Search Results - "Hulegardh, E."

Characterization of therapy-related acute myeloid leukemia: increasing incidence and prognostic implications by Nilsson, Christer, Linde, Fredrika, Hulegårdh, Erik, Garelius, Hege, Lazarevic, Vladimir, Antunovic, Petar, Cammenga, Jörg, Deneberg, Stefan, Eriksson, Anna, Jädersten, Martin, Björkvall, Cecilia Kämpe, Möllgård, Lars, Wennström, Lovisa, Ölander, Emma, Höglund, Martin, Juliusson, Gunnar, Lehmann, Sören

“…Studies of therapy-related AML (t-AML) are usually performed in selected cohorts and reliable incidence rates are lacking. In this study, we characterized,…”
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Risk group assignment differs for children and adults 1-45 yr with acute lymphoblastic leukemia treated by the NOPHO ALL-2008 protocol by Toft, Nina, Birgens, Henrik, Abrahamsson, Jonas, Bernell, Per, Griškevičius, Laimonas, Hallböök, Helene, Heyman, Mats, Holm, Mette Skov, Hulegårdh, Erik, Klausen, Tobias Wirenfeldt, Marquart, Hanne V., Jónsson, Ólafur Gísli, Nielsen, Ove Juul, Quist-Paulsen, Petter, Taskinen, Mervi, Vaitkeviciene, Goda, Vettenranta, Kim, Åsberg, Ann, Schmiegelow, Kjeld

“…Background The prognosis of acute lymphoblastic leukemia is poorer in adults than in children. Studies have indicated that young adults benefit from pediatric…”
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RELAPSE OF ACUTE LYMPHOBLASTIC LEUKAEMIA IN OLDER/ELDERLY PATIENTS: A SWEDISH POPULATION-BASED STUDY by Bergfelt, E., Kozlowski, Piotr, Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Åström, Maria, Hallböök, H.

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Recurrent venous thromboembolism in anticoagulated patients with cancer: management and short‐term prognosis by Schulman, S., Zondag, M., Linkins, L., Pasca, S., Cheung, Y. W., Sancho, M., Gallus, A., Lecumberri, R., Molnar, S., Ageno, W., Le Gal, G., Falanga, A., Hulegårdh, E., Ranta, S., Kamphuisen, P., Debourdeau, P., Rigamonti, V., Ortel, T. L., Lee, A.

“…Summary Background Recommendations for management of cancer‐related venous thromboembolism (VTE) in patients already receiving anticoagulant therapy are based…”
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MINIMAL RESIDUAL DISEASE IN ADULTS WITH PHILADELPHIA NEGATIVE B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA A SWEDISH POPULATION-BASED STUDY by Bergfelt, E., Kozlowski, P., Ahlberg, L., Hulegardh, E., Hagglund, H., Karlsson, K., Markuszewska-Kuczymska, Alicja, Tomaszewska-Toporska, B., Smedmyr, B., Astrom, M., Amini, R. M., Hallbook, H.

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Incidence and prognostic significance of karyotypic subgroups in older patients with acute myeloid leukemia: the Swedish population-based experience by Lazarevic, V, Hörstedt, A-S, Johansson, B, Antunovic, P, Billström, R, Derolf, Å, Hulegårdh, E, Lehmann, S, Möllgård, L, Nilsson, C, Peterson, S, Stockelberg, D, Uggla, B, Wennström, L, Wahlin, A, Höglund, M, Juliusson, G

“…The Swedish population-based acute myeloid leukemia registry contains data from 3251 patients (excluding acute promyelocytic leukemia) diagnosed between 1997…”
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Prognosis in older/elderly patients with acute lymphoblastic leukaemia diagnosed 2005-2012: results from a Swedish population-based study by Bergfelt, E., Kozlowski, Piotr, Åström, Maria, Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Hallböök, H.

