adulterant worldwide and it is known to induce a variety of adverse side effects. Animal studies and human…”
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Neurometabolic alterations in the nucleus accumbens of smokers assessed with 1 H magnetic resonance spectroscopy: The role of glutamate and neuroinflammation
Published in Addiction biology (01-11-2021)“…Tobacco use is one of the leading causes of premature death and morbidity worldwide. For smokers trying to quit, relapse rates are high, even after prolonged…”
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Dextromethorphan Abuse Among Opioid-Dependent Patients
Published in Clinical neuropharmacology (01-09-2020)“…Among opioid-dependent patients on maintenance therapy, concomitant drug abuse is a serious problem. Dextromethorphan, an over-the-counter antitussive agent…”
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