Search Results - "Huizar, Isham"

MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis by Gharib, Sina A., Johnston, Laura K., Huizar, Isham, Birkland, Timothy P., Hanson, Josiah, Wang, Ying, Parks, William C., Manicone, Anne M.

“…MMP28 promotes alternatively activated (M2) macrophage function, and regulates the fibrotic response in the lung. Members of the MMP family function in various…”
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Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis by Malur, Anagha, Kavuru, Mani S, Marshall, Irene, Barna, Barbara P, Huizar, Isham, Karnekar, Reema, Thomassen, Mary Jane

“…Pulmonary Alveolar Proteinosis (PAP) patients exhibit an acquired deficiency of biologically active granulocyte-macrophage colony stimulating factor (GM-CSF)…”
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The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation by Huizar, Isham, Malur, Anagha, Patel, Janki, McPeek, Matthew, Dobbs, Larry, Wingard, Christopher, Barna, Barbara P, Thomassen, Mary Jane

“…Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are poorly…”
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Insulin-like Growth Factor-I Receptor Blockade Improves Outcome in Mouse Model of Lung Injury by Choi, Jung-Eun, Lee, Sung-soon, Sunde, Donald A, Huizar, Isham, Haugk, Kathy L, Thannickal, Victor J, Vittal, Ragini, Plymate, Stephen R, Schnapp, Lynn M

“…The insulin-like growth factor-I (IGF-I) pathway is an important determinant of survival and proliferation in many cells. However, little is known about the…”
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Use of a Dual Lumen Endobronchial Tube With a Bronchial Blocker to Treat Massive Hemoptysis by Orellana-Barrios, Menfil, MD, Yepes-Hurtado, Andres, MD, Huizar, Isham, MD

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Carbon nanotube-induced pulmonary granulomatous disease: Twist1 and alveolar macrophage M1 activation by Barna, Barbara P, Huizar, Isham, Malur, Anagha, McPeek, Matthew, Marshall, Irene, Jacob, Mark, Dobbs, Larry, Kavuru, Mani S, Thomassen, Mary Jane

“…Sarcoidosis, a chronic granulomatous disease of unknown cause, has been linked to several environmental risk factors, among which are some that may favor…”
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Alveolar macrophage activation in obese patients with obstructive sleep apnea by Sharma, Sunil, MD, Malur, Anagha, MS, Marshall, Irene, PA-C, Huizar, Isham, MD, Barna, Barbara P., PhD, Pories, Walter, MD, Dohm, Lynis, PhD, Kavuru, Mani S., MD, Thomassen, Mary Jane, PhD

“…Background Classically, activated macrophages in adipose tissue, liver, and muscle have been implicated in many conditions associated with obesity, including…”
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Metastatic Pulmonary Calcification An Uncommon Clinical Condition in End-Stage Renal Disease by Patel, Gaurav, Yepes-Hurtado, Andre, Huizar, Isham

“…Patients with end-stage renal diseases have frequent pulmonary complicationsrelated to fluid overload, infection, and associated cardiovascular diseases. We…”
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Safety and efficacy of ustekinumab or golimumab in patients with chronic sarcoidosis by JUDSON, Marc A, BAUGHMARI, Robert P, WIJSENBEEK, Marlies S, ALBERA, Carlo, HUIZAR, Isham, AGARWAL, Prasheen, BRODMERKEL, Carrie, WATT, Rosemary, BARNATHAN, Elliot S, COSTABEL, Ulrich, DRENT, Marjolein, GIBSON, Kevin F, RAGHU, Ganesh, SHIGEMITSU, Hidenobu, BARNEY, Joseph B, CULVER, Daniel A, HAMZEH, Nabeel Y

“…Sarcoidosis is characterised by non-caseating granulomas that secrete pro-inflammatory cytokines, including interleukin (IL)-12, IL-23, and tumour necrosis…”
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Delphi consensus recommendations for a treatment algorithm in pulmonary sarcoidosis by Rahaghi, Franck F, Baughman, Robert P, Saketkoo, Lesley Ann, Sweiss, Nadera J, Barney, Joseph B, Birring, Surinder S, Costabel, Ulrich, Crouser, Elliott D, Drent, Marjolein, Gerke, Alicia K, Grutters, Jan C, Hamzeh, Nabeel Y, Huizar, Isham, Ennis James, 4th, W, Kalra, Sanjay, Kullberg, Susanna, Li, Huiping, Lower, Elyse E, Maier, Lisa A, Mirsaeidi, Mehdi, Müller-Quernheim, Joachim, Carmona Porquera, Eva M, Samavati, Lobelia, Valeyre, Dominique, Scholand, Mary Beth