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Characterization and prognostic features of secondary acute myeloid leukemia in a population‐based setting: A report from the Swedish Acute Leukemia Registry by Hulegårdh, Erik, Nilsson, Christer, Lazarevic, Vladimir, Garelius, Hege, Antunovic, Petar, Rangert Derolf, Åsa, Möllgård, Lars, Uggla, Bertil, Wennström, Lovisa, Wahlin, Anders, Höglund, Martin, Juliusson, Gunnar, Stockelberg, Dick, Lehmann, Sören

“…Patients with secondary acute myeloid leukemia (AML) often escape inclusion in clinical trials and thus, population‐based studies are crucial for its accurate…”
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Outcome after HSCT in Philadelphia chromosome positive acute lymphoblastic leukemia in Sweden: a population-based study by Hulegårdh, E., Hägglund, H., Ahlberg, L., Karlsson, K., Karbach, H., Markuszewska, A., Persson, I., Åström, M., Hallböök, H.

“…Even in the tyrosine kinase inhibitor era, allogeneic hematopoietic stem cell transplantation (HSCT) is regarded as standard care for adult Philadelphia (Ph)…”
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Survival in adult acute lymphoblastic leukaemia (ALL): A report from the Swedish ALL Registry by Lennmyr, Emma, Karlsson, Karin, Ahlberg, Lucia, Garelius, Hege, Hulegårdh, Erik, Izarra, Antonio S, Joelsson, Joel, Kozlowski, Piotr, Moicean, Andreea, Tomaszewska‐Toporska, Beata, Lübking, Anna, Hallböök, Helene

“…Objectives As new, effective therapies emerge for acute lymphoblastic leukaemia (ALL), the results of clinical trials need to relate to standard of care…”
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Age but not Philadelphia positivity impairs outcome in older/elderly patients with acute lymphoblastic leukemia in Sweden by Kozlowski, Piotr, Lennmyr, Emma, Ahlberg, Lucia, Bernell, Per, Hulegårdh, Erik, Karbach, Holger, Karlsson, Karin, Tomaszewska‐Toporska, Beata, Åström, Maria, Hallböök, Heléne

“…Objectives Older/elderly patients with acute lymphoblastic leukemia (ALL) are poorly represented in clinical trials. Methods Using Swedish national leukemia…”
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NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia by Tulstrup, Morten, Grosjean, Marie, Nielsen, Stine Nygaard, Grell, Kathrine, Wolthers, Benjamin Ole, Wegener, Peder Skov, Jonsson, Olafur Gisli, Lund, Bendik, Harila-Saari, Arja, Abrahamsson, Jonas, Vaitkeviciene, Goda, Pruunsild, Kaie, Toft, Nina, Holm, Mette, Hulegårdh, Erik, Liestøl, Sigurd, Griskevicius, Laimonas, Punab, Mari, Wang, Jinhua, Carroll, William L., Zhang, Zeyu, Dalgaard, Marlene D., Gupta, Ramneek, Nersting, Jacob, Schmiegelow, Kjeld

“…The antileukaemic drug 6-mercaptopurine is converted into thioguanine nucleotides (TGN) and incorporated into DNA (DNA-TG), the active end metabolite. In a…”
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Real-world data on first relapse of acute lymphoblastic leukemia in patients >55 years by Lennmyr, Emma Bergfelt, Kozlowski, Piotr, Ahlberg, Lucia, Bernell, Per, Hulegårdh, Erik, Izarra, Antonio Santamaria, Karlsson, Karin, Tomaszewska-Toporska, Beata, Åström, Maria, Hallböök, Helene

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High relapse rate of T cell acute lymphoblastic leukemia in adults treated with Hyper-CVAD chemotherapy in Sweden by Kozlowski, Piotr, Åström, Maria, Ahlberg, Lucia, Bernell, Per, Hulegårdh, Erik, Hägglund, Hans, Karlsson, Karin, Markuszewska-Kuczymska, Alicja, Tomaszewska-Toporska, Beata, Smedmyr, Bengt, Amini, Rose-Marie, Hallböök, Helene

