Search Results - "Huisman, Berend J. H."

Generative Recurrent Networks for De Novo Drug Design by Gupta, Anvita, Müller, Alex T., Huisman, Berend J. H., Fuchs, Jens A., Schneider, Petra, Schneider, Gisbert

“…Generative artificial intelligence models present a fresh approach to chemogenomics and de novo drug design, as they provide researchers with the ability to…”
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Combining generative artificial intelligence and on-chip synthesis for de novo drug design by Grisoni, Francesca, Huisman, Berend J H, Button, Alexander L, Moret, Michael, Atz, Kenneth, Merk, Daniel, Schneider, Gisbert

“…Automating the molecular design-make-test-analyze cycle accelerates hit and lead finding for drug discovery. Using deep learning for molecular design and a…”
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5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A2A Receptor by Massink, Arnault, Louvel, Julien, Adlere, Ilze, van Veen, Corine, Huisman, Berend J. H, Dijksteel, Gabrielle S, Guo, Dong, Lenselink, Eelke B, Buckley, Benjamin J, Matthews, Hayden, Ranson, Marie, Kelso, Michael, IJzerman, Adriaan P

“…The sodium ion site is an allosteric site conserved among many G protein-coupled receptors (GPCRs). Amiloride 1 and 5-(N,N-hexamethylene)­amiloride 2 (HMA)…”
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Erratum: Generative Recurrent Networks for De Novo Drug Design by Gupta, Anvita, Müller, Alex T., Huisman, Berend J. H., Fuchs, Jens A., Schneider, Petra, Schneider, Gisbert

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5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A 2A Receptor by Massink, Arnault, Louvel, Julien, Adlere, Ilze, van Veen, Corine, Huisman, Berend J. H., Dijksteel, Gabrielle S., Guo, Dong, Lenselink, Eelke B., Buckley, Benjamin J., Matthews, Hayden, Ranson, Marie, Kelso, Michael, IJzerman, Adriaan P.

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