“…Pulmonary sarcoidosis presents substantial management challenges, with limited evidence on effective therapies and phenotypes. In the absence of definitive…”
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Matrilysin (Matrix Metalloproteinase-7) Regulates Anti-Inflammatory and Antifibrotic Pulmonary Dendritic Cells That Express CD103 (αE β7 -Integrin) by Manicone, Anne M, Huizar, Isham, McGuire, John K

“…The E-cadherin receptor CD103 (αE β7 -integrin) is expressed on specific populations of pulmonary dendritic cells (DC) and T cells. However, CD103 function in…”
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Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin) by Manicone, Anne M, Huizar, Isham, McGuire, John K

“…The E-cadherin receptor CD103 (alpha(E)beta(7)-integrin) is expressed on specific populations of pulmonary dendritic cells (DC) and T cells. However, CD103…”
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Alveolar proteinosis syndrome: pathogenesis, diagnosis, and management by Huizar, Isham, Kavuru, Mani S

“…PURPOSE OF REVIEWThis review discusses the most recent clinical and basic research literature on pulmonary alveolar proteinosis (PAP) as it relates to…”
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An open-label trial of rituximab therapy in pulmonary alveolar proteinosis by KAVURU, M. S, MALUR, A, MARSHALL, I, BARNA, B. P, MEZIANE, M, HUIZAR, I, DALRYMPLE, H, KARNEKAR, R, THOMASSEN, M. J

“…Rituximab, a monoclonal antibody directed against the B-lymphocyte antigen CD20, has shown promise in several autoimmune disorders. Pulmonary alveolar…”
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Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells by Gharib, Sina A, Malur, Anagha, Huizar, Isham, Barna, Barbara P, Kavuru, Mani S, Schnapp, Lynn M, Thomassen, Mary Jane

“…Sarcoidosis is a multisystem immuno-inflammatory disorder of unknown etiology that most commonly involves the lungs. We hypothesized that an unbiased approach…”
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Tissue Inhibitor of Metalloproteinases 3 Regulates Resolution of Inflammation following Acute Lung Injury by Gill, Sean E, Huizar, Isham, Bench, Eli M, Sussman, Samuel W, Wang, Ying, Khokha, Rama, Parks, William C

“…Tissue inhibitor of metalloproteinases 3 (TIMP3) inhibits not only matrix metalloproteinases but also a disintegrin and metalloproteinase domain family members…”
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Novel murine model of chronic granulomatous lung inflammation elicited by carbon nanotubes by Huizar, Isham, Malur, Anagha, Midgette, Yasmeen A, Kukoly, Cindy, Chen, Pengyu, Ke, Pu Chun, Podila, Ramakrishna, Rao, Apparao M, Wingard, Christopher J, Dobbs, Larry, Barna, Barbara P, Kavuru, Mani S, Thomassen, Mary Jane

“…Lung granulomas are associated with numerous conditions, including inflammatory disorders, exposure to environmental pollutants, and infection. Osteopontin is…”
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The effect of disease modifying drugs on the lung in patients with rheumatoid arthritis by Tashfeen Mahmood, Jose Cuevas, Isham Huizar, Kenneth Nugent

“…Rheumatoid arthritis (RA) is a systemic inflammatory disease mainly affecting the joints. It has extra-articular manifestations, including lung disease, a…”
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Lentivirus-ABCG1 instillation reduces lipid accumulation and improves lung compliance in GM-CSF knock-out mice by Malur, Anagha, Huizar, Isham, Wells, Greg, Barna, Barbara P., Malur, Achut G., Thomassen, Mary Jane

“…► Lentivirus-ABCG1 reduces lipid accumulation in lungs of GM-CSF knock-out mice. ► Up-regulation of ABCG1 improves lung function. ► Upregulation of ABCG1…”
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The role of PPAR[gamma] in carbon nanotube-elicited granulomatous lung inflammation by Huizar, Isham, Malur, Anagha, Patel, Janki, McPeek, Matthew, Dobbs, Larry, Wingard, Christopher, Barna, Barbara P, Thomassen, Mary Jane

“…Background Although granulomatous inflammation is a central feature of many disease processes, cellular mechanisms of granuloma formation and persistence are…”
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