“…Background Hyper‐CVAD is widely used to treat acute lymphoblastic leukemia (ALL) and aggressive lymphomas. This multicenter, population‐based study assessed…”
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High curability via intensive reinduction chemotherapy and stem cell transplantation in young adults with relapsed acute lymphoblastic leukemia in Sweden 2003–2007 by KOZLOWSKI, Piotr, ASTRÖM, Maria, HALLBÖÖK, Helene, AHLBERG, Lucia, BERNELL, Per, HULEGARDH, Erik, HÄGGLUND, Hans, KARLSSON, Karin, MARKUSZEWSKA-KUCZYMSKA, Alicja, TOMASZEWSKA-TOPORSKA, Beata, SMEDMYR, Bengt

“…A minority of patients with adult acute lymphoblastic leukemia who relapse are rescued. The aim of this population-based study was to assess the results of…”
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Allogeneic Transplantation in First Remission Improves Outcome in Secondary Acute Myeloid Leukemia by Nilsson, Christer, Hulegårdh, Erik, Lazarevic, Vladimir, Garelius, Hege, Derolf, Asa Rangert, Möllgård, Lars, Wennström, Lovisa, Uggla, Bertil, Antunovic, Petar, Myhr-Eriksson, Kristina, Wahlin, Anders, Höglund, Martin, Juliusson, Gunnar, Stockelberg, Dick, Soren, Lehmann

“…Allogeneic stem cell transplantation (SCT) is widely used as post-remission treatment in younger patients with poor or intermediate risk AML. Transplant…”
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Secondary Acute Myeloid Leukemia and the Role of Allogeneic Stem Cell Transplantation in a Population-Based Setting by Nilsson, Christer, Hulegårdh, Erik, Garelius, Hege, Möllgård, Lars, Brune, Mats, Wahlin, Anders, Lenhoff, Stig, Frödin, Ulla, Remberger, Mats, Höglund, Martin, Juliusson, Gunnar, Stockelberg, Dick, Lehmann, Sören

“…•In a population-based setting, the proportion of patients with acute myeloid leukemia (AML) achieving complete remission who undergo allogeneic hematopoietic…”
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Satisfactory outcome after intensive chemotherapy with pragmatic use of minimal residual disease (MRD) monitoring in older patients with Philadelphia-negative B cell precursor acute lymphoblastic leukaemia: a Swedish registry-based study by Bergfelt, Emma, Kozlowski, Piotr, Ahlberg, Lucia, Hulegårdh, Erik, Hägglund, Hans, Karlsson, Karin, Markuszewska-Kuczymska, Alicja, Tomaszewska-Toporska, Beata, Smedmyr, Bengt, Åström, Maria, Amini, Rose-Marie, Hallböök, Heléne

“…The introduction of minimal residual disease (MRD) monitoring, in the Swedish national guidelines for acute lymphoblastic leukaemia, was evaluated in 35…”
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PROGNOSTIC ROLE OF CHROMOSOMAL ABNORMALITIES AND MONOSOMAL KARYOTYPE IN AML FROM A POPULATION-BASED PERSPECTIVE: EXPERIENCE FROM THE SWEDISH ACUTE MYELOID LEUKEMIA REGISTRY by Lazarevic, V, Horstedt, AS, Antunovic, P, Brune, M, Derolf, A, Hulegardh, E, Lehmann, S, Mollgard, L, Nilsson, C, Stockelberg, D, Uggla, B, Vennstrom, L, Wahlin, A, Hoglund, M, Juliusson, G

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Improved results of allogeneic stem cell transplantation for adult Ph plus ALL patients in the TKI era - the Swedish experience by Hagglund, H, Karlsson, K, Hulegardh, E, Karbach, H, Markuszewska, A, Astrom, M, Hallbook, H

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