Search Results - "Huis In't Veld, Ruben V"

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    In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity by Ma, Sen, Huis In't Veld, Ruben V, Houy, Alexander, Stern, Marc-Henri, Rich, Cadmus, Ossendorp, Ferry A, Jager, Martine J

    “…The virus-like drug conjugate belzupacap sarotalocan (AU-011), currently under clinical investigation for first-line treatment of primary uveal melanoma (UM),…”
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    Journal Article
  3. 3

    Treatment of Conjunctival Melanoma Cell Lines With a Light-Activated Virus-Like Drug Conjugate Induces Immunogenic Cell Death by Ma, Sen, Huis In't Veld, Ruben V., de los Pinos, Elisabet, Ossendorp, Ferry A., Jager, Martine J.

    “…Conjunctival melanoma (CJM) is a rare malignant ocular surface tumor, which often leads to local recurrences and metastases. In murine models of subcutaneous…”
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    The role of pigmentation in tumor treatment with the investigational virus-like drug conjugate belzupacap sarotalocan in an in vitro and in vivo murine model by Ma, Sen, In't Veld, Ruben V Huis, Rich, Cadmus, Ossendorp, Ferry A., Jager, Martine J.

    Published in Photodiagnosis and photodynamic therapy (01-04-2024)
    “…Tumor pigmentation is known to be a barrier for applying photodynamic therapy in ocular melanoma. We investigated the role of pigmentation in tumor behavior…”
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    Photodynamic cancer therapy enhances accumulation of nanoparticles in tumor-associated myeloid cells by Huis in 't Veld, Ruben V., Ritsma, Laila, Kleinovink, Jan Willem, Que, Ivo, Ossendorp, Ferry, Cruz, Luis J.

    Published in Journal of controlled release (10-04-2020)
    “…In cancer treatment, nanomedicines may be employed in an attempt to improve the tumor localization of antineoplastic drugs e.g. immunotherapeutic agents either…”
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    Current Challenges and Opportunities of Photodynamic Therapy against Cancer by Huis In 't Veld, Ruben V, Heuts, Jeroen, Ma, Sen, Cruz, Luis J, Ossendorp, Ferry A, Jager, Martine J

    Published in Pharmaceutics (18-01-2023)
    “…Photodynamic therapy (PDT) is an established, minimally invasive treatment for specific types of cancer. During PDT, reactive oxygen species (ROS) are…”
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  7. 7

    Immune checkpoint inhibition combined with targeted therapy using a novel virus-like drug conjugate induces complete responses in a murine model of local and distant tumors by Huis in ‘t Veld, Ruben V., Ma, Sen, Kines, Rhonda C., Savinainen, Anneli, Rich, Cadmus, Ossendorp, Ferry, Jager, Martine J.

    Published in Cancer Immunology, Immunotherapy (01-07-2023)
    “…Metastases remain the leading cause of cancer-related death worldwide. Therefore, improving the treatment efficacy against such tumors is essential to enhance…”
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  8. 8

    M1-derived extracellular vesicles enhance photodynamic therapy and promote immunological memory in preclinical models of colon cancer by Huis In 't Veld, Ruben V, Lara, Pablo, Jager, Martine J, Koning, Roman I, Ossendorp, Ferry, Cruz, Luis J

    Published in Journal of nanobiotechnology (03-06-2022)
    “…Extracellular vesicles (EVs) are promising drug carriers of photosensitizers for photodynamic therapy (PDT) in cancer treatment, due to their ability to…”
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    Journal Article