Search Results - "Huitfeldt, Henrik S"

Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX by De Angelis, Paula M, Schjølberg, Aasa R, Hughes, Juliana B, Huitfeldt, Henrik S, Norheim Andersen, Solveig, Østvold, Anne Carine

“…Abstract Background The colon and rectum are continuously exposed to oxidative stress that generates reactive oxygen species, which are a major cause of DNA…”
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Growth of hepatocellular carcinoma in the regenerating liver by Shi, Ji‐Hua, Huitfeldt, Henrik S., Suo, Zhen‐He, Line, Pål‐Dag

“…Liver resection and liver transplantation are the treatment modalities with the greatest potential for curing hepatocellular carcinoma (HCC). Tumor recurrence…”
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EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase by Flinder, Liv Ingrid, Timofeeva, Olga A., Rosseland, Carola M., Wierød, Lene, Huitfeldt, Henrik S., Skarpen, Ellen

“…Reactive oxygen species (ROS) function as signaling molecules mainly by reversible oxidation of redox‐sensitive target proteins. ROS can be produced in…”
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EGF Activates Autocrine TGFα to Induce Prolonged EGF Receptor Signaling and Hepatocyte Proliferation by Liu, ShuZheng, Wierød, Lene, Skarpen, Ellen, Grøsvik, Helga, Duan, GuangCai, Huitfeldt, Henrik S.

“…Background/Aims: EGF receptor is a main participant in the regulation of liver regeneration. In primary hepatocyte cultures, EGF or TGFα binding to EGF…”
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Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes by ROSSELAND, Carola M, WIERØD, Lene, OKSVOLD, Morten P, WERNER, Heidi, ØSTVOLD, Anne Carine, THORESEN, G. Hege, PAULSEN, Ragnhild E, HUITFELDT, Henrik S, SKARPEN, Ellen

“…Reactive oxygen species (ROS) are implicated in tissue damage causing primary hepatic dysfunction following ischemia/reperfusion injury and during inflammatory…”
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Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors by Paasche, Joachim D, Attramadal, Toril, Kristiansen, Kurt, Oksvold, Morten P, Johansen, Heidi K, Huitfeldt, Henrik S, Dahl, Svein G, Attramadal, Håvard

“…We have previously reported that endocytic sorting of ET(A) endothelin receptors to the recycling pathway is dependent on a signal residing in the cytoplasmic…”
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Deletion of the γ-Aminobutyric Acid Transporter 2 (GAT2 and SLC6A13) Gene in Mice Leads to Changes in Liver and Brain Taurine Contents by Zhou, Yun, Holmseth, Silvia, Guo, Caiying, Hassel, Bjørnar, Höfner, Georg, Huitfeldt, Henrik S., Wanner, Klaus T., Danbolt, Niels C.

“…The GABA transporters (GAT1, GAT2, GAT3, and BGT1) have mostly been discussed in relation to their potential roles in controlling the action of transmitter…”
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Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene by Brinchmann, Bendik C., Le Ferrec, Eric, Bisson, William H., Podechard, Normand, Huitfeldt, Henrik S., Gallais, Isabelle, Sergent, Odile, Holme, Jørn A., Lagadic-Gossmann, Dominique, Øvrevik, Johan

“…[Display omitted] In its classical genomic mode of action, the aryl hydrocarbon receptor (AhR) acts as a ligand activated transcription factor regulating…”
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Regulation of rat alveolar type 2 cell proliferation in vitro involves type II cAMP-dependent protein kinase by Samuelsen, Jan T, Schwarze, Per E, Huitfeldt, Henrik S, Thrane, E Vibeke, Låg, Marit, Refsnes, Magne, Skarpen, Ellen, Becher, Rune

“…To elucidate the role of cAMP and different cAMP-dependent protein kinases (PKA; A-kinase) in lung cell proliferation, we investigated rat alveolar type 2 cell…”
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Structure function analysis of SH2D2A isoforms expressed in T cells reveals a crucial role for the proline rich region encoded by SH2D2A exon 7 by Granum, Stine, Sundvold-Gjerstad, Vibeke, Dai, Ke-Zheng, Kolltveit, Kristin Melkevik, Hildebrand, Kjersti, Huitfeldt, Henrik S, Lea, Tor, Spurkland, Anne

“…The activation induced T cell specific adapter protein (TSAd), encoded by SH2D2A, interacts with and modulates Lck activity. Several transcript variants of…”
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The effect of hepatic progenitor cells on experimental hepatocellular carcinoma in the regenerating liver by Shi, Ji-Hua, Scholz, Hanne, Huitfeldt, Henrik S., Line, Pål-Dag

“…Abstract Objective. Liver regeneration following hepatectomy can stimulate the growth of hepatocellular carcinoma (HCC), and major hepatectomy can be…”
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FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes by Flinder, Liv Ingrid, Wierød, Lene, Rosseland, Carola M., Huitfeldt, Henrik S., Skarpen, Ellen

“…In this study, we report a novel role of FAK as a regulator of Cdk2 in anchorage‐dependent primary cultured hepatocytes. In response to EGF, we found that…”
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Environmental toxins in Norwegian food by Huitfeldt, Henrik S, Bolann, Bjørn J

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RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver by Shi, Ji-Hua, Liu, Shu-Zheng, Wierød, Lene, Scholz, Hanne, Anmarkrud, Jarl Andreas, Huitfeldt, Henrik S., Zhang, Shui-Jun, Line, Pål-Dag

“…Background Post‐operative liver regeneration may contribute to tumor recurrence. There is a theoretical need for an adjuvant therapy that can suppress tumor…”
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Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS by Grundt, Kirsten, Haga, Ingvild V., Huitfeldt, Henrik S., Østvold, Anne Carine

“…Immunofluorescence analyses show that the vertebrate specific and DNA-binding protein NUCKS is distributed throughout the cytoplasm in mitotic cells and…”
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Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K by Rosseland, Carola M., Wierød, Lene, Flinder, Liv I., Oksvold, Morten P., Skarpen, Ellen, Huitfeldt, Henrik S.

“…Ras proteins mediate signals both via extracellular signal‐regulated kinase 1 and 2 (ERK), and phosphoinositide 3‐kinase (PI3K). These signals are key events…”
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Identification of 14-3-3ζ as an EGF receptor interacting protein by Oksvold, Morten P, Huitfeldt, Henrik S, Langdon, Wallace Y

“…The 14-3-3 proteins are known to interact with a number of proteins involved in the regulation of cell signaling. Here, we describe an association of 14-3-3ζ…”
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Er miljøgifter i norsk kosthold skadelig for barn? by Bolann, Bjørn J, Huber, Sandra, Ruzzin, Jerome, Brox, Jan, Huitfeldt, Henrik S, Monsen, Anne-Lise Bjørke

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Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor by OKSVOLD, Morten P, THIEN, Christine B. F, WIDERBERG, Jannicke, CHANTRY, Andrew, HUITFELDT, Henrik S, LANGDON, Wallace Y

“…In the present study, we examined EGF-induced internalization, degradation and trafficking of the epidermal growth factor receptor (EGFR) mutated at serines…”
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Miljøgifter i kosten handler om mer enn fisk by Bolann, Bjørn J, Huber, Sandra, Ruzzin, Jerome, Brox, Jan, Huitfeldt, Henrik S, Monsen, Anne-Lise Bjørke

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